Publications by authors named "Jason M Fye"

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Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis.
Joan Manils, Diana Gómez, Mercè Salla-Martret, Heinz Fischer, Jason M Fye

Oncotarget· September 2015

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Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Jessica L Grieves, Jason M Fye, Scott Harvey, Jason M Grayson, Thomas Hollis

Proc Natl Acad Sci U S A· April 2015

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The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers.
Jason M Fye, Stephanie R Coffin, Clinton D Orebaugh, Thomas Hollis, Fred W Perrino

J Biol Chem· April 2014

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The TREX1 C-terminal region controls cellular localization through ubiquitination.
Clinton D Orebaugh, Jason M Fye, Scott Harvey, Thomas Hollis, John C Wilkinson

J Biol Chem· October 2013

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The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
Clinton D Orebaugh, Jason M Fye, Scott Harvey, Thomas Hollis, Fred W Perrino

J Biol Chem· November 2011

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Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.
Jason M Fye, Clinton D Orebaugh, Stephanie R Coffin, Thomas Hollis, Fred W Perrino

J Biol Chem· September 2011

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