Publications by authors named "Jared Toettcher"

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Depth-enhanced molecular imaging with two-photon oblique plane microscopy.
Kevin Keomanee-Dizon, Yaakov Clenman, Alejandra Duran, Sergey Ryabichko, Pauline Hansen, Jared E Toettcher

ArXiv· December 2025

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Live imaging endogenous transcription factor dynamics reveals mechanisms of epiblast and primitive endoderm fate segregation.
Rebecca P Kim-Yip, David Denberg, Denis F Faerberg, Hayden Nunley, Isabella Leite, Jared Toettcher

Curr Biol· September 2025

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PyCLM: programming-free, closed-loop microscopy for real-time measurement, segmentation, and optogenetic stimulation.
Harrison R Oatman, Beena C Lad, Jared Toettcher

bioRxiv· September 2025

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A live-cell biosensor of in vivo receptor tyrosine kinase activity reveals feedback regulation of a developmental gradient.
Emily K Ho, Rebecca P Kim-Yip, Alison G Simpkins, Payam E Farahani, Harrison R Oatman, Jared E Toettcher

Cell Rep· July 2025

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Large-scale control over collective cell migration using light-activated epidermal growth factor receptors.
Kevin Suh, Richard H Thornton, Long Nguyen, Payam E Farahani, Daniel J Cohen, Jared E Toettcher

Cell Syst· March 2025

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CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration.
Ankita Jha, Ankit Chandra, Payam Farahani, Jared Toettcher, Jason M Haugh

bioRxiv· January 2025

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measurements of receptor tyrosine kinase activity reveal feedback regulation of a developmental gradient.
Emily K Ho, Rebecca P Kim-Yip, Alison G Simpkins, Payam E Farahani, Harrison R Oatman, Jared E Toettcher

bioRxiv· January 2025

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Efficient prime editing in two-cell mouse embryos using PEmbryo.
Rebecca P Kim-Yip, Ryan McNulty, Bradley Joyce, Antonio Mollica, Peter J Chen, Jared E Toettcher

Nat Biotechnol· December 2024

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Recording morphogen signals reveals mechanisms underlying gastruloid symmetry breaking.
Harold M McNamara, Sabrina C Solley, Britt Adamson, Michelle M Chan, Jared E Toettcher

Nat Cell Biol· November 2024

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Engineered chimeric receptors for dissecting interferon signaling.
Aaron E Lin, Emily V Mesev, Jared E Toettcher, Alexander Ploss

J Virol· October 2024

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Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag.
Ellen H Brumbaugh-Reed, Yang Gao, Kazuhiro Aoki, Jared E Toettcher

Nat Commun· August 2024

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Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing.
Long T Nguyen, Noah R Rakestraw, Brianna L M Pizzano, Cullen B Young, Yujia Huang, Jared E Toettcher

bioRxiv· July 2024

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Large-scale control over collective cell migration using light-controlled epidermal growth factor receptors.
Kevin Suh, Richard Thornton, Payam E Farahani, Daniel Cohen, Jared Toettcher

bioRxiv· May 2024

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Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag.
Ellen H Brumbaugh-Reed, Kazuhiro Aoki, Jared E Toettcher

bioRxiv· January 2024

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Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors.
Emily V Mesev, Aaron E Lin, Emma G Guare, Brigitte L Heller, Florian Douam, Jared E Toettcher

Sci Signal· October 2023

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Dynamics of an incoherent feedforward loop drive ERK-dependent pattern formation in the early Drosophila embryo.
Emily K Ho, Harrison R Oatman, Sarah E McFann, Liu Yang, Heath E Johnson, Jared E Toettcher

Development· September 2023

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Synthetic Heterodimers of Type III Interferon Receptors Require TYK2 for STAT Activation.
Emily V Mesev, Emma G Guare, Alexander Ploss, Jared E Toettcher

J Interferon Cytokine Res· September 2023

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Control of gastruloid patterning and morphogenesis by the Erk and Akt signaling pathways.
Evan J Underhill, Jared E Toettcher

Development· August 2023

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Light-switchable transcription factors obtained by direct screening in mammalian cells.
Liyuan Zhu, Harold M McNamara, Jared E Toettcher

Nat Commun· June 2023

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Recording morphogen signals reveals origins of gastruloid symmetry breaking.
Harold M McNamara, Sabrina C Solley, Britt Adamson, Michelle M Chan, Jared E Toettcher

bioRxiv· June 2023

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Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems.
Harold M McNamara, Beatrice Ramm, Jared E Toettcher

Semin Cell Dev Biol· May 2023

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pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells.
Payam E Farahani, Xiaoyu Yang, Emily V Mesev, Kaylan A Fomby, Ellen H Brumbaugh-Reed, Jared E Toettcher

Elife· May 2023

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Dynamics of an incoherent feedforward loop drive ERK-dependent pattern formation in the early embryo.
Emily K Ho, Harrison R Oatman, Sarah E McFann, Liu Yang, Heath E Johnson, Jared E Toettcher

bioRxiv· March 2023

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Putting in the Erk: Growth factor signaling and mesoderm morphogenesis.
Sarah E McFann, Stanislav Y Shvartsman, Jared E Toettcher

Curr Top Dev Biol· May 2022

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Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation.
Anand P Singh, Ping Wu, Sergey Ryabichko, João Raimundo, Michael Swan, Jared E Toettcher

Cell Rep· March 2022

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