Publications by authors named "Jason Heth"

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Adaptive nuclear GTP synthesis promotes glioblastoma treatment resistance and is a targetable vulnerability in patients.
Andrew J Scott, Ningning Liang, Wajd N Al-Holou, Jie Xu, Alexandra O'Brien, Jason A Heth

medRxiv· November 2025

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A Phase 2 Study of Multiparametric Magnetic Resonance Imaging-Guided High-Dose Response-Adaptive Radiation Therapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma: Results From an Interim Analysis.
Michelle M Kim, Madhava P Aryal, Krithika Suresh, Benjamin S Rosen, Hemant Parmar, Jason Heth

Int J Radiat Oncol Biol Phys· July 2025

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Three-dimensional topological defects and quasi-long-range order in biological liquid crystals.
Anna E Argento, Maria L Varela, Gurveer Singh, Daiana P Visnuk, Binyamin Jacobovitz, Jason A Heth

bioRxiv· May 2025

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PCO25-212: Examining Molecular Features of Rare Brain Metastases Patient-Derived Xenograft Models.
Noreen F Khan, Derek Nancarrow, Peter Ulintz, Tusharika Rastogi, Habib Serhan, Jason Heth

J Natl Compr Canc Netw· March 2025

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Targeting fatty acid synthase in preclinical models of TNBC brain metastases synergizes with SN-38 and impairs invasion.
Habib A Serhan, Liwei Bao, Xu Cheng, Zhaoping Qin, Chia-Jen Liu, Jason A Heth

NPJ Breast Cancer· June 2024

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Milestones for neurosurgery sub-interns: a novel evaluation tool to quantitatively differentiate residency applicants.
Stephen G Bowden, Hao Tan, Michael G Rothbaum, Steven H Cook, Simon Hanft, Jason Heth

J Neurosurg· December 2023

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Metabolomic Profiles of Human Glioma Inform Patient Survival.
Andrew J Scott, Luis O Correa, Donna M Edwards, Yilun Sun, Visweswaran Ravikumar, Jason Heth

Antioxid Redox Signal· November 2023

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Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Yoshie Umemura, Daniel Orringer, Larry Junck, Maria L Varela, Molly E J West, Jason Heth

Lancet Oncol· September 2023

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Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response Assessment.
Aki Morikawa, Jinju Li, Peter Ulintz, Xu Cheng, Athena Apfel, Jason Heth

Cancer Res Commun· June 2023

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102 AI-Based Molecular Classification of Diffuse Gliomas using Rapid, Label-Free Optical Imaging.
Todd Charles Hollon, John G Golfinos, Daniel A Orringer, Mitchel Berger, Shawn L Hervey-Jumper, Jason Heth

Neurosurgery· April 2023

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Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging.
Todd Hollon, Cheng Jiang, Asadur Chowdury, Mustafa Nasir-Moin, Akhil Kondepudi, Jason Heth

Nat Med· April 2023

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Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma.
Wajd N Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Jason A Heth

Neoplasia· February 2023

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IMPACT the Brain: A Team-Based Approach to Management of Metastatic Breast Cancer With CNS Metastases.
Nicole M Grogan Fleege, Donna Pierce-Gjeldum, Leigh K Swartz, Kait Verbal, Sofia Merajver, Jason Heth

JCO Oncol Pract· January 2023

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Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Jason A Heth

JAMA Oncol· January 2023

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Correlation between brain tissue oxygen tension and regional cerebral oximetry in uninjured human brain under conditions of changing ventilation strategy.
Paul Picton, Phillip E Vlisides, Magnus K Teig, Jason A Heth, Daniel Orringer

J Clin Monit Comput· August 2022

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Rapid Automated Analysis of Skull Base Tumor Specimens Using Intraoperative Optical Imaging and Artificial Intelligence.
Cheng Jiang, Abhishek Bhattacharya, Joseph R Linzey, Rushikesh S Joshi, Sung Jik Cha, Jason A Heth

Neurosurgery· June 2022

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Commentary: An Examination of Standardized Letters of Recommendation Rating Scales Among Neurosurgical Residency Candidates During the 2020 to 2021 Application Cycle.
Jason Heth, Stacey Quintero Wolfe

Neurosurgery· November 2021

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G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy.
Mahmoud S Alghamri, Brandon L McClellan, Ruthvik P Avvari, Rohit Thalla, Stephen Carney, Jason Heth

Sci Adv· October 2021

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Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan Sweha, Jason Heth

Sci Transl Med· October 2021

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A customized 3D implant to target laser interstitial thermal therapy ablation of a posterior fossa mass.
Julia Kozlowski, Kyle VanKoevering, Jason A Heth

J Clin Neurosci· August 2021

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A Phase 2 Study of Dose-intensified Chemoradiation Using Biologically Based Target Volume Definition in Patients With Newly Diagnosed Glioblastoma.
Michelle M Kim, Yilun Sun, Madhava P Aryal, Hemant A Parmar, Morand Piert, Jason Heth

Int J Radiat Oncol Biol Phys· July 2021

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Introduction to special issue dedicated to the 35th anniversary of the joint section on tumors.
Isabelle M Germano, Jason Heth, Pamela S Jones, Manish K Aghi

J Neurooncol· February 2021

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Rapid, label-free detection of diffuse glioma recurrence using intraoperative stimulated Raman histology and deep neural networks.
Todd C Hollon, Balaji Pandian, Esteban Urias, Akshay V Save, Arjun R Adapa, Jason A Heth

Neuro Oncol· January 2021

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In Reply: Thirty-Day Hospital Readmission and Surgical Complication Rates for Shunting in Normal Pressure Hydrocephalus: A Large National Database Analysis.
Jason A Heth

Neurosurgery· November 2020

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Utilization of a Resuscitative Care Unit for Initial Triage, Management, and Disposition of Minor Intracranial Hemorrhage.
Jacob R Joseph, Nathan L Haas, John R Joseph, Jason Heth, Nicholas J Szerlip

Crit Care Explor· April 2020

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