Publications by authors named "Jason D Heaney"

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Uncovering Phenotypic Expansion in AXIN2-Related Disorders through Precision Animal Modeling.
Nathalie M Aceves-Ewing, Denise G Lanza, Paul C Marcogliese, Di Lu, Chih-Wei Hsu, Jason D Heaney

medRxiv· March 2025

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A comprehensive atlas of AAV tropism in the mouse.
Christopher J Walkey, Kathy J Snow, Jote Bulcha, Aaron R Cox, Alexa E Martinez, Jason D Heaney

Mol Ther· March 2025

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ATRX silences Cartpt expression in osteoblastic cells during skeletal development.
Yi-Ting Chen, Ming-Ming Jiang, Carolina Leynes, Mary Adeyeye, Camilla F Majano, Jason D Heaney

J Clin Invest· January 2025

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Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity.
Matea Pavešković, Ruth B De-Paula, Shamsideen A Ojelade, Evelyne K Tantry, Mikhail Y Kochukov, Jason D Heaney

Hum Mol Genet· October 2024

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A Comprehensive Atlas of AAV Tropism in the Mouse.
Christopher J Walkey, Kathy J Snow, Jote Bulcha, Aaron R Cox, Alexa E Martinez, Jason D Heaney

bioRxiv· September 2024

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Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Hillary Elrick, Kevin A Peterson, Brandon J Willis, Denise G Lanza, Elif F Acar, Jason D Heaney

Sci Rep· September 2024

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Generation of a humanized mAce2 and a conditional hACE2 mouse models permissive to SARS-COV-2 infection.
I-Wen Song, Megan Washington, Carolina Leynes, Jason Hsu, Kempaiah Rayavara, Jason D Heaney

Mamm Genome· June 2024

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Machine learning in time-lapse imaging to differentiate embryos from young vs old mice†.
Liubin Yang, Carolina Leynes, Ashley Pawelka, Isabel Lorenzo, Andrew Chou, Jason D Heaney

Biol Reprod· June 2024

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Co-expression of prepulse inhibition and Schizophrenia genes in the mouse and human brain.
Lillian Garrett, Dietrich Trümbach, Donghyung Lee, Silvia Mandillo, Rodney Samaco, Jason D Heaney

Neurosci Appl· June 2024

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The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect.
Ronit Marom, I-Wen Song, Emily C Busse, Megan E Washington, Ava S Berrier, Jason D Heaney

J Clin Invest· June 2024

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An oocyte-specific Cas9-expressing mouse for germline CRISPR/Cas9-mediated genome editing.
Denise G Lanza, Jianqiang Mao, Isabel Lorenzo, Lan Liao, John R Seavitt, Jason D Heaney

Genesis· April 2024

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A GREB1-steroid receptor feedforward mechanism governs differential GREB1 action in endometrial function and endometriosis.
Sangappa B Chadchan, Pooja Popli, Zian Liao, Eryk Andreas, Michelle Dias, Jason D Heaney

Nat Commun· March 2024

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GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Nitish Rana, Giuseppe Privitera, Hannah C Kondolf, Katarzyna Bulek, Susana Lechuga, Jason D Heaney

Cell· February 2024

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Generation of a novel Stra8-driven Cre recombinase strain for use in pre-meiotic germ cells in mice†.
Avery A Ahmed, Ernesto Salas, Denise G Lanza, Jason D Heaney, Stephanie A Pangas

Biol Reprod· August 2023

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Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance.
Bridget M Stroup, Xiaohui Li, Sara Ho, Haonan Zhouyao, Yuqing Chen, Jason D Heaney

Dis Model Mech· August 2023

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A CRISPR/Cas9-engineered mouse carrying a conditional knockout allele for the early growth response-1 transcription factor.
Vineet K Maurya, Yan Ying, Denise G Lanza, Jason D Heaney, John P Lydon

Genesis· July 2023

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Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier.
Qin Huang, Albert T Chen, Ken Y Chan, Hikari Sorensen, Andrew J Barry, Jason D Heaney

PLoS Biol· July 2023

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Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice.
Manuela A Oestereicher, Janine M Wotton, Shinya Ayabe, Ghina Bou About, Tsz Kwan Cheng, Jason D Heaney

Mamm Genome· June 2023

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Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity.
Kevin A Peterson, Sam Khalouei, Nour Hanafi, Joshua A Wood, Denise G Lanza, Jason D Heaney

Commun Biol· June 2023

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In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector.
Reka Lorincz, Aluet Borrego Alvarez, Christopher J Walkey, Samir A Mendonça, Zhi Hong Lu, Jason D Heaney

Biomed Pharmacother· February 2023

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Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Justine M Chee, Louise Lanoue, Dave Clary, Kendall Higgins, Lynette Bower, Jason D Heaney

BMC Biol· February 2023

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Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes.
Kendall Higgins, Bret A Moore, Zorana Berberovic, Hibret A Adissu, Mohammad Eskandarian, Jason D Heaney

Sci Rep· December 2022

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Mendelian gene identification through mouse embryo viability screening.
Pilar Cacheiro, Carl Henrik Westerberg, Jesse Mager, Mary E Dickinson, Lauryl M J Nutter, Jason D Heaney

Genome Med· October 2022

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Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen.
Janine M Wotton, Emma Peterson, Ann M Flenniken, Rasneer S Bains, Surabi Veeraragavan, Jason D Heaney

Pain· June 2022

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Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy.
Nadine Spielmann, Gregor Miller, Tudor I Oprea, Chih-Wei Hsu, Gisela Fobo, Jason D Heaney

Nat Cardiovasc Res· May 2022

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