Publications by authors named "Jason Mezey"

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SeqTrial: Utility Preserving Sequential Clinical Trial Data Generator.
Trisha Das, Afrah Shafquat, Mandis Beigi, Jacob Aptekar, Jason Mezey

AMIA Annu Symp Proc· May 2025

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Predicted deleterious variants in the human genome relevant to gene therapy with adeno-associated virus vectors.
Mahboubeh R Rostami, Philip L Leopold, Jenifer M Vasquez, Miguel de Mulder Rougvie, Alya Al Shakaki, Jason G Mezey

Mol Ther Methods Clin Dev· December 2023

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Serial Sampling of the Small Airway Epithelium to Identify Persistent Smoking-dysregulated Genes.
Yael Strulovici-Barel, Mahboubeh R Rostami, Robert J Kaner, Jason G Mezey, Ronald G Crystal

Am J Respir Crit Care Med· October 2023

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Simulants: Synthetic Clinical Trial Data via Subject-Level Privacy-Preserving Synthesis.
Mandis Beigi, Afrah Shafquat, Jason Mezey, Jacob Aptekar

AMIA Annu Symp Proc· May 2023

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Simple Linear Cancer Risk Prediction Models With Novel Features Outperform Complex Approaches.
Scott Kulm, Lior Kofman, Jason Mezey, Olivier Elemento

JCO Clin Cancer Inform· February 2022

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The QChip1 knowledgebase and microarray for precision medicine in Qatar.
Juan L Rodriguez-Flores, Radja Messai-Badji, Amal Robay, Ramzi Temanni, Najeeb Syed, Jason G Mezey

NPJ Genom Med· January 2022

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Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease.
Sheila K Pierson, Sushila Shenoy, Ana B Oromendia, Alexander M Gorzewski, Ruth-Anne Langan Pai, Jason Mezey

Blood Adv· September 2021

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Smoking shifts human small airway epithelium club cells toward a lesser differentiated population.
Mahboubeh R Rostami, Michelle G LeBlanc, Yael Strulovici-Barel, Wulin Zuo, Jason G Mezey

NPJ Genom Med· September 2021

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Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing .
Dolan Sondhi, Stephen M Kaminsky, Neil R Hackett, Odelya E Pagovich, Jonathan B Rosenberg, Jason G Mezey

Sci Transl Med· December 2020

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Reply to Sharma and Zeki: Does Vaping Increase Susceptibility to COVID-19?
Haijun Zhang, Mahboubeh R Rostamim, Philip L Leopold, Jason G Mezey, Sarah L O'Beirne

Am J Respir Crit Care Med· October 2020

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Dysregulation of club cell biology in idiopathic pulmonary fibrosis.
Wu-Lin Zuo, Mahboubeh R Rostami, Michelle LeBlanc, Robert J Kaner, Sarah L O'Beirne, Jason G Mezey

PLoS One· October 2020

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Expression of the SARS-CoV-2 Receptor in the Human Airway Epithelium.
Haijun Zhang, Mahboubeh R Rostami, Philip L Leopold, Jason G Mezey, Sarah L O'Beirne

Am J Respir Crit Care Med· July 2020

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Cell-specific expression of lung disease risk-related genes in the human small airway epithelium.
Wu-Lin Zuo, Mahboubeh R Rostami, Shushila A Shenoy, Michelle G LeBlanc, Jacqueline Salit, Jason G Mezey

Respir Res· July 2020

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Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues.
Andrew R Marderstein, Manik Uppal, Akanksha Verma, Bhavneet Bhinder, Zakieh Tayyebi, Jason Mezey

Nat Commun· May 2020

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Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes.
Afrah Shafquat, Ronald G Crystal, Jason G Mezey

BMC Bioinformatics· May 2020

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Point of Care Exome Sequencing Reveals Allelic and Phenotypic Heterogeneity Underlying Mendelian disease in Qatar.
Khalid A Fakhro, Amal Robay, Juan L Rodrigues-Flores, Jason G Mezey, Alya A Al-Shakaki

Hum Mol Genet· December 2019

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Role of KRAS in regulating normal human airway basal cell differentiation.
Fumihiro Ogawa, Matthew S Walters, Afrah Shafquat, Sarah L O'Beirne, Robert J Kaner, Jason G Mezey

Respir Res· August 2019

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Exaggerated BMP4 signalling alters human airway basal progenitor cell differentiation to cigarette smoking-related phenotypes.
Wu-Lin Zuo, Jing Yang, Yael Strulovici-Barel, Jacqueline Salit, Mahboubeh Rostami, Jason G Mezey

Eur Respir J· May 2019

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Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population.
Sarah L O'Beirne, Jacqueline Salit, Juan L Rodriguez-Flores, Michelle R Staudt, Charbel Abi Khalil, Jason G Mezey

PLoS One· February 2019

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Whole-methylome analysis of circulating monocytes in acute diabetic Charcot foot reveals differentially methylated genes involved in the formation of osteoclasts.
Jennifer Pasquier, Mark Spurgeon, Martina Bradic, Binitha Thomas, Amal Robay, Jason Mezey

Epigenomics· February 2019

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Ontogeny and Biology of Human Small Airway Epithelial Club Cells.
Wu-Lin Zuo, Sushila A Shenoy, Sheng Li, Sarah L O'Beirne, Yael Strulovici-Barel, Jason G Mezey

Am J Respir Crit Care Med· December 2018

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Ambient Pollution-related Reprogramming of the Human Small Airway Epithelial Transcriptome.
Sarah L O'Beirne, Sushila A Shenoy, Jacqueline Salit, Yael Strulovici-Barel, Robert J Kaner, Jason G Mezey

Am J Respir Crit Care Med· December 2018

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Corneal confocal microscopy: Neurologic disease biomarker in Friedreich ataxia.
Odelya E Pagovich, Mary L Vo, Zoe Z Zhao, Ioannis N Petropoulos, Michelle Yuan, Jason G Mezey

Ann Neurol· December 2018

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Point-of-care whole-exome sequencing of idiopathic male infertility.
Khalid A Fakhro, Haitham Elbardisi, Mohamed Arafa, Amal Robay, Juan L Rodriguez-Flores, Jason G Mezey

Genet Med· November 2018

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Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection.
Monica D Ramstetter, Sushila A Shenoy, Thomas D Dyer, Donna M Lehman, Joanne E Curran, Jason G Mezey

Am J Hum Genet· July 2018

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