Publications by authors named "Jason Muhitch"

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Comprehensive tumor-immune profiling reveals mediators of paradoxical immune sensitivity in sarcomatoid renal cell carcinoma.
Nicholas J Salgia, Adil Khan, Wilhelm M Aubrecht, Gavin C Twoey, Jacky Chow, Jason B Muhitch

Cancer Cell· November 2025

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Biological and Clinical Insight into the Prevention and Management of Metastatic Renal Cell Carcinoma with a Sarcomatoid Component.
Nicholas J Salgia, Yu Fujiwara, Bo Xu, Saby George, Jason B Muhitch

Eur Urol Focus· May 2025

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Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.
Angela L Hughson, Gary Hannon, Noah A Salama, Tara G Vrooman, Caroline A Stockwell, Jason B Muhitch

Mol Ther Nucleic Acids· December 2024

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Stratification of Patients with Renal Cell Carcinoma by the Abundance of Sarcomatoid Features Reveals Differences in Survival and the Underlying Pathobiology.
Nicholas J Salgia, Wilhelm M Aubrecht, Lin Wang, Bebu Ram, Brianna J Wasik, Jason B Muhitch

Eur Urol Oncol· October 2024

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A Bacterial and Ganglioside-based Nanoparticle Initiates Reprogramming of Macrophages and Promotes Antitumor Phenotypes.
Rydell Alvarez-Arzola, Liliana Oliver, Michelle M Messmer, Danielle Y F Twum, Kelvin P Lee, Jason B Muhitch

J Immunol· February 2024

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Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer.
Angela L Hughson, Gary Hannon, Noah A Salama, Tara G Vrooman, Caroline A Stockwell, Jason B Muhitch

bioRxiv· November 2023

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Tumor and immune remodeling following radiotherapy in human renal cell carcinoma.
Jacky Chow, Adil Khan, Madeline Gaudieri, Brianna J Wasik, Alexis Conway, Jason B Muhitch

J Immunother Cancer· April 2023

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Mitigating the prevalence and function of myeloid-derived suppressor cells by redirecting myeloid differentiation using a novel immune modulator.
Liliana Oliver, Rydell Alvarez, Raquel Diaz, Anet Valdés, Sean H Colligan, Jason B Muhitch

J Immunother Cancer· September 2022

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Augmenting antibody response to EGF-depleting immunotherapy: Findings from a phase I trial of CIMAvax-EGF in combination with nivolumab in advanced stage NSCLC.
Rachel Evans, Kelvin Lee, Paul K Wallace, Mary Reid, Jason Muhitch

Front Oncol· August 2022

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Iron accumulation typifies renal cell carcinoma tumorigenesis but abates with pathological progression, sarcomatoid dedifferentiation, and metastasis.
Christopher J Greene, Kristopher Attwood, Nitika J Sharma, Benjamin Balderman, Rongia Deng, Jason B Muhitch

Front Oncol· August 2022

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Phase Ib/II Study of Cetuximab plus Pembrolizumab in Patients with Advanced RAS Wild-Type Colorectal Cancer.
Christos Fountzilas, David L Bajor, Sarbajit Mukherjee, Joel Saltzman, Agnieszka K Witkiewicz, Jason B Muhitch

Clin Cancer Res· December 2021

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Radiation induces dynamic changes to the T cell repertoire in renal cell carcinoma patients.
Jacky Chow, Nicholas C Hoffend, Scott I Abrams, Thomas Schwaab, Anurag K Singh, Jason B Muhitch

Proc Natl Acad Sci U S A· September 2020

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thermal ablation augments antitumor efficacy of adoptive T cell therapy.
Fumito Ito, Trupti D Vardam, Michelle M Appenheimer, Kevin H Eng, Sandra O Gollnick, Jason B Muhitch

Int J Hyperthermia· November 2019

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Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma.
Jason B Muhitch, Nicholas C Hoffend, Gissou Azabdaftari, Austin Miller, Wiam Bshara

J Immunother Cancer· June 2019

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A Pilot Study of Stereotactic Body Radiation Therapy Combined with Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma.
Anurag K Singh, Timothy B Winslow, Mohammad Habiby Kermany, Vincent Goritz, Lilia Heit, Jason B Muhitch

Clin Cancer Res· September 2017

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Total cellular protein presence of the transcription factor IRF8 does not necessarily correlate with its nuclear presence.
Hans Minderman, Orla Maguire, Kieran L O'Loughlin, Jason Muhitch, Paul K Wallace

Methods· January 2017

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Unmasking targets of antitumor immunity via high-throughput antigen profiling.
Sebastiano Battaglia, Jason B Muhitch

Curr Opin Biotechnol· December 2016

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Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes.
Amy W Ku, Jason B Muhitch, Colin A Powers, Michael Diehl, Minhyung Kim

Elife· December 2016

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Immune Adjuvant Activity of Pre-Resectional Radiofrequency Ablation Protects against Local and Systemic Recurrence in Aggressive Murine Colorectal Cancer.
Fumito Ito, Amy W Ku, Mark J Bucsek, Jason B Muhitch, Trupti Vardam-Kaur

PLoS One· June 2016

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Intraoperative intravital microscopy permits the study of human tumour vessels.
Daniel T Fisher, Jason B Muhitch, Minhyung Kim, Kurt C Doyen, Paul N Bogner

Nat Commun· February 2016

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High-dose IL-2 for metastatic renal cell carcinoma: can the first antitumor immunotherapy be reinvented?
Jason B Muhitch, Thomas Schwaab

Immunotherapy· July 2015

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IL-17 promotes neutrophil entry into tumor-draining lymph nodes following induction of sterile inflammation.
Craig M Brackett, Jason B Muhitch, Sharon S Evans, Sandra O Gollnick

J Immunol· October 2013

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Preconditioning thermal therapy: flipping the switch on IL-6 for anti-tumour immunity.
Maryann E Mikucki, Daniel T Fisher, Amy W Ku, Michelle M Appenheimer, Jason B Muhitch

Int J Hyperthermia· August 2013

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A novel mouse model of isolated limb perfusion for extremity melanoma.
Minhyung Kim, Marta Camoriano, Jason B Muhitch, John M Kane, Joseph J Skitzki

J Surg Res· November 2012

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IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells.
Daniel T Fisher, Qing Chen, Joseph J Skitzki, Jason B Muhitch, Lei Zhou

J Clin Invest· October 2011

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