Publications by authors named "Jason Karpac"

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NF-κB restrains nutrient-dependent transcription programs through chromatin modulation in .
Xiangshuo Kong, Conghui Li, Jason Karpac

bioRxiv· October 2025

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Diacylglycerol metabolism drives host-pathogen responses during enteric infection in .
Xiaotong Li, Mohamed Mlih, Jason Karpac

bioRxiv· September 2025

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Inter-organ communication in Drosophila: Lipoproteins, adipokines, and immune-metabolic coordination.
Akhila Rajan, Jason Karpac

Curr Opin Cell Biol· June 2025

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Membrane therapy using DHA suppresses epidermal growth factor receptor signaling by disrupting nanocluster formation.
Natividad R Fuentes, Mohamed Mlih, Xiaoli Wang, Gabriella Webster, Sergio Cortes-Acosta, Jason Karpac

J Lipid Res· July 2024

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A distinct Acyl-CoA binding protein (ACBP6) shapes tissue plasticity during nutrient adaptation in Drosophila.
Xiaotong Li, Jason Karpac

Nat Commun· November 2023

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Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin.
Alfredo Erazo-Oliveras, Mónica Muñoz-Vega, Mohamed Mlih, Venkataramana Thiriveedi, Michael L Salinas, Jason Karpac

Nat Commun· July 2023

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Adaptive physiology drives ageing plasticity in locusts.
Xiaotong Li, Jason Karpac

Nat Ecol Evol· June 2023

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Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis.
Chi G Weindel, Eduardo L Martinez, Xiao Zhao, Cory J Mabry, Samantha L Bell, Jason Karpac

Cell· August 2022

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Integrin-ECM interactions and membrane-associated Catalase cooperate to promote resilience of the Drosophila intestinal epithelium.
Mohamed Mlih, Jason Karpac

PLoS Biol· May 2022

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Glutamate metabolism directs energetic trade-offs to shape host-pathogen susceptibility in Drosophila.
Xiao Zhao, Jason Karpac

Cell Metab· December 2021

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The Drosophila midgut and the systemic coordination of lipid-dependent energy homeostasis.
Xiao Zhao, Jason Karpac

Curr Opin Insect Sci· October 2020

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Diet-MEF2 interactions shape lipid droplet diversification in muscle to influence Drosophila lifespan.
Xiao Zhao, Xiaotong Li, Xiangyu Shi, Jason Karpac

Aging Cell· July 2020

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Dietary Adaptation of Microbiota in Drosophila Requires NF-κB-Dependent Control of the Translational Regulator 4E-BP.
Crissie Vandehoef, Maral Molaei, Jason Karpac

Cell Rep· June 2020

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NF-κB Shapes Metabolic Adaptation by Attenuating Foxo-Mediated Lipolysis in Drosophila.
Maral Molaei, Crissie Vandehoef, Jason Karpac

Dev Cell· June 2019

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Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition.
Natividad R Fuentes, Mohamed Mlih, Rola Barhoumi, Yang-Yi Fan, Paul Hardin, Jason Karpac

Cancer Res· July 2018

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A virus-acquired host cytokine controls systemic aging by antagonizing apoptosis.
Mohamed Mlih, Mobina Khericha, Christine Birdwell, A Phillip West, Jason Karpac

PLoS Biol· July 2018

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Muscle Directs Diurnal Energy Homeostasis through a Myokine-Dependent Hormone Module in Drosophila.
Xiao Zhao, Jason Karpac

Curr Biol· July 2017

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Intestinal IRE1 Is Required for Increased Triglyceride Metabolism and Longer Lifespan under Dietary Restriction.
Nuno Miguel Luis, Lifen Wang, Mauricio Ortega, Hansong Deng, Subhash D Katewa, Jason Karpac

Cell Rep· October 2016

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Promoting longevity by maintaining metabolic and proliferative homeostasis.
Lifen Wang, Jason Karpac, Heinrich Jasper

J Exp Biol· January 2014

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PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan.
Linlin Guo, Jason Karpac, Susan L Tran, Heinrich Jasper

Cell· January 2014

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Misregulation of an adaptive metabolic response contributes to the age-related disruption of lipid homeostasis in Drosophila.
Jason Karpac, Benoit Biteau, Heinrich Jasper

Cell Rep· September 2013

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Aging: seeking mitonuclear balance.
Jason Karpac, Heinrich Jasper

Cell· July 2013

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Notch-mediated suppression of TSC2 expression regulates cell differentiation in the Drosophila intestinal stem cell lineage.
Subir Kapuria, Jason Karpac, Benoit Biteau, DaeSung Hwangbo, Heinrich Jasper

PLoS Genet· May 2013

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Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage.
Jason Karpac, Andrew Younger, Heinrich Jasper

Dev Cell· June 2011

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Metabolic homeostasis: HDACs take center stage.
Jason Karpac, Heinrich Jasper

Cell· May 2011

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