Publications by authors named "Jason D Brubaker"

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An ALK2 inhibitor, BLU-782, prevents heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva.
Alison J Davis, Natasja Brooijmans, Jason D Brubaker, Faith Stevison, Timothy P LaBranche

Sci Transl Med· May 2024

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Discovery of BLU-945, a Reversible, Potent, and Wild-Type-Sparing Next-Generation EGFR Mutant Inhibitor for Treatment-Resistant Non-Small-Cell Lung Cancer.
Meredith S Eno, Jason D Brubaker, John E Campbell, Chris De Savi, Timothy J Guzi

J Med Chem· July 2022

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Precision Targeted Therapy with BLU-667 for -Driven Cancers.
Vivek Subbiah, Justin F Gainor, Rami Rahal, Jason D Brubaker, Joseph L Kim

Cancer Discov· July 2018

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Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.
Graham F Smith, Michael D Altman, Brian Andresen, James Baker, Jason D Brubaker

Bioorg Med Chem Lett· June 2017

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Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.
Jongwon Lim, Michael D Altman, James Baker, Jason D Brubaker, Hongmin Chen

Bioorg Med Chem Lett· November 2015

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Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4.
Jongwon Lim, Michael D Altman, James Baker, Jason D Brubaker, Hongmin Chen

ACS Med Chem Lett· June 2015

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Reactions of oxetan-3-tert-butylsulfinimine for the preparation of substituted 3-aminooxetanes.
Philip J Hamzik, Jason D Brubaker

Org Lett· March 2010

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A robust platform for the synthesis of new tetracycline antibiotics.
Cuixiang Sun, Qiu Wang, Jason D Brubaker, Peter M Wright, Christian D Lerner

J Am Chem Soc· December 2008

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Preparation of the isomeric azaindoline family by intramolecular carbolithiation.
William F Bailey, Paresh D Salgaonkar, Jason D Brubaker, Vijayata Sharma

Org Lett· March 2008

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A practical, enantioselective synthetic route to a key precursor to the tetracycline antibiotics.
Jason D Brubaker, Andrew G Myers

Org Lett· August 2007

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A convergent enantioselective route to structurally diverse 6-deoxytetracycline antibiotics.
Mark G Charest, Christian D Lerner, Jason D Brubaker, Dionicio R Siegel, Andrew G Myers

Science· April 2005

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A general route to the synthesis of 1,5-methano- and 1,5-ethano- 2,3,4,5-tetrahydro-1H-3-benzazepines.
Christopher J O'Donnell, Robert A Singer, Jason D Brubaker, Jason D McKinley

J Org Chem· August 2004

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