Publications by authors named "Jason A Gilbert"

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Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis.
Simina Ticau, Gautham V Sridharan, Shira Tsour, William L Cantley, Amy Chan, Jason A Gilbert, David Erbe, Emre Aldinc, Mary M Reilly, David Adams

Neurology· January 2021

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Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3' End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain.
Rajat S Das, Dhrubajyoti Datta, Christopher R Brown, Jason A Gilbert, Amy Chan

J Med Chem· February 2025

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Improved Metabolic Stability and Silencing Efficacy of siRNAs with Phosphorothioate Linkage-Free, GalNAc-Conjugated Sense Strands Containing Morpholino-LNA Modifications.
Dhrubajyoti Datta, Pawan Kumar, Jayanta Kundu, June Qin, Jason A Gilbert

Org Lett· November 2024

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Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.
Shigeo Matsuda, Saikat Bala, Jen-Yu Liao, Dhrubajyoti Datta, Atsushi Mikami, Jason A Gilbert

J Am Chem Soc· September 2023

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Metabolically Stable Anomeric Linkages Containing GalNAc-siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways.
Pachamuthu Kandasamy, Shohei Mori, Shigeo Matsuda, Namrata Erande, Dhrubajyoti Datta, Jason A Gilbert

J Med Chem· February 2023

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Role of a "Magic" Methyl: 2'-Deoxy-2'-α-F-2'-β--methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5'-Phosphate Mimics and Mitigation of Off-Target Effects.
Dale C Guenther, Shohei Mori, Shigeo Matsuda, Jason A Gilbert, Jennifer L S Willoughby

J Am Chem Soc· August 2022

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siRNAs containing 2'-fluorinated Northern-methanocarbacyclic (2'-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2'-F-NMC NTPs.
Masaaki Akabane-Nakata, Namrata D Erande, Pawan Kumar, Rohan Degaonkar, Jason A Gilbert

Nucleic Acids Res· March 2021

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Constraining Solar Wind Heating Processes by Kinetic Properties of Heavy Ions.
Patrick J Tracy, Justin C Kasper, Jim M Raines, Paul Shearer, Jason A Gilbert

Phys Rev Lett· June 2016

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GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.
Marc A Egerman, Samuel M Cadena, Jason A Gilbert, Angelika Meyer, Hallie N Nelson

Cell Metab· July 2015

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An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis.
Zhizhong Li, Jason A Gilbert, Yunyu Zhang, Minsi Zhang, Qiong Qiu

Dev Cell· December 2012

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MESSENGER observations of the spatial distribution of planetary ions near Mercury.
Thomas H Zurbuchen, Jim M Raines, James A Slavin, Daniel J Gershman, Jason A Gilbert

Science· September 2011

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