Publications by authors named "Jason A Koutcher"

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Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma.
Evan K Noch, Laura N Palma, Isaiah Yim, Nayah Bullen, Yuqing Qiu, Jason A Koutcher

Neuro Oncol· December 2023

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Multimodal imaging of metabolic activities for distinguishing subtypes of breast cancer.
Zhi Li, Chloe Nguyen, Hongje Jang, David Hoang, SoeSu Min, Jason A Koutcher

Biomed Opt Express· November 2023

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CTLA-4 blockade drives loss of T stability in glycolysis-low tumours.
Roberta Zappasodi, Inna Serganova, Ivan J Cohen, Masatomo Maeda, Masahiro Shindo, Jason A Koutcher

Nature· March 2021

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Lactate Dehydrogenase A Depletion Alters MyC-CaP Tumor Metabolism, Microenvironment, and CAR T Cell Therapy.
Mayuresh M Mane, Ivan J Cohen, Ellen Ackerstaff, Khalid Shalaby, Jenny N Ijoma, Jason A Koutcher

Mol Ther Oncolytics· September 2020

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Distinguishing metastatic triple-negative breast cancer from nonmetastatic breast cancer using second harmonic generation imaging and resonance Raman spectroscopy.
Ethan Bendau, Jason Smith, Lin Zhang, Ellen Ackerstaff, Natalia Kruchevsky, Jason A Koutcher

J Biophotonics· July 2020

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Quantification of Nanoparticle Enhancement in Polarized Breast Tumor Macrophage Deposits by Spatial Analysis of MRI and Histological Iron Contrast Using Computer Vision.
Avigdor Leftin, Jason A Koutcher

Contrast Media Mol Imaging· July 2019

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LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response.
Inna Serganova, Ivan J Cohen, Kiranmayi Vemuri, Masahiro Shindo, Masatomo Maeda, Jason A Koutcher

PLoS One· March 2019

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Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury.
Sahra Bodo, Cécile Campagne, Tin Htwe Thin, Daniel S Higginson, H Alberto Vargas, Jason A Koutcher

J Clin Invest· February 2019

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Imaging endogenous macrophage iron deposits reveals a metabolic biomarker of polarized tumor macrophage infiltration and response to CSF1R breast cancer immunotherapy.
Avigdor Leftin, Nir Ben-Chetrit, Johanna A Joyce, Jason A Koutcher

Sci Rep· January 2019

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Automation of pattern recognition analysis of dynamic contrast-enhanced MRI data to characterize intratumoral vascular heterogeneity.
SoHyun Han, Radka Stoyanova, Hansol Lee, Sean D Carlin, Jason A Koutcher

Magn Reson Med· March 2018

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Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer.
Avigdor Leftin, Nir Ben-Chetrit, Florian Klemm, Johanna A Joyce, Jason A Koutcher

PLoS One· October 2017

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Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer.
Avigdor Leftin, Huiyong Zhao, Mesru Turkekul, Elisa de Stanchina, Katia Manova, Jason A Koutcher

Sci Rep· September 2017

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Inhibition of prostate cancer proliferation by Deferiprone.
Rui V Simões, Suresh Veeraperumal, Inna S Serganova, Natalia Kruchevsky, Joseph Varshavsky, Jason A Koutcher

NMR Biomed· June 2017

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Tumor stroma interaction is mediated by monocarboxylate metabolism.
Brijesh B Patel, Ellen Ackerstaff, Inna S Serganova, John E Kerrigan, Ronald G Blasberg, Jason A Koutcher

Exp Cell Res· March 2017

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The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma.
Amrita M Nargund, Can G Pham, Yiyu Dong, Patricia I Wang, Hatice U Osmangeyoglu, Jason A Koutcher

Cell Rep· March 2017

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Corrigendum to "Noninvasive Multimodality Imaging of the Tumor Microenvironment: Registered Dynamic Magnetic Resonance Imaging and Positron Emission Tomography Studies of a Preclinical Tumor Model of Tumor Hypoxia" [Neoplasia 11 (2009) 247-259].
HyungJoon Cho, Ellen Ackerstaff, Sean Carlin, Mihaela E Lupu, Ya Wang, Jason A Koutcher

Neoplasia· December 2016

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Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment.
Xiaorong Sun, Ellen Ackerstaff, Fuqiu He, Ligang Xing, Hung Tsung Hsiao, Jason A Koutcher

Oncotarget· October 2015

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Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment.
Rui V Simões, Inna S Serganova, Natalia Kruchevsky, Avigdor Leftin, Alexander A Shestov, Jason A Koutcher

Neoplasia· August 2015

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Anatomic segmentation improves prostate cancer detection with artificial neural networks analysis of 1H magnetic resonance spectroscopic imaging.
Lukasz Matulewicz, Jacobus F A Jansen, Louisa Bokacheva, Hebert Alberto Vargas, Oguz Akin, Jason A Koutcher

J Magn Reson Imaging· December 2014

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Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer.
Nerissa Therese Viola-Villegas, Sean D Carlin, Ellen Ackerstaff, Kuntal K Sevak, Vadim Divilov, Jason A Koutcher

Proc Natl Acad Sci U S A· May 2014

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High-field small animal magnetic resonance oncology studies.
Louisa Bokacheva, Ellen Ackerstaff, H Carl LeKaye, Kristen Zakian, Jason A Koutcher

Phys Med Biol· January 2014

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Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors.
Asif Rizwan, Inna Serganova, Raya Khanin, Hazem Karabeber, Xiaohui Ni, Jason A Koutcher

Clin Cancer Res· September 2013

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ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.
Alvaro Aytes, Antonina Mitrofanova, Carolyn Waugh Kinkade, Celine Lefebvre, Ming Lei, Jason A Koutcher

Proc Natl Acad Sci U S A· September 2013

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Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma.
Fernando Arias-Mendoza, Geoffrey S Payne, Kristen Zakian, Marion Stubbs, Owen A O'Connor, Jason A Koutcher

Acad Radiol· September 2013

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Native fluorescence spectroscopy reveals spectral differences among prostate cancer cell lines with different risk levels.
Yang Pu, Jianpeng Xue, Wubao Wang, Baogang Xu, Yueqing Gu, Jason A Koutcher

J Biomed Opt· August 2013

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