Publications by authors named "Jason D Coombes"

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A human iPSC-based neural spheroid platform for modelling glioblastoma infiltration using high-content imaging.
Victoria S K Tsang, Federica Riccio, Aimee S Wilson, Hannah Nudds, Jason D Coombes

Sci Rep· December 2025

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Osteopontin Promotes Cholangiocyte Secretion of Chemokines to Support Macrophage Recruitment and Fibrosis in MASH.
Jason D Coombes, Paul P Manka, Marzena Swiderska-Syn, Danielle T Vannan, Antonio Riva

Liver Int· April 2025

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MASLD-Related HCC-Update on Pathogenesis and Current Treatment Options.
Catherine Leyh, Jason D Coombes, Hartmut H Schmidt, Ali Canbay, Paul P Manka

J Pers Med· March 2024

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Thyroid hormone receptor alpha modulates fibrogenesis in hepatic stellate cells.
Paul Manka, Jason D Coombes, Svenja Sydor, Marzena K Swiderska-Syn, Jan Best

Liver Int· January 2024

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A Potential Role for Bile Acid Signaling in Celiac Disease-Associated Fatty Liver.
Paul Manka, Svenja Sydor, Julia M Schänzer-Ocklenburg, Malte Brandenburg, Jan Best, Jason D Coombes

Metabolites· January 2022

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Anti-TNFα treatment in Crohn's disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status.
Paul Manka, Svenja Sydor, Nishikant Wase, Jan Best, Malte Brandenburg, Jason D Coombes

Liver Int· November 2021

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Targeting myosin 1c inhibits murine hepatic fibrogenesis.
Ehtesham Arif, Cindy Wang, Marzena K Swiderska-Syn, Ashish K Solanki, Bushra Rahman, Jason D Coombes

Am J Physiol Gastrointest Liver Physiol· June 2021

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A mode of cell adhesion and migration facilitated by CD44-dependent microtentacles.
Kayla J Wolf, Poojan Shukla, Kelsey Springer, Stacey Lee, Jason D Coombes

Proc Natl Acad Sci U S A· May 2020

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Low Free Triiodothyronine Is Associated with Advanced Fibrosis in Patients at High Risk for Nonalcoholic Steatohepatitis.
Paul Manka, Lars Bechmann, Jan Best, Svenja Sydor, Lee C Claridge, Jason D Coombes

Dig Dis Sci· August 2019

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Iron Enhances Hepatic Fibrogenesis and Activates Transforming Growth Factor-β Signaling in Murine Hepatic Stellate Cells.
Kosha J Mehta, Jason D Coombes, Marco Briones-Orta, Paul P Manka, Roger Williams

Am J Med Sci· February 2018

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Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter.
Marco Antonio Briones-Orta, S Eréndira Avendaño-Vázquez, Diana Ivette Aparicio-Bautista, Jason D Coombes, Georg F Weber

Data Brief· October 2017

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Osteopontin splice variants and polymorphisms in cancer progression and prognosis.
Marco Antonio Briones-Orta, S Eréndira Avendaño-Vázquez, Diana Ivette Aparicio-Bautista, Jason D Coombes, Georg F Weber

Biochim Biophys Acta Rev Cancer· August 2017

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Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis.
Jason D Coombes, Steve S Choi, Marzena Swiderska-Syn, Paul Manka, Danielle T Reid

Biochim Biophys Acta· January 2016

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Ras Transformation Overrides a Proliferation Defect Induced by Tpm3.1 Knockout.
Jason D Coombes, Galina Schevzov, Chin-Yi Kan, Carlotta Petti, Michelle F Maritz

Cell Mol Biol Lett· December 2015

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Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe.
Paul Manka, Lars P Bechmann, Jason D Coombes, Viktoria Thodou, Martin Schlattjan

Clin Gastroenterol Hepatol· October 2015

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Differential osteopontin functions: The role of osteopontin isoforms.
Jason D Coombes, Wing-Kin Syn

Hepatology· July 2015

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Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments.
Galina Schevzov, Anthony J Kee, Bin Wang, Vanessa B Sequeira, Jeff Hook, Jason D Coombes

Mol Biol Cell· July 2015

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Hedgehog-responsive progenitors: predictors of liver outcomes?
Jason D Coombes, Wing-Kin Syn

Hepatology· November 2012

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Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis.
Gopala K Rangan, Jason D Coombes

Nephrol Dial Transplant· August 2007

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Temporal relationship between renal cyst development, hypertension and cardiac hypertrophy in a new rat model of autosomal recessive polycystic kidney disease.
Jacqueline K Phillips, Deborah Hopwood, Rhonda A Loxley, Kamaljit Ghatora, Jason D Coombes

Kidney Blood Press Res· July 2007

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Sirolimus does not reduce receptor-mediated endocytosis of albumin in proximal tubule cells.
Ellein Mreich, Jason D Coombes, Gopala K Rangan

Transplantation· January 2007

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Effect of nephrotoxins on tubulointerstitial injury and NF-kappaB activation in Adriamycin nephropathy.
Gopala K Rangan, Yiping Wang, Yuet-Ching Tay, Jason D Coombes, David C H Harris

Ren Fail· December 2005

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Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy.
Jason D Coombes, Ellein Mreich, Christopher Liddle, Gopala K Rangan

Kidney Int· December 2005

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C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria.
Gopala K Rangan, Jeffrey W Pippin, Jason D Coombes, William G Couser

Kidney Int· February 2005

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