Publications by authors named "Jared Auclair"

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Charge variant analysis of intact monoclonal antibody reference standards using microfluidic capillary zone electrophoresis.
Noah Gould, Kendall Johnson, Anne-Lise Marie, Jared R Auclair, Alexander R Ivanov

J Pharm Biomed Anal· December 2025

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Immunogenicity risk mitigation of therapeutic proteins with translational immunogenicity, analytical characterization, and regulatory insight.
Sadiqua Shadbar, Sathy V Balu-Iyer, Jared Auclair, Daniel Dadon

J Pharm Sci· November 2025

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Reimagining drug regulation in the age of AI: a framework for the AI-enabled Ecosystem for Therapeutics.
Rominder Singh, Karen Zhou, Jared R Auclair

Front Med (Lausanne)· November 2025

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Regulating the AI-enabled ecosystem for human therapeutics.
Rominder Singh, Mark Paxton, Jared Auclair

Commun Med (Lond)· May 2025

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Mass spectrometry methods and mathematical PK/PD model for decision tree-guided covalent drug development.
Md Amin Hossain, Rutali R Brahme, Brandon C Miller, Jakal Amin, Marcela de Barros, Jared R Auclair

Nat Commun· February 2025

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Site-Specific Conjugation of Native Antibody: Transglutaminase-Mediated Modification of a Conserved Glutamine While Maintaining the Primary Sequence and Core Fc Glycan via Trimming with an Endoglycosidase.
Amissi Sadiki, Shanshan Liu, Shefali R Vaidya, Eric M Kercher, Ryan T Lang, Jared R Auclair

Bioconjug Chem· April 2024

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Comparison of analytical performance and economic value of two biosurveillance methods for tracking SARS-COV-2 variants of concern.
Nicholas P Pinkhover, Kerriann M Pontbriand, Kelli P Fletcher, Eduardo Sanchez, Kenneth Okello, Jared R Auclair

Microbiol Spectr· February 2024

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Evaluation of a Pilot: Inspection Facilitation and Collaboration Using a Mixed Reality Device.
Peter Baker, Tamika Cathey, Jared R Auclair

Ther Innov Regul Sci· January 2024

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Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Md Amin Hossain, Richa Sarin, Daniel P Donnelly, Brandon C Miller, Alexandra Weiss, Jared R Auclair

PLoS Biol· January 2024

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Cross-sectional Ct distributions from qPCR tests can provide an early warning signal for the spread of COVID-19 in communities.
Mahfuza Sharmin, Mani Manivannan, David Woo, Océane Sorel, Jared R Auclair

Front Public Health· October 2023

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Early Introduction and Rise of the Omicron Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant in Highly Vaccinated University Populations.
Brittany A Petros, Jacquelyn Turcinovic, Nicole L Welch, Laura F White, Eric D Kolaczyk, Jared R Auclair

Clin Infect Dis· February 2023

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A Novel Rolling Circle Amplification-Based Detection of SARS-CoV-2 with Multi-Region Padlock Hybridization.
Rajesh Kumari, Ji Won Lim, Matthew Ryan Sullivan, Rachel Malampy, Connor Baush, Jared R Auclair

Diagnostics (Basel)· September 2022

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Performance of the TaqMan COVID-19 Pooling Kit for detection of SARS-CoV-2 in asymptomatic and symptomatic populations.
Troy Ganz, Sarah Sanderson, Connor Baush, Melanie Mejia, Manoj Gandhi, Jared Auclair

PLoS One· June 2022

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Two-Stage Hierarchical Group Testing Strategy to Increase SARS-CoV-2 Testing Capacity at an Institution of Higher Education: A Retrospective Analysis.
Troy J Ganz, Rachel Donner, Kevin M Hines, Markus L Waithe-Alleyne, Deirdre L Slate, Jared R Auclair

J Mol Diagn· December 2021

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Adherence Factor Expression in -Like Conditions.
Rachael B Chanin, Kourtney P Nickerson, Alejandro Llanos-Chea, Jeticia R Sistrunk, David A Rasko, Jared R Auclair

mSphere· November 2019

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Best practices and benchmarks for intact protein analysis for top-down mass spectrometry.
Daniel P Donnelly, Catherine M Rawlins, Caroline J DeHart, Luca Fornelli, Luis F Schachner, Jared R Auclair

Nat Methods· July 2019

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Genetically Encoded Fluorescent Proteins Enable High-Throughput Assignment of Cell Cohorts Directly from MALDI-MS Images.
Nicholas D Schmitt, Catherine M Rawlins, Elizabeth C Randall, Xianzhe Wang, Antonius Koller, Jared R Auclair

Anal Chem· March 2019

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Regulatory Convergence for Biologics through Capacity Building and Training.
Jared R Auclair

Trends Biotechnol· January 2019

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Cyclic Thiosulfinates and Cyclic Disulfides Selectively Cross-Link Thiols While Avoiding Modification of Lone Thiols.
Daniel P Donnelly, Matthew G Dowgiallo, Joseph P Salisbury, Krishna C Aluri, Suhasini Iyengar, Jared R Auclair

J Am Chem Soc· June 2018

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Integrated Bottom-Up and Top-Down Liquid Chromatography-Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products.
Yu Annie Wang, Di Wu, Jared R Auclair, Joseph P Salisbury, Richa Sarin

Anal Chem· December 2017

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Heavy Sugar and Heavy Water Create Tunable Intact Protein Mass Increases for Quantitative Mass Spectrometry in Any Feed and Organism.
Jeniffer V Quijada, Nicholas D Schmitt, Joseph P Salisbury, Jared R Auclair, Jeffrey N Agar

Anal Chem· November 2016

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Mildly acidic conditions eliminate deamidation artifact during proteolysis: digestion with endoprotease Glu-C at pH 4.5.
Shanshan Liu, Kevin Ryan Moulton, Jared Robert Auclair, Zhaohui Sunny Zhou

Amino Acids· April 2016

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The central nervous system transcriptome of the weakly electric brown ghost knifefish (Apteronotus leptorhynchus): de novo assembly, annotation, and proteomics validation.
Joseph P Salisbury, Ruxandra F Sîrbulescu, Benjamin M Moran, Jared R Auclair, Günther K H Zupanc

BMC Genomics· March 2015

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Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis.
Melissa S Rotunno, Jared R Auclair, Stephanie Maniatis, Scott A Shaffer, Jeffrey Agar

J Biol Chem· October 2014

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Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.
Jared R Auclair, Joseph P Salisbury, Joshua L Johnson, Gregory A Petsko, Dagmar Ringe

Proteomics· May 2014

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