Publications by authors named "Jason C Crack"

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Cluster occupancy- and oxidation state-dependence of Yersinia enterocolitica IscR DNA binding.
Elizabeth Gray, Miaomiao Gao, Justin M Bradley, Jason C Crack, Nick E Le Brun

J Inorg Biochem· November 2025

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Yeast [FeFe]-hydrogenase-like protein Nar1 binds a [2Fe-2S] cluster.
Joseph J Braymer, Lukas Knauer, Jason C Crack, Jonathan Oltmanns, Melanie Heghmanns

Chem Sci· November 2025

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ArnR binds a [4Fe-4S] cluster and indirectly senses anaerobicity in Corynebacteria.
Jason C Crack, Lauren R Harvey, Katie E Johnson, Nick E Le Brun

Metallomics· August 2025

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Synergy of native mass spectrometry and other biophysical techniques in studies of iron‑sulfur cluster proteins and their assembly.
Jason C Crack, Nick E Le Brun

Biochim Biophys Acta Mol Cell Res· January 2025

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Polyurethane infused with heparin capped silver nanoparticles dressing for wound healing application: Synthesis, characterization and antimicrobial studies.
Jayshree H Ahire, Qi Wang, Gary Rowley, Isabelle Chambrier, Jason C Crack

Int J Biol Macromol· December 2024

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Binding of a single nitric oxide molecule is sufficient to disrupt DNA binding of the nitrosative stress regulator NsrR.
Jason C Crack, Nick E Le Brun

Chem Sci· October 2024

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CyaY and TusA regulate ISC- and SUF-mediated l-cysteine desulfurase activity.
Paolo Olivieri, Jason C Crack, Angelika Lehmann, Nick E Le Brun, Silke Leimkühler

RSC Chem Biol· September 2024

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Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway.
Paolo Olivieri, Moritz Klabes, Jason C Crack, Angelika Lehmann, Sophie P Bennett

Microbiol Spectr· July 2024

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Liquid-chromatography mass spectrometry describes post-translational modification of Shewanella outer membrane proteins.
Jessica H van Wonderen, Jason C Crack, Marcus J Edwards, Thomas A Clarke, Gerhard Saalbach

Biochim Biophys Acta Biomembr· January 2024

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From cultivation to cancer: formation of -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications.
Stephen B Stanfill, Stephen S Hecht, Andreas C Joerger, Pablo J González, Luisa B Maia, Jason C Crack

Crit Rev Toxicol· November 2023

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Stabilisation of the RirA [4Fe-4S] cluster results in loss of iron-sensing function.
Elizabeth Gray, Melissa Y Y Stewart, Libby Hanwell, Jason C Crack, Rebecca Devine

Chem Sci· September 2023

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Site-specific encoding of photoactivity and photoreactivity into antibody fragments.
Thomas Bridge, Udo Wegmann, Jason C Crack, Kate Orman, Saher A Shaikh

Nat Chem Biol· June 2023

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Native mass spectrometric studies of IscSU reveal a concerted, sulfur-initiated mechanism of iron-sulfur cluster assembly.
Sophie P Bennett, Jason C Crack, Rita Puglisi, Annalisa Pastore, Nick E Le Brun

Chem Sci· December 2022

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Reaction of Thiosulfate Dehydrogenase with a Substrate Mimic Induces Dissociation of the Cysteine Heme Ligand Giving Insights into the Mechanism of Oxidative Catalysis.
Leon P Jenner, Jason C Crack, Julia M Kurth, Zuzana Soldánová, Linda Brandt

J Am Chem Soc· October 2022

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Structural determinants of DNA recognition by the NO sensor NsrR and related Rrf2-type [FeS]-transcription factors.
Roman Rohac, Jason C Crack, Eve de Rosny, Océane Gigarel, Nick E Le Brun

Commun Biol· July 2022

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Mechanistic insights into the key marine dimethylsulfoniopropionate synthesis enzyme DsyB/DSYB.
Chun-Yang Li, Jason C Crack, Simone Newton-Payne, Andrew R J Murphy, Xiu-Lan Chen

mLife· June 2022

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The Di-Iron Protein YtfE Is a Nitric Oxide-Generating Nitrite Reductase Involved in the Management of Nitrosative Stress.
Jason C Crack, Basema K Balasiny, Sophie P Bennett, Matthew D Rolfe, Afonso Froes

J Am Chem Soc· April 2022

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Native Mass Spectrometry of Iron-Sulfur Proteins.
Jason C Crack, Nick E Le Brun

Methods Mol Biol· January 2022

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Sensing mechanisms of iron-sulfur cluster regulatory proteins elucidated using native mass spectrometry.
Jason C Crack, Elizabeth Gray, Nick E Le Brun

Dalton Trans· June 2021

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Interaction of the Wbl protein WhiD with the principal sigma factor σ depends on the WhiD [4Fe-4S] cluster.
Melissa Y Y Stewart, Matthew J Bush, Jason C Crack, Mark J Buttner, Nick E Le Brun

J Biol Chem· July 2020

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Electron and Proton Transfers Modulate DNA Binding by the Transcription Regulator RsrR.
Jason C Crack, Patricia Amara, Anne Volbeda, Jean-Marie Mouesca, Roman Rohac

J Am Chem Soc· March 2020

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Mechanisms of iron- and O-sensing by the [4Fe-4S] cluster of the global iron regulator RirA.
Ma Teresa Pellicer Martinez, Jason C Crack, Melissa Yy Stewart, Justin M Bradley, Dimitri A Svistunenko

Elife· September 2019

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Mass Spectrometric Identification of [4Fe-4S](NO) Intermediates of Nitric Oxide Sensing by Regulatory Iron-Sulfur Cluster Proteins.
Jason C Crack, Nick E Le Brun

Chemistry· March 2019

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Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe-2S] Cluster Coordinated by Cys, Glu, and His Residues.
Anne Volbeda, Ma Teresa Pellicer Martinez, Jason C Crack, Patricia Amara, Océane Gigarel

J Am Chem Soc· February 2019

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Generation of S-substituted protein-bound [4Fe-4S] clusters using S-L-cysteine.
Jason C Crack, Melissa Y Y Stewart, Nick E Le Brun

Biol Methods Protoc· January 2019

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