Publications by authors named "Jason Spence"

Claim this Profile
D
Dynamics of YAP localization and transcript activity in human oocytes and granulosa cells across early-stage folliculogenesis: an exploratory investigation.
Jordan H Machlin, Kate Potocsky, Robin E Kruger, Jason Spence, Vasantha Padmanabhan

J Assist Reprod Genet· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Surface expression of antitoxin on engineered bacteria neutralizes genotoxic colibactin in the gut.
Shaobo Yang, Zongqi Wang, Chengyuan Fang, Mengdi Yang, Saleh Khawaled, Jason R Spence

Nat Microbiol· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Publisher Correction: Surface expression of antitoxin on engineered bacteria neutralizes genotoxic colibactin in the gut.
Shaobo Yang, Zongqi Wang, Chengyuan Fang, Mengdi Yang, Saleh Khawaled, Jason R Spence

Nat Microbiol· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RUNX2 promotes epigenetic WNT signaling in inflamed intestinal epithelial cells.
Rodolfo I Cabrera-Silva, Zachary S Wilson, Jael Miranda, Shuling Fan, Michael Dame, Jason R Spence

bioRxiv· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Maternal Smoking and CC-16: Implications for Lung Development and COPD Across the Lifespan.
Joselyn Rojas-Quintero, Rosa Faner, Chia-Ying Chiu, Jeff T Kue, Yun Zhang, Jason Spence

Am J Respir Crit Care Med· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Clinical Interventions and Inflammatory Signaling Shape the Transcriptional and Cellular Architecture of the Early Postnatal Lung.
Tristan Frum, Angeline Wu, Marcela S Ymayo, Yu-Hwai Tsai, Sha Huang, Jason R Spence

bioRxiv· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids.
Kyoung Jo, Zong-Yuan Liu, Gauri Patel, Zhiyuan Yu, LiAng Yao, Jason Spence

bioRxiv· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human-mouse cross-species comparison identifies common and unique aspects of intestinal mesenchyme development.
Kelli Johnson, Xiangning Dong, Zhiwei Xiao, Hamza Islam, Meghan Anderman, Jason R Spence

bioRxiv· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A scalable long-term model of human colonic epithelium with continuous barrier function.
Ashley J Cuttitta, Sophia R Meyer, Tristan Frum, Bhargavasai Gunuguntla, Angeline Wu, Jason R Spence

bioRxiv· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Recent evolution of the developing human intestine affects metabolic and barrier functions.
Qianhui Yu, Umut Kilik, Stefano Secchia, Lukas Adam, Yu-Hwai Tsai, Jason R Spence

Science· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fibroblast lipid metabolism through ACSL4 regulates epithelial sensitivity to ferroptosis in IBD.
Wesley Huang, Yuezhong Zhang, Nupur K Das, Sumeet Solanki, Chesta Jain, Jason R Spence

Nat Metab· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mapping mesenchymal diversity in the developing human intestine and organoids.
Kelli F Johnson, Xiangning Dong, Yu-Hwai Tsai, Angeline Wu, Sydney G Clark, Jason R Spence

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SOX9 suppresses colon cancer via inhibiting epithelial-mesenchymal transition and SOX2 induction.
Ying Feng, Ningxin Zhu, Karan Bedi, Jinju Li, Chamila Perera, Jason R Spence

J Clin Invest· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lysophosphatidic acid and sphingosine-1-phosphate are apical polarity cues in multiple organoid systems.
Andrew M Tidball, Jinghui Luo, J Clayton Walker, Charlotte Y Yang, Keithan Lee, Ryan C Spencer, Jason R Spence

Cell Rep· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An integrated transcriptomic cell atlas of human endoderm-derived organoids.
Quan Xu, Lennard Halle, Soroor Hediyeh-Zadeh, Merel Kuijs, Rya Riedweg, Jason R Spence

Nat Genet· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature.
Charlie J Childs, Holly M Poling, Kevin Chen, Yu-Hwai Tsai, Angeline Wu, Ryan C Spencer, Jason R Spence

Cell Stem Cell· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels.
Madeline K Eiken, Charlie J Childs, Lindy K Brastrom, Tristan Frum, Eleanor M Plaster, Ryan C Spencer, Jason R Spence

Stem Cell Reports· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Polymer design of microwell hydrogels influences epithelial-mesenchymal interactions during human bronchosphere formation.
Madeline K Eiken, Justin E Levine, Shinyeong Lee, Samantha Lukpat, Eleanor M Plaster, Jason R Spence

Adv Nanobiomed Res· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Neutrophil prime unique transcriptional responses in intestinal organoids during infection with nontyphoidal serovars.
Anna-Lisa E Lawrence, Ryan P Berger, David R Hill, Sha Huang, Veda K Yadagiri, Jason R Spence

mSphere· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function.
Paramita Ray, Sangeeta Jaiswal, Daysha Ferrer-Torres, Zhuwen Wang, Derek Nancarrow, Jason R Spence

Mol Cancer Res· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
APOE-NOTCH axis governs elastogenesis during human cardiac valve remodeling.
Ziyi Liu, Yu Liu, Zhiyun Yu, Cheng Tan, Nicole Pek, Jason R Spence

Nat Cardiovasc Res· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung.
Jiapeng Li, Daniel Macedo de Melo Jorge, Weiwen Wang, Shuxin Sun, Tristan Frum, Jason R Spence

J Med Chem· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A patterned human neural tube model using microfluidic gradients.
Xufeng Xue, Yung Su Kim, Alfredo-Isaac Ponce-Arias, Richard O'Laughlin, Robin Zhexuan Yan, Jason R Spence

Nature· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels.
Madeline K Eiken, Charlie J Childs, Lindy K Brastrom, Tristan Frum, Eleanor M Plaster, Jason R Spence

bioRxiv· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Near-Infrared In Vivo Imaging of Claudin-1 Expression by Orthotopically Implanted Patient-Derived Colonic Adenoma Organoids.
Sangeeta Jaiswal, Fa Wang, Xiaoli Wu, Tse-Shao Chang, Ahmad Shirazi, Jason R Spence

Diagnostics (Basel)· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis