Publications by authors named "Jason Roland"

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A small molecule MST1/2 inhibitor accelerates murine liver regeneration with improved survival in models of steatohepatitis.
Ryan Watkins, Ana Gamo, Seung Hyuk Choi, Manoj Kumar, EeeLN Buckarma, Jason Roland

PNAS Nexus· March 2024

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Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3-]pyrimidine RET Inhibitors.
Casey J N Mathison, Yang Yang, John Nelson, Zhihong Huang, Jiqing Jiang, Jason Roland

ACS Med Chem Lett· December 2021

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A small molecule UPR modulator for diabetes identified by high throughput screening.
Valeria Marrocco, Tuan Tran, Siying Zhu, Seung Hyuk Choi, Ana M Gamo, Jason Roland

Acta Pharm Sin B· December 2021

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Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis.
Donatella Chianelli, Paul V Rucker, Jason Roland, David C Tully, John Nelson

J Med Chem· April 2020

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Efficacy and Tolerability of Pyrazolo[1,5-]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma.
Casey J N Mathison, Donatella Chianelli, Paul V Rucker, John Nelson, Jason Roland

ACS Med Chem Lett· April 2020

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Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.
Malina A Bakowski, Roohollah Kazem Shiroodi, Renhe Liu, Jason Olejniczak, Baiyuan Yang, Jason Roland

Sci Transl Med· May 2019

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A novel inhibitor of inducible NOS dimerization protects against cytokine-induced rat beta cell dysfunction.
Linlin Zhong, Tuan Tran, Tyler D Baguley, Sang Jun Lee, Adam Henke, Jason Roland

Br J Pharmacol· September 2018

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Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages.
Evan D Muse, Shan Yu, Chantle R Edillor, Jenhan Tao, Nathanael J Spann, Jason T Roland

Proc Natl Acad Sci U S A· May 2018

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Discovery of a Small-Molecule Modulator of Glycosaminoglycan Sulfation.
Sheldon T Cheung, Michelle S Miller, Reynand Pacoma, Jason Roland, Jian Liu

ACS Chem Biol· December 2017

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Dissociated sterol-based liver X receptor agonists as therapeutics for chronic inflammatory diseases.
Shan Yu, Sijia Li, Adam Henke, Evan D Muse, Bo Cheng, Jason Roland

FASEB J· July 2016

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KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro.
Anne-Marie Zeeman, Sandra M van Amsterdam, Case W McNamara, Annemarie Voorberg-van der Wel, Els J Klooster, Jason Roland

Antimicrob Agents Chemother· October 2014

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Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages.
Bin Zou, Advait Nagle, Arnab K Chatterjee, Seh Yong Leong, Liying Jocelyn Tan, Jason Roland

ACS Med Chem Lett· August 2014

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Targeting Plasmodium PI(4)K to eliminate malaria.
Case W McNamara, Marcus Cs Lee, Chek Shik Lim, Siau Hoi Lim, Jason Roland

Nature· December 2013

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Laparoscopic Roux-en-Y gastric bypass in patients with body mass index >70 kg/m2.
Jason C Roland, Bradley J Needleman, Peter Muscarella, C H Cook, Vimal K Narula

Surg Obes Relat Dis· January 2012

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Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Stephan Meister, David M Plouffe, Kelli L Kuhen, Ghislain M C Bonamy, Tao Wu, Jason Roland

Science· December 2011

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Seebach's conjunctive reagent enables double cyclizations.
Brent D Chandler, Jason T Roland, Yukai Li, Erik J Sorensen

Org Lett· June 2010

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Do gastrotomies require repair after endoscopic transgastric peritoneoscopy? A controlled study.
Simon Bergman, Daniel J Fix, Kevin Volt, Jason C Roland, Lynn Happel

Gastrointest Endosc· May 2010

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Extreme anemia in an injured Jehovah's Witness: a test of our understanding of the physiology of severe anemia and the threshold for blood transfusion.
Khashayar Vaziri, Jason C Roland, Linda L Robinson, H David Reines, Samir M Fakhry

J Trauma· July 2009

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Transgastric endoscopic peritoneoscopy does not require decontamination of the stomach in humans.
Vimal K Narula, Lynn C Happel, Kevin Volt, Simon Bergman, Jason C Roland

Surg Endosc· June 2009

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Right atrial rupture from blunt thoracic trauma in a 4-year-old child.
Jason Roland, Hani M Seoudi, Robert A Albus, Samir M Fakhry

Pediatr Emerg Care· March 2009

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Targeted parathyroidectomy: effectiveness and intraoperative rapid-parathormone dynamics.
Nader Sadeghi, Esma Akin, Jenny Yi Lee, Jason Roland, Stanley Knoll

Laryngoscope· November 2008

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Endolumenal fundoplication with EsophyX: the initial North American experience.
Simon Bergman, Dean J Mikami, Jeffrey W Hazey, Jason C Roland, Rebecca Dettorre

Surg Innov· September 2008

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Using steered molecular dynamics simulations and single-molecule force spectroscopy to guide the rational design of biomimetic modular polymeric materials.
Dora L Guzmán, Jason T Roland, Harindar Keer, Yen Peng Kong, Thorsten Ritz

Polymer (Guildf)· September 2008

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Endovascular management of a splenic artery aneurysm.
Jason Roland, Fred Brody, Anthony Venbrux

Surg Laparosc Endosc Percutan Tech· October 2007

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Image of the month. Basal cell carcinoma.
Jason Roland, Arnold Schwartz, Christine B Teal

Arch Surg· July 2007

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