Publications by authors named "Jason A Mears"

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Conformational Rearrangement of Fission DSPs.
Anelise N Hutson, Kristy Rochon, Jason A Mears

Bioessays· November 2025

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The Structure of the Drp1 Lattice on Membrane.
Ruizhi Peng, Kristy Rochon, Anelise N Hutson, Scott M Stagg, Jason A Mears

J Mol Biol· June 2025

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Fis1 regulates mitochondrial morphology, bioenergetics and removal of mitochondrial DNA damage in irradiated glioblastoma cells.
Yuli Buckley, Maria S K Stoll, Charles L Hoppel, Jason A Mears

J Cell Sci· May 2025

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The Structure of the Drp1 Lattice on Membrane.
Ruizhi Peng, Kristy Rochon, Anelise N Hutson, Scott M Stagg, Jason A Mears

bioRxiv· February 2025

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Mitochondrial biology: Unique membrane remodeling from the matrix.
Jason A Mears

Curr Biol· June 2024

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Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1.
Kristy Rochon, Brianna L Bauer, Nathaniel A Roethler, Yuli Buckley, Chih-Chia Su, Jason A Mears

Nat Commun· February 2024

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Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif.
Isabel Pérez-Jover, Kristy Rochon, Di Hu, Mukesh Mahajan, Pooja Madan Mohan, Jason A Mears

Nat Commun· January 2024

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High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
Zhemin Zhang, Marios L Tringides, Christopher E Morgan, Masaru Miyagi, Jason A Mears

Mol Cell Proteomics· December 2023

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Allosteric control of dynamin-related protein 1-catalyzed mitochondrial fission through a conserved disordered C-terminal Short Linear Motif.
Isabel Pérez-Jover, Kristy Rochon, Di Hu, Pooja Madan Mohan, Isaac Santos-Perez, Jason A Mears

Res Sq· July 2023

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Disease-associated mutations in Drp1 have fundamentally different effects on the mitochondrial fission machinery.
Brianna L Bauer, Kristy Rochon, Jasmine C Liu, Rajesh Ramachandran, Jason A Mears

Hum Mol Genet· June 2023

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GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
Dionysios C Watson, Defne Bayik, Simon Storevik, Shannon Sherwin Moreino, Samuel A Sprowls, Jason A Mears

Nat Cancer· May 2023

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DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs.
Gabriella L Robertson, Stellan Riffle, Mira Patel, Caroline Bodnya, Andrea Marshall, Jason A Mears

J Cell Sci· February 2023

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Drp1 and the cytoskeleton: mechanistic nexus in mitochondrial division.
Jason A Mears, Rajesh Ramachandran

Curr Opin Physiol· October 2022

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Solvent accessibility of E1α and E1β residues with known missense mutations causing pyruvate dehydrogenase complex (PDC) deficiency: Impact on PDC-E1 structure and function.
Nicole H Ducich, Jason A Mears, Jirair K Bedoyan

J Inherit Metab Dis· May 2022

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Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass.
Elizabeth O Akinbiyi, Lara K Abramowitz, Brianna L Bauer, Maria S K Stoll, Charles L Hoppel, Jason A Mears

Sci Rep· November 2021

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A structure and function relationship study to identify the impact of the R721G mutation in the human mitochondrial lon protease.
Zhou Sha, Monica M Montano, Kristy Rochon, Jason A Mears, Daniel Deredge

Arch Biochem Biophys· October 2021

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Affinity Purification and Functional Characterization of Dynamin-Related Protein 1.
Ryan W Clinton, Brianna L Bauer, Jason A Mears

Methods Mol Biol· March 2021

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In vitro and in vivo assays for mitochondrial fission and fusion.
Suzanne Hoppins, Laura L Lackner, Jason E Lee, Jason A Mears

Methods Cell Biol· December 2020

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GFP fluorescence tagging alters dynamin-related protein 1 oligomerization dynamics and creates disassembly-refractory puncta to mediate mitochondrial fission.
Felipe Montecinos-Franjola, Brianna L Bauer, Jason A Mears, Rajesh Ramachandran

Sci Rep· September 2020

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Mitochondrial Dysfunction in Primary Ovarian Insufficiency.
Dov Tiosano, Jason A Mears, David A Buchner

Endocrinology· October 2019

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Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission.
Bin Lu, Bridget Kennedy, Ryan W Clinton, Emily Jue Wang, Daniel McHugh, Jason A Mears

Sci Rep· July 2018

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Morphological Pathways of Mitochondrial Division.
Bernard Tandler, Charles L Hoppel, Jason A Mears

Antioxidants (Basel)· February 2018

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Cryo-EM Studies of Drp1 Reveal Cardiolipin Interactions that Activate the Helical Oligomer.
Christopher A Francy, Ryan W Clinton, Chris Fröhlich, Colleen Murphy, Jason A Mears

Sci Rep· September 2017

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Using Scaffold Liposomes to Reconstitute Lipid-proximal Protein-protein Interactions In Vitro.
Ryan W Clinton, Jason A Mears

J Vis Exp· January 2017

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Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor.
Ryan W Clinton, Christopher A Francy, Rajesh Ramachandran, Xin Qi, Jason A Mears

J Biol Chem· January 2016

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