Publications by authors named "Jason A Sprowl"

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Regulation of hepatic organic anion transporting polypeptide 1B-type transport function by the protein kinase LYN.
Vivian Xu, Mahesh R Nepal, Eman Ahmed, Benjamin D Kaczynski, Yue Xu, Jason A Sprowl

Drug Metab Dispos· September 2025

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Coproporphyrin I as an in vitro fluorescent probe to measure OATP1B1 transport activity.
Elizabeth R Hayden, Vivian Xu, Lisa Krotz, Jessica J Hockler, Benjamin D Kaczynski, Jason A Sprowl

Drug Metab Dispos· May 2025

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Impact of Drug-Mediated Inhibition of Intestinal Transporters on Nutrient and Endogenous Substrate Disposition…an Afterthought?
Kshitee Kharve, Andrew S Engley, Mary F Paine, Jason A Sprowl

Pharmaceutics· March 2024

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Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium.
Kim L R Brouwer, Raymond Evers, Elizabeth Hayden, Shuiying Hu, Cindy Yanfei Li, Jason A Sprowl

Clin Pharmacol Ther· September 2022

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Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake.
Vusumuzi N Hove, Kenneth Anderson, Elizabeth R Hayden, Kyle Z Pasquariello, Alice A Gibson, Jason A Sprowl

Mol Pharmacol· June 2022

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Current Understanding of Membrane Transporters as Regulators or Targets for Cisplatin-Induced Hearing Loss.
Kyle Z Pasquariello, Jason M Dey, Jason A Sprowl

Mol Pharmacol· October 2021

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Regulation of OATP1B1 Function by Tyrosine Kinase-mediated Phosphorylation.
Elizabeth R Hayden, Mingqing Chen, Kyle Z Pasquariello, Alice A Gibson, James J Petti, Jason A Sprowl

Clin Cancer Res· August 2021

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Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.
Kevin M Huang, Alix F Leblanc, Muhammad Erfan Uddin, Ji Young Kim, Mingqing Chen, Jason A Sprowl

J Clin Invest· September 2020

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Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium.
Raymond Evers, Micheline Piquette-Miller, Joseph W Polli, Frans G M Russel, Jason A Sprowl

Clin Pharmacol Ther· November 2018

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Strategies to Reduce Solute Carrier-Mediated Toxicity.
Shuiying Hu, Jason A Sprowl

Clin Pharmacol Ther· November 2018

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OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.
Alix F Leblanc, Jason A Sprowl, Paola Alberti, Alessia Chiorazzi, W David Arnold

J Clin Invest· February 2018

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A phosphotyrosine switch regulates organic cation transporters.
Jason A Sprowl, Su Sien Ong, Alice A Gibson, Shuiying Hu, Guoqing Du

Nat Commun· March 2016

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Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity.
Claudia Lanvers-Kaminsky, Jason A Sprowl, Ingrid Malath, Dirk Deuster, Maria Eveslage

Pharmacogenomics· January 2016

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Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions.
Navjotsingh Pabla, Alice A Gibson, Mike Buege, Su Sien Ong, Lie Li, Jason A Sprowl

Proc Natl Acad Sci U S A· April 2015

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Cisplatin-induced renal injury is independently mediated by OCT2 and p53.
Jason A Sprowl, Cynthia S Lancaster, Navjotsingh Pabla, Edwin Hermann, Ashley M Kosloske

Clin Cancer Res· August 2014

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Uptake carriers and oncology drug safety.
Jason A Sprowl, Alex Sparreboom

Drug Metab Dispos· April 2014

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Can erlotinib ameliorate cisplatin-induced toxicities?
Jason A Sprowl, Ron H Mathijssen, Alex Sparreboom

J Clin Oncol· September 2013

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Polymorphic transporters and platinum pharmacodynamics.
Jason A Sprowl, Rachel A Ness, Alex Sparreboom

Drug Metab Pharmacokinet· August 2013

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Modulation of OATP1B-type transporter function alters cellular uptake and disposition of platinum chemotherapeutics.
Cynthia S Lancaster, Jason A Sprowl, Aisha L Walker, Shuiying Hu, Alice A Gibson

Mol Cancer Ther· August 2013

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2.
Jason A Sprowl, Giuliano Ciarimboli, Cynthia S Lancaster, Hugh Giovinazzo, Alice A Gibson

Proc Natl Acad Sci U S A· July 2013

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CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.
Anne-Joy M de Graan, Laure Elens, Jason A Sprowl, Alex Sparreboom, Lena E Friberg

Clin Cancer Res· June 2013

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Contribution of tumoral and host solute carriers to clinical drug response.
Jason A Sprowl, Torben S Mikkelsen, Hugh Giovinazzo, Alex Sparreboom

Drug Resist Updat· August 2012

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Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization.
Allan D Heibein, Baoqing Guo, Jason A Sprowl, David A Maclean, Amadeo M Parissenti

BMC Cancer· August 2012

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Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients.
Giuliano Ciarimboli, Cynthia S Lancaster, Eberhard Schlatter, Ryan M Franke, Jason A Sprowl

Clin Cancer Res· February 2012

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Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.
Jason A Sprowl, Kerry Reed, Stephen R Armstrong, Carita Lanner, Baoqing Guo

Breast Cancer Res· January 2012

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