Publications by authors named "Jasim Al-Rawi"

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Synthesis and biological evaluation of 4H-benzo[e][1,3]oxazin-4-ones analogues of TGX-221 as inhibitors of PI3Kβ.
Ehtesham U R Mohammed, Zoe J Porter, Ian G Jennings, Jasim M A Al-Rawi, Philip E Thompson

Bioorg Med Chem· September 2022

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Inhibition of AKT signalling by benzoxazine derivative LTUR6 through the modulation of downstream kinases.
Rejitha Suraj, Jasim Al-Rawi, Christopher Bradley

Invest New Drugs· August 2019

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Synthesis and biological evaluation of 8-aryl-2-morpholino-7-O-substituted benzo[e][1,3]oxazin-4-ones against DNA-PK, PI3K, PDE3A enzymes and platelet aggregation.
Md Saifuzzaman, Rick Morrison, Zhaohua Zheng, Stephanie Orive, Justin Hamilton, Jasim M A Al-Rawi

Bioorg Med Chem· October 2017

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Synthesis, structure elucidation, DNA-PK, PI3K, anti-platelet and anti-bacteria activity of linear 5, 6, and 10-substituted-2-morpholino-chromen-oxazine-dione and angular 3, 4, 6-substituted-8-morpholino-chromen-oxazine-2,10-dione.
Rick Morrison, Jasim M A Al-Rawi

J Enzyme Inhib Med Chem· February 2017

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Synthesis of linear and angular aryl-morpholino-naphth-oxazines, their DNA-PK, PI3K, PDE3A and antiplatelet activity.
Rick Morrison, Zhaohua Zheng, Ian G Jennings, Philip E Thompson, Jasim M A Al-Rawi

Bioorg Med Chem Lett· November 2016

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Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines.
Rick Morrison, Jasim M A Al-Rawi, Ian G Jennings, Philip E Thompson, Michael J Angove

Eur J Med Chem· March 2016

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Novel benzoxazines as inhibitors of angiogenesis.
Sara Al-Rawi, Terri Meehan-Andrews, Chris Bradley, Jasim Al-Rawi

Invest New Drugs· February 2015

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Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines.
Tyson Belz, Saleh Ihmaid, Jasim Al-Rawi, Steve Petrovski

Int J Med Chem· November 2014

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Radiosensitizing activity of a novel Benzoxazine through the promotion of apoptosis and inhibition of DNA repair.
Suraj Radhamani, Christopher Bradley, Terri Meehan-Andrews, Saleh K Ihmaid, Jasim Al-Rawi

Invest New Drugs· June 2014

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Chemo-sensitisation of HeLa cells to etoposide by a benzoxazine in the absence of DNA-PK inhibition.
Cheree Fitzgibbon, Saleh Ihmaid, Jasim Al-Rawi, Terri Meehan-Andrews, Christopher Bradley

Invest New Drugs· December 2013

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Synthesis, DNA-PK inhibition, anti-platelet activity studies of 2-(N-substituted-3-aminopyridine)-substituted-1,3-benzoxazines and DNA-PK and PI3K inhibition, homology modelling studies of 2-morpholino-(7,8-di and 8-substituted)-1,3-benzoxazines.
Saleh K Ihmaid, Jasim M A Al-Rawi, Christopher J Bradley, Michael J Angove, Murray N Robertson

Eur J Med Chem· November 2012

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Synthesis, structural elucidation, DNA-PK inhibition, homology modelling and anti-platelet activity of morpholino-substituted-1,3-naphth-oxazines.
Saleh Ihmaid, Jasim Al-Rawi, Christopher Bradley, Michael J Angove, Murray N Robertson

Bioorg Med Chem· July 2011

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Synthesis, structural elucidation and DNA-dependant protein kinase and antiplatelet studies of 2-amino-[5, 6, 7, 8-mono and 7, 8-di-substituted]-1,3-benzoxazines.
Saleh Ihmaid, Jasim Al-Rawi, Christopher Bradley

Eur J Med Chem· November 2010

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Synthesis, identification and antiplatelet evaluation of 2-morpholino substituted benzoxazines.
Kaylene M Pritchard, Jasim Al-Rawi, Christopher Bradley

Eur J Med Chem· September 2007

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