Publications by authors named "Jason Somarelli"

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Novel niclosamide stearate prodrug therapeutic shows potential efficacy against naturally occurring canine osteosarcoma in a clinical feasibility study.
William C Eward, Kristina Pavic, Ivan Spasojevic, Jason A Somarelli, Hailey Brighton

Am J Vet Res· January 2026

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From sea to cell: Investigating the potential health impacts of marine plastic pollution in the Philippines.
Jasmine Santos, Beatrice Schleupner, Sophia Vincoff, Divya Dayanidhi, Ricardo Alindayu, Jason A Somarelli

Mar Pollut Bull· November 2025

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A memory-driven reinforcement learning model of phenotypic adaptation for anticipating therapeutic resistance in prostate cancer.
Zahra S Ghoreyshi, Shibjyoti Debnath, Pelumi D Olawuni, Andrew J Armstrong, Jason A Somarelli

bioRxiv· November 2025

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Dual targeting of conserved cell cycle and transcription programs in advanced colorectal cancer by fadraciclib.
Mohammad Zokaasadi, Wylie K Watlington, Divya L Dayanidhi, John B Mantyh, Gabrielle Rupprecht, Jason A Somarelli

Evol Med Public Health· October 2025

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Phylogenetic allometric scaling of near basal breathing frequency in terrestrial, semi-aquatic and aquatic mammals.
Andreas Fahlman, Elliot Stielstra, Ethan Wilstermann, Simon Rylaarsdam, Josefin Larsson, Jason Somarelli

Exp Physiol· September 2025

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Characterization of the genomic landscape of canine oral osteosarcoma reveals similarities with appendicular osteosarcoma.
Christopher Husted, Sarah Adrianowycz, Cornelia Peterson, Suzanne Bartholf DeWitt, Elinor K Karlsson, Jason A Somarelli

PLoS One· June 2025

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An informatics-based analysis platform identifies diverse microbial species with plastic-degrading potential.
Alexander Hong, Atharva Vispute, Serafina Turner, Rita Glazer, Zachary A Weishampel, Jason A Somarelli

Sci Total Environ· April 2025

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Mutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma.
Manas Sehgal, Sonali Priyadarshini Nayak, Sarthak Sahoo, Jason A Somarelli, Mohit Kumar Jolly

Cancer Biol Ther· December 2024

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Cell-cycle phase progression analysis identifies three unique phenotypes in soft tissue sarcoma.
Mark M Cullen, Alexander L Lazarides, Patricia D Pittman, Etienne M Flamant, Kathryn L Stoeber, Jason A Somarelli

BMC Cancer· October 2024

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Inhibition of Androgen Receptor Exposes Replication Stress Vulnerability in Prostate Cancer.
Carly S Williams, Xin Li, Hongjun Jang, Jay Ramanlal Anand, Won Young Lim, Jason A Somarelli

bioRxiv· October 2024

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Exploring versatile applications of a vacuum-assisted bone harvester in orthopedic surgery.
Kevin A Wu, Devika Shenoy, Elizabeth Sachs, Jason A Somarelli, Christian Pean

BMC Musculoskelet Disord· August 2024

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Increased prevalence of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer.
Sarthak Sahoo, Soundharya Ramu, Madhumathy G Nair, Maalavika Pillai, Beatriz P San Juan, Jason A Somarelli

iScience· July 2024

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The Known and Unknown: Investigating the Carcinogenic Potential of Plastic Additives.
Sophia Vincoff, Beatrice Schleupner, Jasmine Santos, Margaret Morrison, Newland Zhang, Jason A Somarelli

Environ Sci Technol· June 2024

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ATRX and Its Prognostic Significance in Soft Tissue Sarcoma.
Mark M Cullen, Warren Floyd, Bobby Dow, Beatrice Schleupner, Brian E Brigman, Jason A Somarelli

Sarcoma· May 2024

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Dynamical hallmarks of cancer: Phenotypic switching in melanoma and epithelial-mesenchymal plasticity.
Paras Jain, Maalavika Pillai, Atchuta Srinivas Duddu, Jason A Somarelli, Yogesh Goyal

Semin Cancer Biol· November 2023

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Multi-modal transcriptomic analysis unravels enrichment of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer.
Sarthak Sahoo, Soundharya Ramu, Madhumathy G Nair, Maalavika Pillai, Beatriz P San Juan, Jason A Somarelli

bioRxiv· October 2023

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Dynamical modeling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity.
Seemadri Subhadarshini, Sarthak Sahoo, Shibjyoti Debnath, Jason A Somarelli, Mohit Kumar Jolly

J Immunother Cancer· September 2023

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Transcriptomic Signatures Associated With Outcomes in Recurrent Prostate Cancer Treated With Salvage Radiation, Androgen-Deprivation Therapy, and Enzalutamide: Correlative Analysis of the STREAM Trial.
Rhonda L Bitting, Yuan Wu, Jason A Somarelli, James A Proudfoot, Yang Liu

JCO Precis Oncol· August 2023

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Atrx deletion impairs CGAS/STING signaling and increases sarcoma response to radiation and oncolytic herpesvirus.
Warren Floyd, Matthew Pierpoint, Chang Su, Rutulkumar Patel, Lixia Luo, Jason A Somarelli

J Clin Invest· July 2023

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Allometric scaling of metabolic rate and cardiorespiratory variables in aquatic and terrestrial mammals.
Rebecca S He, Stacy De Ruiter, Tristan Westover, Jason A Somarelli, Ashley M Blawas

Physiol Rep· June 2023

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Dynamical modelling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity.
Seemadri Subhadarshini, Sarthak Sahoo, Shibjyoti Debnath, Jason A Somarelli, Mohit Kumar Jolly

bioRxiv· June 2023

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A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer.
Kathryn E Ware, Beatrice C Thomas, Pelumi D Olawuni, Maya U Sheth, Nathan Hawkey, Jason A Somarelli

Front Mol Biosci· May 2023

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Corrigendum: Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition.
Divya L Dayanidhi, Jason A Somarelli, John B Mantyh, Gabrielle Rupprecht, Roham Salman Roghani

Front Med (Lausanne)· May 2023

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The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition.
Ayalur Raghu Subbalakshmi, Sarthak Sahoo, Prakruthi Manjunatha, Shaurya Goyal, Vignesh A Kasiviswanathan, Jason A Somarelli

J Biol Eng· March 2023

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Emergent dynamics of underlying regulatory network links EMT and androgen receptor-dependent resistance in prostate cancer.
Rashi Jindal, Abheepsa Nanda, Maalavika Pillai, Kathryn E Ware, Divyoj Singh, Jason A Somarelli

Comput Struct Biotechnol J· February 2023

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