Publications by authors named "Jason Botten"

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Specific and versatile monoclonal antibodies for hantavirus research.
Autumn LaPointe, Kimberly Martinez, Christina Shou, Inessa Manuelyan, Jason Botten

mSphere· December 2025

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Specific and versatile monoclonal antibodies for hantavirus research.
Autumn LaPointe, Kimberly Martinez, Christina Shou, Inessa Manuelyan, Jason Botten

bioRxiv· September 2025

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Polyclonal B cells acquire LCMV antigens in a GP1-dependent manner.
Gabriel Chamberlain, Guillaume L Lopez, Léa Bourguignon, Xavier Laulhé, Yasmine Adda-Bouchard, Jason W Botten

PLoS Pathog· July 2025

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SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies.
Hailong Guo, Sha Ha, Jason W Botten, Kai Xu, Ningyan Zhang

Viruses· April 2024

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An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV.
Hailong Guo, Bomsoo Cho, Paul R Hinton, Sijia He, Yongjun Yu, Jason W Botten

Emerg Microbes Infect· December 2023

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Clinical Performance Characteristics of the Swift Normalase Amplicon Panel for Sensitive Recovery of Severe Acute Respiratory Syndrome Coronavirus 2 Genomes.
Lasata Shrestha, Michelle J Lin, Hong Xie, Margaret G Mills, Shah A Mohamed Bakhash, Jason W Botten

J Mol Diagn· September 2022

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Predicting infectivity: comparing four PCR-based assays to detect culturable SARS-CoV-2 in clinical samples.
Emily A Bruce, Margaret G Mills, Reigran Sampoleo, Garrett A Perchetti, Meei-Li Huang, Jason W Botten

EMBO Mol Med· February 2022

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An international, interlaboratory ring trial confirms the feasibility of an extraction-less "direct" RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples.
Margaret G Mills, Emily Bruce, Meei-Li Huang, Jessica W Crothers, Ollivier Hyrien, Jason Botten

PLoS One· January 2022

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SARS-CoV-2 triggers DNA damage response in Vero E6 cells.
Joshua Victor, Jamie Deutsch, Annalis Whitaker, Erica N Lamkin, Anthony March, Jason W Botten

Biochem Biophys Res Commun· November 2021

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Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen.
Ilona Rissanen, Stefanie A Krumm, Robert Stass, Annalis Whitaker, James E Voss, Jason W Botten

mBio· August 2021

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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Nir Drayman, Jennifer K DeMarco, Krysten A Jones, Saara-Anne Azizi, Heather M Froggatt, Jason W Botten

Science· August 2021

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Comparison of VSV Pseudovirus and Focus Reduction Neutralization Assays for Measurement of Anti- Neutralizing Antibodies in Patient Samples.
Cecilia Vial, Annalis Whitaker, Jan Wilhelm, Jimena Ovalle, Ruth Perez, Jason W Botten

Front Cell Infect Microbiol· June 2021

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Laboratory Worker Self-Contamination with Noninfectious SARS-CoV-2 DNA Can Result in False-Positive Reverse Transcriptase PCR-Based Surveillance Testing.
Theresa L Montgomery, Michelle Paavola, Emily A Bruce, Jason W Botten, Jessica W Crothers

J Clin Microbiol· June 2021

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An international, interlaboratory ring trial confirms the feasibility of an open-source, extraction-less "direct" RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples.
Margaret G Mills, Emily Bruce, Meei-Li Huang, Jessica W Crothers, Ollivier Hyrien, Jason Botten

medRxiv· April 2021

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Rapid Induction and Maintenance of Virus-Specific CD8 T and CD4 T Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans.
Nancy Graham, Phil Eisenhauer, Sean A Diehl, Kristen K Pierce, Stephen S Whitehead, Jason W Botten

Front Immunol· March 2021

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Stimulation of B Cell Immunity in Flavivirus-Naive Individuals by the Tetravalent Live Attenuated Dengue Vaccine TV003.
Huy A Tu, Usha K Nivarthi, Nancy R Graham, Philip Eisenhauer, Matthew J Delacruz, Jason W Botten

Cell Rep Med· December 2020

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SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.
Abhik K Banerjee, Mario R Blanco, Emily A Bruce, Drew D Honson, Linlin M Chen, Jason W Botten

Cell· November 2020

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Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step.
Emily A Bruce, Meei-Li Huang, Garrett A Perchetti, Scott Tighe, Pheobe Laaguiby, Jason W Botten

PLoS Biol· October 2020

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Kinetics and isotype assessment of antibodies targeting the spike protein receptor-binding domain of severe acute respiratory syndrome-coronavirus-2 in COVID-19 patients as a function of age, biological sex and disease severity.
Nancy R Graham, Annalis N Whitaker, Camilla A Strother, Ashley K Miles, Dore Grier, Jason W Botten

Clin Transl Immunology· October 2020

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Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 .
Nir Drayman, Krysten A Jones, Saara-Anne Azizi, Heather M Froggatt, Kemin Tan, Jason W Botten

bioRxiv· September 2020

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Defective Interfering Particles of Negative-Strand RNA Viruses.
Christopher M Ziegler, Jason W Botten

Trends Microbiol· July 2020

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Kinetics and Isotype Assessment of Antibodies Targeting the Spike Protein Receptor Binding Domain of SARS-CoV-2 In COVID-19 Patients as a function of Age and Biological Sex.
Nancy R Graham, Annalis N Whitaker, Camilla A Strother, Ashley K Miles, Dore Grier, Jason W Botten

medRxiv· July 2020

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'All In': a pragmatic framework for COVID-19 testing and action on a global scale.
Syril D Pettit, Keith R Jerome, David Rouquié, Bernard Mari, Pascal Barbry, Jason W Botten

EMBO Mol Med· June 2020

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Meeting report: Eleventh International Conference on Hantaviruses.
Jan Clement, Clas Ahlm, Tatjana Avšič-Županc, Jason Botten, Kartik Chandran

Antiviral Res· April 2020

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DIRECT RT-qPCR DETECTION OF SARS-CoV-2 RNA FROM PATIENT NASOPHARYNGEAL SWABS WITHOUT AN RNA EXTRACTION STEP.
Emily A Bruce, Meei-Li Huang, Garrett A Perchetti, Scott Tighe, Pheobe Laaguiby, Jason W Botten

bioRxiv· April 2020

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