Overall, the discussions show a high level of interest and engagement, with many posts citing supporting research and emphasizing the significance of the findings, such as links between the EDAR variant and human adaptations. The tone is analytical and critical, with some posts explicitly refuting pseudoscience, highlighting how the article impacts scientific discourse.
AgreementNeither agree nor disagree
The discussions largely reject pseudoscientific claims and endorse the article's findings, showing a neutral to slightly positive stance.
InterestHigh interest
There is high interest, as many posts reference detailed studies, genetic pathways, and scientific refutations.
EngagementHigh engagement
Posts demonstrate deep engagement through citations of related works, discussions on genetic mechanisms, and critiques of alternative theories.
ImpactModerate impact
The discussions suggest the article influences ongoing debates in genetics and evolution, though mostly within academic or scientifically inclined audiences.
Abstract in brief
The study models a human genetic variant, EDAR370A, in mice to understand its role in human evolution, suggesting it originated in central China about 30,000 years ago.
Mice with the EDAR370A variant show increased hair thickness, similar to humans, and also exhibit changes in mammary and sweat gland development, indicating multiple biological effects.
The research links the EDAR370A variant to a higher number of active sweat glands in Han Chinese people, providing insights into how this mutation may have helped in human adaptation.]
EDARV370A is super interesting because it increases the activity of the NF-kB pathway. This is the opposite of what is happening in an extremely high omega-3 rich diet.
17/25
https://t.co/MrI3AYR8Jz
Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant
https://t.co/pPWXPf1p6j &
Identifying Recent Adaptations in Large-Scale Genomic Data https://t.co/EWqKsSpXhP refute the pseudoscientific nonsense touted in The ATP Hypothesis https://t.co/TKxU6Wub24
Jun 13, 2021 · 1 like · 2,573 followersView post →
JK
James V. Kohl
@microRNApro · X
See: Nutrient-dependent Pheromone-Controlled Ecological Adaptations https://t.co/5VkgY01ZXQ 4/18/18 I cited: Kamberov et al., (2013) Modeling recent human evolution in mice by expression of a selected EDAR variant." and Grossman et al. (2013) Identifying recent adaptations...
Aug 30, 2021 · 1 like · 2,573 followersView post →
JK
James V. Kohl
@microRNApro · X
"Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant" https://t.co/pPWXPf1p6j links fixation of one amino acid substitution: EDAR V370A from the mouse to human model of microRNA-mediated #naturally_attenuated #viral_latency via https://t.co/zhVN9QMWvY
Dec 15, 2021 · 1 like · 2,573 followersView post →
Jul 2, 2025 · 1 like · 1 share · 796 followersView post →
JK
James V. Kohl
@microRNApro · X
@caoresco claims to be "...interested in epigenetic control of mammary gland development and breast cancer." There's a model for that. Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant (2013) https://t.co/pPWXPf1p6j /1
This study investigates whether variations in human nose shape are adaptations to climate, exploring genetic differences and environmental correlations, indicating climate's influence on nasal morphology.
This study models the human EDAR370A gene variant in mice to understand its role in human evolution, revealing its impact on hair, gland development, and potential adaptive benefits in ancient populations.
Jul 2, 2025 · 1 like · 1 share · 796 followersView post →
JK
James V. Kohl
@microRNApro · X
https://t.co/ibGmzqnkhS "As cited in Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13, See: Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant 2/14/13
"Modeling recent human evolution in mice by expression of a selected EDAR variant" https://t.co/q74QezJSso 2/14/13 links claims that theorists know nothing about energy-dependent miRNA-mediated #RNAi, which links angstroms to ecosystems across kingdoms.
See:
See: "Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant" [rs3827760] https://t.co/pPWXPf1p6j 2/14/13
It was reported in https://t.co/C1AXeB3wDr 6/14/13 -- a refutation of neo-Darwiinian pseudoscientific nonsense and Big Bang Cosmology.
"Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant" https://t.co/pPWXPf1p6j presciently linked one SNP, EDAR 370A, from prevention of alopecia to biophysically contained viral endemicity across kingdoms via https://t.co/TswDCTlOJ0
EDARV370A is super interesting because it increases the activity of the NF-kB pathway. This is the opposite of what is happening in an extremely high omega-3 rich diet.
17/25
https://t.co/MrI3AYR8Jz
"Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant" https://t.co/pPWXPf1p6j links fixation of one amino acid substitution: EDAR V370A from the mouse to human model of microRNA-mediated #naturally_attenuated #viral_latency via https://t.co/zhVN9QMWvY
Dec 15, 2021 · 1 like · 2,573 followersView post →
JK
James V. Kohl
@microRNApro · X
See: Nutrient-dependent Pheromone-Controlled Ecological Adaptations https://t.co/5VkgY01ZXQ 4/18/18 I cited: Kamberov et al., (2013) Modeling recent human evolution in mice by expression of a selected EDAR variant." and Grossman et al. (2013) Identifying recent adaptations...
Aug 30, 2021 · 1 like · 2,573 followersView post →
JK
James V. Kohl
@microRNApro · X
Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant
https://t.co/pPWXPf1p6j &
Identifying Recent Adaptations in Large-Scale Genomic Data https://t.co/EWqKsSpXhP refute the pseudoscientific nonsense touted in The ATP Hypothesis https://t.co/TKxU6Wub24
Jun 13, 2021 · 1 like · 2,573 followersView post →
JK
James V. Kohl
@microRNApro · X
See: https://t.co/pPWXPf1p6j Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant and https://t.co/6xKXugvnV2 11/28/12 "The findings confirm...that the majority of variants... were picked up during the past 5,000–10,000 years."
Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems https://t.co/5VkgY01ZXQ 4/18/18 cites: Kamberov YG et al., (2013) "Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell 152: 691-702." /4
@caoresco claims to be "...interested in epigenetic control of mammary gland development and breast cancer." There's a model for that. Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant (2013) https://t.co/pPWXPf1p6j /1
RT @XiXiDu: Modeling recent human evolution in mice by expression of a selected EDAR variant https://t.co/OiUbVm5kBK
Jun 29, 2020 · 2 shares · 544 followersView post →
JK
James V. Kohl
@microRNApro · X
ICYMI: Kamberov et al., (2013) Modeling recent human evolution in mice by expression of a selected EDAR variant and Grossman et al., (2013) Identifying recent adaptations... are the last two cited works from https://t.co/qTsFIDk7Vk, which refuted all your ridiculous theories.
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JK
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