Publications by authors named "Jason Comander"

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Higher Throughput Assays for Understanding the Pathogenicity of Variants of Unknown Significance in the RPE65 Gene.
Leila Azizzadeh Pormehr, Kannan Vrindavan Manian, Ha Eun Cho, T Michael Redmond, Jason Comander

Invest Ophthalmol Vis Sci· October 2025

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Giant Macular Hole in Enhanced S-Cone Syndrome.
Kirill Zaslavsky, Christopher F Barile, Jason I Comander

Ophthalmol Retina· August 2025

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Systematic empirical evaluation of individual base editing targets: Validating therapeutic targets in USH2A and comparison of methods.
Yuki Tachida, Kannan V Manian, Rossano Butcher, Jonathan M Levy, Nachiket Pendse, Jason Comander

Mol Ther· April 2025

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A comprehensive map of missense trafficking variants in rhodopsin and their response to pharmacologic correction.
Kannan V Manian, Connor H Ludwig, Yan Zhao, Nathan Abell, Xiaoping Yang, Jason Comander

bioRxiv· March 2025

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Higher throughput assays for understanding the pathogenicity of variants of unknown significance (VUS) in the RPE65 gene.
Leila Azizzadeh Pormehr, Kannan Vrindavan Manian, Ha Eun Cho, Jason Comander

bioRxiv· February 2025

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Phase 1/2 AAV5-hRKp.RPGR (Botaretigene Sparoparvovec) Gene Therapy: Safety and Efficacy in RPGR-Associated X-Linked Retinitis Pigmentosa.
Michel Michaelides, Cagri G Besirli, Yesa Yang, Thales A C DE Guimaraes, Sui Chien Wong, Jason I Comander

Am J Ophthalmol· November 2024

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Gene Editing for -Associated Retinal Degeneration.
Eric A Pierce, Tomas S Aleman, Kanishka T Jayasundera, Bright S Ashimatey, Keunpyo Kim, Jason I Comander

N Engl J Med· June 2024

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Structure-based network analysis predicts pathogenic variants in human proteins associated with inherited retinal disease.
Blake M Hauser, Yuyang Luo, Anusha Nathan, Ahmad Al-Moujahed, Demetrios G Vavvas, Jason Comander

NPJ Genom Med· May 2024

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Classification and Growth Rate of Chorioretinal Atrophy after Voretigene Neparvovec-Rzyl for RPE65-Mediated Retinal Degeneration.
Nikhil Bommakanti, Benjamin K Young, Robert A Sisk, Audina M Berrocal, Jacque L Duncan, Jason Comander

Ophthalmol Retina· January 2024

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Repair of Rhegmatogenous Retinal Detachment in Choroideremia Secondary to Posterior Extramacular Retinal Hole.
Jay C Wang, Cynthia X Qian, Jason I Comander

Ophthalmic Surg Lasers Imaging Retina· January 2024

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Natural history of retinitis pigmentosa based on genotype, vitamin A/E supplementation, and an electroretinogram biomarker.
Jason Comander, Carol Weigel DiFranco, Kit Sanderson, Emily Place, Matthew Maher

JCI Insight· August 2023

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Structure-based network analysis predicts mutations associated with inherited retinal disease.
Blake M Hauser, Yuyang Luo, Anusha Nathan, Gaurav D Gaiha, Demetrios Vavvas, Jason Comander

medRxiv· July 2023

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Perspectives of Rare Disease Experts on Newborn Genome Sequencing.
Nina B Gold, Sophia M Adelson, Nidhi Shah, Shardae Williams, Sarah L Bick, Jason Comander

JAMA Netw Open· May 2023

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Intravitreal Delivery of rAAV2tYF-CB-hRS1 Vector for Gene Augmentation Therapy in Patients with X-Linked Retinoschisis: 1-Year Clinical Results.
Mark Edward Pennesi, Paul Yang, David G Birch, Christina Y Weng, Anthony T Moore, Jason I Comander

Ophthalmol Retina· December 2022

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Adeno-Associated Virus Serotype 2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two-Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial.
Tomas S Aleman, Rachel M Huckfeldt, Leona W Serrano, Denise J Pearson, Grace K Vergilio, Jason Comander

Ophthalmology· October 2022

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Novel variants causing later-onset non-syndromic retinal dystrophy with macular chorioretinal atrophy.
Andrew J Catomeris, Brian G Ballios, Riccardo Sangermano, Naomi E Wagner, Jason I Comander

Ophthalmic Genet· June 2022

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Adeno-associated Viral Vectors in the Retina: Delivering Gene Therapy to the Right Destination.
Noam D Rudnick, Leo A Kim, Jason Comander

Int Ophthalmol Clin· April 2022

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Repair of Rhegmatogenous Retinal Detachment in Choroideremia Secondary to Posterior Extramacular Retinal Hole.
Jay C Wang, Cynthia X Qian, Jason I Comander

Ophthalmic Surg Lasers Imaging Retina· April 2022

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Beyond Sector Retinitis Pigmentosa: Expanding the Phenotype and Natural History of the Rhodopsin Gene Codon 106 Mutation (Gly-to-Arg) in Autosomal Dominant Retinitis Pigmentosa.
Brian G Ballios, Emily M Place, Luis Martinez-Velazquez, Eric A Pierce, Jason I Comander

Genes (Basel)· November 2021

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Biallelic -associated retinal dystrophies: Expanding the mutational and clinical spectrum.
Rachel M Huckfeldt, Florin Grigorian, Emily Place, Jason I Comander, Demetrios Vavvas

Mol Vis· May 2021

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Moving Towards PDE6A Gene Supplementation Therapy.
Kinga M Bujakowska, Jason Comander

JAMA Ophthalmol· December 2020

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Peripheral Leakage on Ultra-Widefield Fluorescein Angiography in Patients With Inherited Retinal Degeneration.
Elli A Park, Rachel M Huckfeldt, Jason I Comander, Lucia Sobrin

J Vitreoretin Dis· September 2020

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Copy-number variation contributes 9% of pathogenicity in the inherited retinal degenerations.
Erin Zampaglione, Benyam Kinde, Emily M Place, Daniel Navarro-Gomez, Matthew Maher, Jason Comander

Genet Med· June 2020

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Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses.
Jonathan M Levy, Wei-Hsi Yeh, Nachiket Pendse, Jessie R Davis, Erin Hennessey, Jason Comander

Nat Biomed Eng· January 2020

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Predictive value of genetic testing for inherited retinal diseases in patients with suspected atypical autoimmune retinopathy.
Lynn K Stanwyck, Emily M Place, Jason Comander, Rachel M Huckfeldt, Lucia Sobrin

Am J Ophthalmol Case Rep· September 2019

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