Publications by authors named "Jason Lohmueller"

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Modeling recent human evolution in mice by expression of a selected EDAR variant.
Yana G Kamberov, Sijia Wang, Jingze Tan, Pascale Gerbault, Abigail Wark, Longzhi Tan, Yajun Yang, Shilin Li, Kun Tang, Hua Chen

Cell· February 2013

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Small-molecule control of CAR T cells.
Eric L Adams, Andrew C McGovern, Victor So, Sneha Srinivasan, Alexander Deiters, Jason Lohmueller

Nat Rev Chem· December 2025

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Conditional Control of Benzylguanine Reaction with the Self-Labeling SNAP-tag Protein.
Steven E Caldwell, Isabella R Demyan, Gianna N Falcone, Avani Parikh, Jason Lohmueller

Bioconjug Chem· March 2025

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Preventative Cancer Vaccine-Elicited Human Anti-MUC1 Antibodies Have Multiple Effector Functions.
Michelle L McKeague, Jason Lohmueller, Matthew T Dracz, Najla Saadallah, Eric D Ricci

Antibodies (Basel)· October 2024

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CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays.
Youngbin Cho, Matthew S Laird, Teddi Bishop, Ruxuan Li, Dorota E Jazwinska, Jason Lohmueller

APL Bioeng· September 2024

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CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under control of antigen sensing in microwell arrays.
Youngbin Cho, Matthew Laird, Teddi Bishop, Ruxuan Li, Elisa Ruffo, Jason Lohmueller

bioRxiv· March 2024

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Conditional Control of Universal CAR T Cells by Cleavable OFF-Switch Adaptors.
Michael Kvorjak, Elisa Ruffo, Yaniv Tivon, Victor So, Avani Parikh, Jason Lohmueller

ACS Synth Biol· October 2023

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Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting.
Elisa Ruffo, Adam A Butchy, Yaniv Tivon, Victor So, Michael Kvorjak, Jason Lohmueller

Nat Commun· May 2023

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Conditional control of universal CAR T cells by cleavable OFF-switch adaptors.
Michael Kvorjak, Elisa Ruffo, Yaniv Tivon, Victor So, Avani B Parikh, Jason Lohmueller

bioRxiv· May 2023

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Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors.
Konstantinos Lontos, Yiyang Wang, Supriya K Joshi, Andrew T Frisch, McLane J Watson, Jason Lohmueller

J Immunother Cancer· March 2023

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Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology.
Konstantinos Lontos, Yiyang Wang, Mason Colbert, Alok Kumar, Supriya Joshi, Jason Lohmueller

Oncoimmunology· October 2022

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The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse.
Shunsuke Kataoka, Priyanka Manandhar, Judong Lee, Creg J Workman, Hridesh Banerjee, Jason Lohmueller

Sci Signal· June 2021

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Editorial.
Jason Lohmueller, Sandra Cascio

Cell Immunol· September 2019

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Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer.
Sandra Cascio, Jacque L Faylo, Joshua C Sciurba, Jia Xue, Sarangarajan Ranganathan, Jason J Lohmueller

Oncotarget· December 2017

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Current modalities in cancer immunotherapy: Immunomodulatory antibodies, CARs and vaccines.
Jason Lohmueller, Olivera J Finn

Pharmacol Ther· October 2017

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mSA2 affinity-enhanced biotin-binding CAR T cells for universal tumor targeting.
Jason J Lohmueller, James D Ham, Michael Kvorjak, Olivera J Finn

Oncoimmunology· October 2017

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Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential.
Jason J Lohmueller, Shuji Sato, Lana Popova, Isabel M Chu, Meghan A Tucker

Sci Rep· August 2016

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Synthetic biology in mammalian cells: next generation research tools and therapeutics.
Florian Lienert, Jason J Lohmueller, Abhishek Garg, Pamela A Silver

Nat Rev Mol Cell Biol· February 2014

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Protein scaffold-activated protein trans-splicing in mammalian cells.
Daniel F Selgrade, Jason J Lohmueller, Florian Lienert, Pamela A Silver

J Am Chem Soc· May 2013

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Engineering synthetic TAL effectors with orthogonal target sites.
Abhishek Garg, Jason J Lohmueller, Pamela A Silver, Thomas Z Armel

Nucleic Acids Res· August 2012

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A tunable zinc finger-based framework for Boolean logic computation in mammalian cells.
Jason J Lohmueller, Thomas Z Armel, Pamela A Silver

Nucleic Acids Res· June 2012

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MicroRNA circuits for transcriptional logic.
Madeleine Leisner, Leonidas Bleris, Jason Lohmueller, Zhen Xie, Yaakov Benenson

Methods Mol Biol· March 2012

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Rationally designed logic integration of regulatory signals in mammalian cells.
Madeleine Leisner, Leonidas Bleris, Jason Lohmueller, Zhen Xie, Yaakov Benenson

Nat Nanotechnol· September 2010

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Genome-wide detection and characterization of positive selection in human populations.
Pardis C Sabeti, Patrick Varilly, Ben Fry, Jason Lohmueller, Elizabeth Hostetter

Nature· October 2007

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