Publications by authors named "Jason Regules"

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Vaccine-induced antibodies to a C-terminal Plasmodium falciparum circumsporozoite protein epitope are associated with protection.
DeAnna J Friedman-Klabanoff, Travis L Jensen, Casey E Gelber, Richard S Pinapati, John C Tan, Jason A Regules

J Infect Dis· August 2025

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Safety and immunogenicity of an adjuvanted chikungunya virus virus-like particle (CHIKV VLP) vaccine in previous recipients of other alphavirus vaccines versus alphavirus vaccine-naive controls: an open-label, parallel-group, age-matched, sex-matched, phase 2 randomised controlled study.
Melinda J Hamer, James M McCarty, Benjamin C Pierson, Jason A Regules, Jason Mendy

Lancet Microbe· April 2025

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Recombinant Full-length Plasmodium falciparum Circumsporozoite Protein-Based Vaccine Adjuvanted With Glucopyranosyl Lipid A-Liposome Quillaja saponaria 21: Results of Phase 1 Testing With Malaria Challenge.
DeAnna J Friedman-Klabanoff, Andrea A Berry, Mark A Travassos, Mallory Shriver, Catherine Cox, Jason A Regules

J Infect Dis· June 2024

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A candidate antibody drug for prevention of malaria.
Katherine L Williams, Steve Guerrero, Yevel Flores-Garcia, Dongkyoon Kim, Kevin S Williamson, Jason A Regules

Nat Med· January 2024

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Novel antibody competition binding assay identifies distinct serological profiles associated with protection.
Jessica S Bolton, Randall S MacGill, Emily Locke, Jason A Regules, Elke S Bergmann-Leitner

Front Immunol· December 2023

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Late-presenting Plasmodium falciparum Malaria in a Non-Endemic Setting During COVID-19 Travel Restrictions.
Paul M Robben, Christopher R Dunbar, Elgin H Akin, Alexander Pichugin, Jason A Regules

Mil Med· May 2023

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Unglycosylated Soluble SARS-CoV-2 Receptor Binding Domain (RBD) Produced in Combined with the Army Liposomal Formulation Containing QS21 (ALFQ) Elicits Neutralizing Antibodies against Mismatched Variants.
Arasu Balasubramaniyam, Emma Ryan, Dallas Brown, Therwa Hamza, William Harrison, Jason Regules

Vaccines (Basel)· December 2022

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First-in-human assessment of safety and immunogenicity of low and high doses of Plasmodium falciparum malaria protein 013 (FMP013) administered intramuscularly with ALFQ adjuvant in healthy malaria-naïve adults.
Jack N Hutter, Paul M Robben, Christine Lee, Melinda Hamer, James E Moon, Jason Regules

Vaccine· September 2022

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Safety and immunogenicity of a plant-derived recombinant protective antigen (rPA)-based vaccine against Bacillus anthracis: A Phase 1 dose-escalation study in healthy adults.
Kristopher M Paolino, Jason A Regules, James E Moon, Richard C Ruck, Jason W Bennett

Vaccine· March 2022

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A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Nathan Beutler, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Randall S MacGill, Jason A Regules

PLoS Pathog· March 2022

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Assessing Prevalence and Transmission Rates of Malaria through Simultaneous Profiling of Antibody Responses against and Antigens.
Sidhartha Chaudhury, Jessica S Bolton, Leigh Anne Eller, Merlin Robb, Julie Ake, Jason A Regules

J Clin Med· March 2022

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Restricted valency (NPNA) repeats and junctional epitope-based circumsporozoite protein vaccines against Plasmodium falciparum.
Mark D Langowski, Farhat A Khan, Sofya Savransky, Dallas R Brown, Arasu Balasubramaniyam, Jason A Regules

NPJ Vaccines· January 2022

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A phase IIA extension study evaluating the effect of booster vaccination with a fractional dose of RTS,S/AS01 in a controlled human malaria infection challenge.
James E Moon, Melissa E Greenleaf, Jason A Regules, Muriel Debois, Elizabeth H Duncan

Vaccine· October 2021

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Serological profiles of pan-coronavirus-specific responses in COVID-19 patients using a multiplexed electro-chemiluminescence-based testing platform.
Sidhartha Chaudhury, Jack Hutter, Jessica S Bolton, Shilpa Hakre, Evelyn Mose, Jason A Regules

PLoS One· June 2021

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Comprehensive Data Integration Approach to Assess Immune Responses and Correlates of RTS,S/AS01-Mediated Protection From Malaria Infection in Controlled Human Malaria Infection Trials.
William Chad Young, Lindsay N Carpp, Sidhartha Chaudhury, Jason A Regules, Elke S Bergmann-Leitner

Front Big Data· June 2021

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The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection.
Ying Du, Ethan G Thompson, Julius Muller, Joseph Valvo, Jackie Braun, Jason A Regules

Front Immunol· March 2021

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A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01E and RTS,S/AS01B Delayed Fractional Dose Regimens in Malaria-Naive Adults.
James E Moon, Christian Ockenhouse, Jason A Regules, Johan Vekemans, Cynthia Lee

J Infect Dis· October 2020

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Development and characterization of a Zaire Ebola (ZEBOV) specific IgM ELISA.
Tanmaya Atre, Revell L Phillips, Kayvon Modjarrad, Jason A Regules, Elke S Bergmann-Leitner

J Immunol Methods· May 2019

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Mosquito Bite-Induced Controlled Human Malaria Infection with Plasmodium vivax or P. falciparum Generates Immune Responses to Homologous and Heterologous Preerythrocytic and Erythrocytic Antigens.
Cysha E Hall, Lisa M Hagan, Elke Bergmann-Leitner, Donna M Tosh, Jason W Bennett, Jason A Regules

Infect Immun· March 2019

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Delayed fractional dose regimen of the RTS,S/AS01 malaria vaccine candidate enhances an IgG4 response that inhibits serum opsonophagocytosis.
Sidhartha Chaudhury, Jason A Regules, Christian A Darko, Sheetij Dutta, Anders Wallqvist

Sci Rep· August 2017

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Protection against malaria by PfSPZ Vaccine.
Judith E Epstein, Kristopher M Paolino, Thomas L Richie, Martha Sedegah, Alexandra Singer, Jason Regules

JCI Insight· January 2017

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A monoclonal antibody-based immunoassay to measure the antibody response against the repeat region of the circumsporozoite protein of Plasmodium falciparum.
Kristina Radin, Frederic Clement, Erik Jongert, Yann G J Sterckx, Christian Ockenhouse, Jason Regules

Malar J· November 2016

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Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study.
Jason A Regules, Susan B Cicatelli, Jason W Bennett, Kristopher M Paolino, Patrick S Twomey

J Infect Dis· September 2016

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Circulating follicular T helper cells and cytokine profile in humans following vaccination with the rVSV-ZEBOV Ebola vaccine.
Fouzia Farooq, Kevin Beck, Kristopher M Paolino, Revell Phillips, Norman C Waters, Jason A Regules

Sci Rep· June 2016

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The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity.
Sidhartha Chaudhury, Christian F Ockenhouse, Jason A Regules, Sheetij Dutta, Anders Wallqvist

Malar J· May 2016

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