Publications by authors named "Jared Spidel"

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Efficient Production of Homogeneous Lysine-Based Antibody Conjugates Using Microbial Transglutaminase.
Jared L Spidel, Earl F Albone

Methods Mol Biol· April 2020

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Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease.
Malcolm Roberts, Ioanna Sevastou, Yoichi Imaizumi, Kavita Mistry, Sonia Talma, Jared Spidel

Acta Neuropathol Commun· February 2020

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Implementation of Plate Imaging for Demonstration of Monoclonality in Biologics Manufacturing Development.
Kyle Zingaro, David Shaw, Jerry Carson, Anke Mayer-Bartschmid, Christian Bender, Jared Spidel

PDA J Pharm Sci Technol· May 2019

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Site-Specific Conjugation to Native and Engineered Lysines in Human Immunoglobulins by Microbial Transglutaminase.
Jared L Spidel, Benjamin Vaessen, Earl F Albone, Xin Cheng, Arielle Verdi

Bioconjug Chem· September 2017

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Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus.
Earl F Albone, Jared L Spidel, Xin Cheng, Young Chul Park, Sara Jacob

Cancer Biol Ther· May 2017

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Engineering humanized antibody framework sequences for optimal site-specific conjugation of cytotoxins.
Jared L Spidel, Earl F Albone, Xin Cheng, Benjamin Vaessen, Sara Jacob

MAbs· May 2017

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Rapid high-throughput cloning and stable expression of antibodies in HEK293 cells.
Jared L Spidel, Benjamin Vaessen, Yin Yin Chan, Luigi Grasso, J Bradford Kline

J Immunol Methods· December 2016

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The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity.
JianMin Lin, Jared L Spidel, Christopher J Maddage, Katherine A Rybinski, Rina P Kennedy

Cancer Biol Ther· November 2013

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Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B.
Brian Drozdowski, Yuhong Zhou, Brad Kline, Jared Spidel, Yin Yin Chan

J Immune Based Ther Vaccines· December 2010

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Genetic Studies of the beta-hairpin loop of Rous sarcoma virus capsid protein.
Jared L Spidel, Carol B Wilson, Rebecca C Craven, John W Wills

J Virol· February 2007

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The C-terminal half of TSG101 blocks Rous sarcoma virus budding and sequesters Gag into unique nonendosomal structures.
Marc C Johnson, Jared L Spidel, Danso Ako-Adjei, John W Wills, Volker M Vogt

J Virol· March 2005

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Lysines close to the Rous sarcoma virus late domain critical for budding.
Jared L Spidel, Rebecca C Craven, Carol B Wilson, Akash Patnaik, Huating Wang

J Virol· October 2004

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Kinetic and docking studies of the interaction of quinones with the quinone reductase active site.
Zhigang Zhou, Derek Fisher, Jared Spidel, Jodi Greenfield, Brian Patson

Biochemistry· February 2003

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