Publications by authors named "Jason Spaeth"

Claim this Profile
C
CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity .
Sukrati Kanojia, Avinil Das Sharma, Rajani M George, Abigail G Taylor, Wenting Wu, Jason M Spaeth

Res Sq· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The SWI/SNF chromatin remodelling complex regulates pancreatic endocrine cell expansion and differentiation in mice in vivo.
Rebecca K Davidson, Wenting Wu, Sukrati Kanojia, Rajani M George, Kayla Huter, Jason M Spaeth

Diabetologia· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator .
Sukrati Kanojia, Rebecca K Davidson, Jason M Conley, Jerry Xu, Meredith Osmulski, Jason M Spaeth

Islets· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo.
Rebecca K Davidson, Sukrati Kanojia, Wenting Wu, Tatsuyoshi Kono, Jerry Xu, Jason M Spaeth

Diabetes· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Yin and Yang of Modulating β-Cell DNA Damage Response and Functional Mass.
Jason M Spaeth, Sangeeta Dhawan

Diabetes· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in β-cell function.
Rebecca K Davidson, Staci A Weaver, Nolan Casey, Sukrati Kanojia, Elise Hogarth, Jason M Spaeth

J Mol Endocrinol· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation.
Shane P Simonett, Sunyoung Shin, Jacob A Herring, Rhonda Bacher, Linsin A Smith, Jason Spaeth

J Clin Invest· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Contribution of Transcriptional Coregulators in the Maintenance of β-cell Function and Identity.
Rebecca K Davidson, Sukrati Kanojia, Jason M Spaeth

Endocrinology· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.
Jason M Spaeth, Jin-Hua Liu, Daniel Peters, Min Guo, Anna B Osipovich

Diabetes· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes.
Mark A Russell, Sambra D Redick, David M Blodgett, Sarah J Richardson, Pia Leete, Jason M Spaeth

Diabetes· May 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib.
Christopher S Wilson, Jason M Spaeth, Jay Karp, Blair T Stocks, Emilee M Hoopes

JCI Insight· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
Min Ju Park, Hailian Shen, Jason M Spaeth, Jaana H Tolvanen, Courtney Failor

J Biol Chem· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.
Jason M Spaeth, Manisha Gupte, Mark Perelis, Yu-Ping Yang, Holly Cyphert

Diabetes· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
E Danielle Dean, Mingyu Li, Nripesh Prasad, Scott N Wisniewski, Alison Von Deylen, Jason Spaeth

Cell Metab· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Elizabeth Conrad, Chunhua Dai, Jason Spaeth, Min Guo, Holly A Cyphert

Am J Physiol Endocrinol Metab· January 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.
Jason M Spaeth, Chad S Hunter, Lauren Bonatakis, Min Guo, Catherine A French

Diabetologia· August 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Mikko Turunen, Jason M Spaeth, Salla Keskitalo, Min Ju Park, Teemu Kivioja

Cell Rep· May 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling.
Haiying Zhou, Jason M Spaeth, Nam Hee Kim, Xuan Xu, Michael J Friez

Proc Natl Acad Sci U S A· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.
Philippe Krebs, Weiwei Fan, Yen-Hui Chen, Kimimasa Tobita, Michael R Downes, Jason M Spaeth

Proc Natl Acad Sci U S A· December 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mediator and human disease.
Jason M Spaeth, Nam Hee Kim, Thomas G Boyer

Semin Cell Dev Biol· September 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis