Publications by authors named "Jason Brenchley"

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Differentiated Thyroid Cancer Is Associated With Sex-specific Immune Response.
Leila Shobab, Jennifer Simpson, Matthew McCoy, Hui Zheng, Sonam Kumari, Jason M Brenchley

J Endocr Soc· January 2026

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A de novo dominant-negative PSMB8 mutation causes severe CANDLE/PRAAS due to arrested proteasome biogenesis.
Sophie Wolfgramm, Sara Alehashemi, Martin Wendlandt, Franziska G Thiel, Adriana A de Jesus, Jason M Brenchley

Ann Rheum Dis· November 2025

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Repeated enema administration in rhesus macaques is not sufficient to promote bacterial dysbiosis or gastrointestinal dysfunction.
Alexandra M Ortiz, Fabiola Castello Casta, Elizabeth G Bodykevich, Jacob K Flynn, Christine M Fennessey, Jason M Brenchley

Mucosal Immunol· October 2025

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Hematological Consequences of Environmental Change During Dewilding of Rhesus Macaques.
P'ng Loke, Annabelle Smith, Kasalina Kiwanuka, Gabriela Pessenda, Andrew Rahmberg, Jason Brenchley

Res Sq· October 2025

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Oropouche virus efficiently replicates and is immunostimulatory in vivo in nonhuman primate species.
Debra S Yee, Jonathan P Davies, Laura A VanBlargan, Andrew R Rahmberg, Katherine E Burgomaster, Jason M Brenchley

Sci Adv· September 2025

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Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primates.
Ahmed A Belghith, Catherine A Cotter, Maxinne A Ignacio, Patricia L Earl, Rory A Hills, Jason M Brenchley

Nat Commun· May 2025

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Interaction of the endogenous antibody response with activating FcγRs enhance control of Mayaro virus through monocytes.
Megan M Dunagan, Nathânia Dábilla, Colton McNinch, Jason M Brenchley, Patrick T Dolan

PLoS Pathog· February 2025

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Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases.
Jacob K Flynn, Alexandra M Ortiz, Ivan Vujkovic-Cvijin, Hugh C Welles, Jennifer Simpson, Jason M Brenchley

Mucosal Immunol· October 2024

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SARS-CoV-2 infection perturbs the gastrointestinal tract and induces modest microbial translocation across the intestinal barrier.
Kelsie Brooks, Christine E Nelson, Cynthia Aguilar, Timothy N Hoang, Alexandra M Ortiz, Jason M Brenchley

J Virol· October 2024

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Untangling the role of the microbiome across the stages of HIV disease.
Alexandra M Ortiz, Jason M Brenchley

Curr Opin HIV AIDS· September 2024

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Multi-omics analysis of SIV-specific CD8+ T cells in multiple anatomical sites.
Jennifer Simpson, Brittany Dulek, Paul Schaughency, Jason M Brenchley

PLoS Pathog· September 2024

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Distinct SIV-specific CD8 T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.
Zachary Strongin, Laurence Raymond Marchand, Claire Deleage, M Betina Pampena, Maria Andrea Cardenas, Jason M Brenchley

Nat Immunol· July 2024

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IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques.
Christine E Nelson, Taylor W Foreman, Eduardo R Fukutani, Keith D Kauffman, Shunsuke Sakai, Jason M Brenchley

PLoS Pathog· July 2024

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Recombinant OC43 SARS-CoV-2 spike replacement virus: An improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays.
Zhe Hu, Alberto Domingo López-Muñoz, Ivan Kosik, Tiansheng Li, Victoria Callahan, Jason M Brenchley

Proc Natl Acad Sci U S A· July 2024

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Activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance.
Megan M Dunagan, Nathânia Dábilla, Colton McNinch, Jason M Brenchley, Patrick T Dolan

bioRxiv· July 2024

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SIV infection and ARV treatment reshape the transcriptional and epigenetic profile of naïve and memory T cells .
Andrew R Rahmberg, Tovah E Markowitz, Joseph C Mudd, Alexandra M Ortiz, Jason M Brenchley

J Virol· June 2024

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Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV.
Jennifer Simpson, Carly E Starke, Alexandra M Ortiz, Amy Ransier, Sam Darko, Jason M Brenchley

JCI Insight· June 2024

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From dysbiosis to defense: harnessing the gut microbiome in HIV/SIV therapy.
Jason M Brenchley, Sergio Serrano-Villar

Microbiome· June 2024

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Exacerbation of CMV and Nontuberculous Mycobacterial Infections Following PD-1 Blockade for HIV-Associated Kaposi Sarcoma.
Ifeanyichukwu U Anidi, Shunsuke Sakai, Kelsie Brooks, Steven P Fling, Michael J Wagner, Jason M Brenchley

Open Forum Infect Dis· May 2024

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Ongoing production of tissue-resident macrophages from hematopoietic stem cells in healthy adult macaques.
Andrew R Rahmberg, Chuanfeng Wu, Taehoon Shin, So Gun Hong, Luxin Pei, Jason M Brenchley

Blood Adv· February 2024

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sCD14 and Intestinal Fatty Acid Binding Protein Are Elevated in the Serum of Patients With Idiopathic Anaphylaxis.
Vivian T Cao, Melody C Carter, Jason M Brenchley, Hyejeong Bolan, Linda M Scott

J Allergy Clin Immunol Pract· July 2023

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2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques.
Alexandra M Ortiz, Fabiola Castello Casta, Andrew Rahmberg, Tovah E Markowitz, Kelsie Brooks, Jason M Brenchley

J Virol· July 2023

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Selective IgA2 deficiency in a patient with small intestinal Crohn's disease.
Pablo Canales-Herrerias, Yolanda Garcia-Carmona, Joan Shang, Hadar Meringer, Debra S Yee, Jason M Brenchley

J Clin Invest· June 2023

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The Host Adapted Fungal Pathogens of Genus Utilize Genic Regional Centromeres.
Ousmane H Cissé, Shelly Curran, H Diego Folco, Yueqin Liu, Lisa Bishop, Jason M Brenchley

bioRxiv· May 2023

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Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques.
Rachele M Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W Morrow, Alexandra M Ortiz, Jason M Brenchley

PLoS Pathog· April 2023

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