Publications by authors named "Jason Kwon"

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Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis.
Jeffrey C Hsiao, Douglas M Warui, Jason J Kwon, Margaret B Dreishpoon, Nolan R Bick

Nat Commun· December 2025

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A Hydrogel Culture System Regulates Human Adipocyte Function.
Jason Junhyoung Kwon, Jie Li, Joshua Yu-Chung Liu, Christopher Patsalis, Peizi Wu

Int J Mol Sci· November 2025

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Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes.
Justin Hwang, Pornlada Likasitwatanakul, Sachin Kumar Deshmukh, Sharon Wu, Jason J Kwon

Clin Cancer Res· March 2025

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A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria.
Alexander M Telenson, Ryan R Hsieh, Gabrielle J Cowen, Eoin P Sode, Jason M Kwon

FASEB J· March 2025

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Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.
Jason J Kwon, Julien Dilly, Shengwu Liu, Eejung Kim, Yuemin Bian

bioRxiv· October 2024

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On knowing a gene: A distributional hypothesis of gene function.
Jason J Kwon, Joshua Pan, Guadalupe Gonzalez, William C Hahn, Marinka Zitnik

Cell Syst· June 2024

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The extracellular matrix differentially directs myoblast motility and differentiation in distinct forms of muscular dystrophy: Dystrophic matrices alter myoblast motility.
Ashlee M Long, Jason M Kwon, GaHyun Lee, Nina L Reiser, Lauren A Vaught

Matrix Biol· May 2024

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The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix.
Joseph G O'Brien, Alexander B Willis, Ashlee M Long, Jason Kwon, GaHyun Lee

JCI Insight· January 2024

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The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix.
Joseph G O'Brien, Alexander B Willis, Ashlee M Long, Jason Kwon, GaHyun Lee

bioRxiv· June 2023

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Target-driven machine learning-enabled virtual screening (TAME-VS) platform for early-stage hit identification.
Yuemin Bian, Jason J Kwon, Cong Liu, Enrico Margiotta, Mrinal Shekhar

Front Mol Biosci· March 2023

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VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system.
Jonathan So, Nathaniel W Mabe, Bernhard Englinger, Kin-Hoe Chow, Sydney M Moyer, Jason J Kwon

JCI Insight· October 2022

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Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.
Jason J Kwon, Behnoush Hajian, Yuemin Bian, Lucy C Young, Alvaro J Amor

Nature· September 2022

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Systematic profiling of conditional degron tag technologies for target validation studies.
Daniel P Bondeson, Zachary Mullin-Bernstein, Sydney Oliver, Thomas A Skipper, Thomas C Atack, Jason Kwon

Nat Commun· September 2022

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CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies.
Justin H Hwang, Rand Arafeh, Ji-Heui Seo, Sylvan C Baca, Megan Ludwig, Jason Kwon

Elife· May 2022

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Sparse dictionary learning recovers pleiotropy from human cell fitness screens.
Joshua Pan, Jason J Kwon, Jessica A Talamas, Ashir A Borah, Francisca Vazquez

Cell Syst· April 2022

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Loss of miR-29a/b1 promotes inflammation and fibrosis in acute pancreatitis.
Shatovisha Dey, Lata M Udari, Primavera RiveraHernandez, Jason J Kwon, Brandon Willis

JCI Insight· October 2021

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A Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective.
Jason J Kwon, William C Hahn

Mol Cell Biol· March 2021

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miR-29a Is Repressed by MYC in Pancreatic Cancer and Its Restoration Drives Tumor-Suppressive Effects via Downregulation of LOXL2.
Shatovisha Dey, Jason J Kwon, Sheng Liu, Gabriel A Hodge, Solaema Taleb

Mol Cancer Res· February 2020

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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.
Rita Sulahian, Jason J Kwon, Katherine H Walsh, Emma Pailler, Timothy L Bosse

Cell Rep· October 2019

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A Systematic Review of miR-29 in Cancer.
Jason J Kwon, Tricia D Factora, Shatovisha Dey, Janaiah Kota

Mol Ther Oncolytics· March 2019

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Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice.
Kayla A Quirin, Jason J Kwon, Arafat Alioufi, Tricia Factora, Constance J Temm

Mol Ther Methods Clin Dev· March 2018

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Pancreatic cancer: Stroma and its current and emerging targeted therapies.
Janaiah Kota, Julie Hancock, Jason Kwon, Murray Korc

Cancer Lett· April 2017

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Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential.
Jason J Kwon, Jeffrey A Willy, Kayla A Quirin, Ronald C Wek, Murray Korc

Oncotarget· November 2016

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Pathophysiological role of microRNA-29 in pancreatic cancer stroma.
Jason J Kwon, Sarah C Nabinger, Zachary Vega, Smiti Snigdha Sahu, Ravi K Alluri

Sci Rep· June 2015

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