Publications by authors named "Jason Held"

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Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages.
Michael D Iglesia, Reyka G Jayasinghe, Siqi Chen, Nadezhda V Terekhanova, John M Herndon, Jason M Held

Nat Cancer· November 2024

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Tumour evolution and microenvironment interactions in 2D and 3D space.
Chia-Kuei Mo, Jingxian Liu, Siqi Chen, Erik Storrs, Andre Luiz N Targino da Costa, Jason M Held

Nature· October 2024

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The TRIM4 E3 ubiquitin ligase degrades TPL2 and is modulated by oncogenic KRAS.
Sapana Bansod, Paarth B Dodhiawala, Yutong Geng, Ashenafi Bulle, Peng Liu, Jason M Held

Cell Rep· September 2024

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Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models.
Zhanfang Guo, Jingqin Luo, R Jay Mashl, Jeremy Hoog, Piyush Maiti, Jason M Held

Cancer Res Commun· June 2024

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Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer.
Ashenafi Bulle, Peng Liu, Kuljeet Seehra, Sapana Bansod, Yali Chen, Jason M Held

Nat Commun· March 2024

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UNC-49 is a redox-sensitive GABA receptor that regulates the mitochondrial unfolded protein response cell nonautonomously.
Franziska Pohl, Allison L Germann, Jack Mao, Sydney Hou, Bayode Bakare, Jason M Held

Sci Adv· November 2023

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Epigenetic regulation during cancer transitions across 11 tumour types.
Nadezhda V Terekhanova, Alla Karpova, Wen-Wei Liang, Alexander Strzalkowski, Siqi Chen, Jason M Held

Nature· November 2023

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Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages.
Michael D Iglesia, Reyka G Jayasinghe, Siqi Chen, Nadezhda V Terekhanova, John M Herndon, Jason M Held

bioRxiv· November 2023

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Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin.
Meltem Barlin, Petra Erdmann-Gilmore, Jacqueline L Mudd, Qiang Zhang, Robert W Seymour, Jason M Held

Mol Cell Proteomics· January 2023

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Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102.
Caitlyn B Brashears, Bethany C Prudner, Richa Rathore, Katharine E Caldwell, Carina A Dehner, Jason M Held

Clin Cancer Res· August 2022

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Automating Assignment, Quantitation, and Biological Annotation of Redox Proteomics Datasets with ProteoSushi.
Sjoerd van der Post, Robert W Seymour, Arshag D Mooradian, Jason M Held

Methods Mol Biol· May 2022

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ProteoSushi: A Software Tool to Biologically Annotate and Quantify Modification-Specific, Peptide-Centric Proteomics Data Sets.
Robert W Seymour, Sjoerd van der Post, Arshag D Mooradian, Jason M Held

J Proteome Res· July 2021

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NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation.
Sjoerd van der Post, George M H Birchenough, Jason M Held

Cell Rep· April 2021

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Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.
Cuige Zhu, Sun-Joong Kim, Arshag Mooradian, Faliang Wang, Ziqian Li, Jason M Held

Cell Rep· February 2021

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A clickable probe for versatile characterization of S-nitrosothiols.
Jenna L Clements, Franziska Pohl, Pandi Muthupandi, Stephen C Rogers, Jack Mao, Jason M Held

Redox Biol· October 2020

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Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming.
Caitlyn B Brashears, Meltem Barlin, William R Ehrhardt, Richa Rathore, Matthew Schultze, Jason M Held

Cell Death Dis· August 2020

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Phospho-Ser-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer.
Cuige Zhu, Anna Rogers, Karama Asleh, Jennifer Won, Dongxia Gao, Jason M Held

Cell Rep· June 2020

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Redox Systems Biology: Harnessing the Sentinels of the Cysteine Redoxome.
Jason M Held

Antioxid Redox Signal· April 2020

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ProteoClade: A taxonomic toolkit for multi-species and metaproteomic analysis.
Arshag D Mooradian, Sjoerd van der Post, Kristen M Naegle, Jason M Held

PLoS Comput Biol· March 2020

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Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation.
Jessica B Behring, Sjoerd van der Post, Arshag D Mooradian, Matthew J Egan, Maxwell I Zimmerman, Jason M Held

Sci Signal· January 2020

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Regulated Phosphosignaling Associated with Breast Cancer Subtypes and Druggability.
Kuan-Lin Huang, Yige Wu, Tina Primeau, Yi-Ting Wang, Yuqian Gao, Jason Held

Mol Cell Proteomics· August 2019

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Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers.
Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly V Ruggles, Arshag D Mooradian, Jason M Held

Cancer Res· May 2018

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Using ProteomeScout: A Resource of Post-Translational Modifications, Their Experiments, and the Proteins That They Annotate.
Arshag D Mooradian, Jason M Held, Kristen M Naegle

Curr Protoc Bioinformatics· September 2017

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Breast tumors educate the proteome of stromal tissue in an individualized but coordinated manner.
Xuya Wang, Arshag D Mooradian, Petra Erdmann-Gilmore, Qiang Zhang, Rosa Viner, Jason M Held

Sci Signal· August 2017

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Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry.
Ben C Collins, Christie L Hunter, Yansheng Liu, Birgit Schilling, George Rosenberger, Jason M Held

Nat Commun· August 2017

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