Publications by authors named "Jasper Chan"

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E
Enhanced surveillance, subtyping, and host adaptation analysis reveal genotype-wide zoonotic potential of rat hepatitis E virus.
Kelvin Hon-Yin Lo, Siu-Fung Stanley Ho, Estie Hon-Kiu Shun, Shusheng Wu, Cyril Chik-Yan Yip, Wan-Mui Chan, Jasper Fuk-Woo Chan

J Hepatol· January 2026

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Reverse genetics-derived cattle H5N1 virus from Clade 2.3.4.4b shows enhanced systemic infectivity and pathogenicity than an older Clade 1 H5N1 virus in BALB/c mice.
Na Xiao, Xiang Yong Oong, Yanxia Chen, Can Li, Howard Chun-Ho Chung, Jasper Fuk-Woo Chan

Emerg Microbes Infect· December 2025

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Enhanced replication of a contemporary avian influenza A H9N2 virus in human respiratory organoids.
Lin-Lei Chen, Jonathan Daniel Ip, Wan-Mui Chan, Stephanie Joy-Ann Lam, Rhoda Cheuk-Ying Leung, Kwok-Hung Chan, Jasper Fuk-Woo Chan

Emerg Microbes Infect· December 2025

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Structure-guided discovery of a small molecule inhibitor of SARS-CoV-2 main protease with potent and antiviral activities.
Shuofeng Yuan, Juan Wang, Xiaohong Sang, Yubin Xie, Yong Feng, Chris Chung-Sing Chan, Jasper Fuk-Woo Chan

J Virol· December 2025

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Development of monoclonal antibodies against E1 protein of Chikungunya virus.
Kun Wen, Zhihong Zhou, Peipei Xu, Biao Di, Jialing Song, Jasper Fuk-Woo Chan

PLoS Negl Trop Dis· December 2025

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Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1.
Jialu Shi, Xiaoyu Zhao, Xiaohui Jin, Jiayan Li, Yuanchen Liu, Wan-Mui Chan, Jasper Fuk-Woo Chan

Nat Commun· December 2025

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Author Correction: An orally available M/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.
Huiping Shuai, Jingxin Qiao, Chaemin Yoon, Guo Zhang, Yuxin Hou, Jasper Fuk-Woo Chan

Nat Commun· December 2025

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Retrospective Analysis of Graft Loss Risk in Patients with BK Polyomavirus Associated Nephropathy in Relation to Rejection Status in a Multicentre Cohort with Regular Surveillance of BK Polyomavirus and Donor-Specific Antibody.
Maggie Kam-Man Ma, Jasper Fuk-Woo Chan, Tsz-Ling Ho, Darwin Chi-Kwan Lam, William Lee

Am J Nephrol· November 2025

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Discovery of a potent covalent inhibitor that unusually distorts the catalytic dyad of SARS-CoV-2 main protease.
Juan Wang, Xiaohong Sang, Wenyan Zheng, Jasper Fuk-Woo Chan, Jiao Zhou, Aaron Ciechanover

J Virol· October 2025

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Author Correction: Identification and characterization of GLDC as host susceptibility gene to severe influenza.
Jie Zhou, Dong Wang, Bosco Ho-Yin Wong, Cun Li, Vincent Kwok-Man Poon, Jasper Fuk-Woo Chan

EMBO Mol Med· August 2025

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Comparative performance of a commercial and in-house Mp1p antigen-detecting enzyme immunoassay for the rapid diagnosis of talaromycosis.
Joseph Barwatt, Lottie Brown, Nguyen Thi Mai Thu, Paula Gonzalez, Sruthi Venugopalan, Jasper Fuk-Woo Chan

PLoS Negl Trop Dis· August 2025

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An orally available M/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.
Huiping Shuai, Jingxin Qiao, Chaemin Yoon, Guo Zhang, Yuxin Hou, Jasper Fuk-Woo Chan

Nat Commun· July 2025

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Dual-Genotype Orientia tsutsugamushi Infections, Hainan Island, China, 2023.
Yi Niu, Siqi Chen, Gaoyu Wang, Yijia Guo, Nan Ge, Jasper Fuk-Woo Chan

Emerg Infect Dis· June 2025

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Recent Advances in the Diagnosis of Talaromycosis.
Lottie Brown, Ngo Thi Hoa, Vo Trieu Ly, Linghua Li, Cunwei Cao, Jasper Fuk-Woo Chan

Clin Infect Dis· June 2025

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Prevalence of (rat hepatitis E virus) in humans and rats in China.
Xiuji Cui, Jianwen Situ, Ting Tang, Zhiyu Li, Dongzhui Chen, Jasper Fuk-Woo Chan

JHEP Rep· May 2025

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BRD9 functions as an HIV-1 latency regulatory factor.
Tsz-Yat Luk, Lok-Yan Yim, Runhong Zhou, Yufei Mo, Huarong Huang, Jasper Fuk-Woo Chan

Proc Natl Acad Sci U S A· May 2025

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Patient-centric analysis of Orientia tsutsugamushi spatial diversity patterns across Hainan Island, China.
Chuanning Tang, Yi Huang, Gaoyu Wang, Liying Xue, Xiaoyuan Hu, Jasper Fuk-Woo Chan

PLoS Negl Trop Dis· March 2025

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Epidemiology and Genetic Evolutionary Analysis of Influenza Virus Among Children in Hainan Island, China, 2021-2023.
Meng Chang, Shengjie Shi, Yan Jin, Gaoyu Wang, Ruoyan Peng, Jasper Fuk-Woo Chan

Pathogens· February 2025

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Development and validation of the Post-COVID Symptom Scale for Children/Youth (PCSS-C/Y).
Winnie Wan Yee Tso, Yuliang Wang, Daniel Yee Tak Fong, Mike Yat Wah Kwan, Patrick Ip, Jasper Fuk Woo Chan, Jason Ying Kuen Chan

Eur J Pediatr· December 2024

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(1, 3)-beta-D-Glucan in bronchoalveolar lavage fluid: a useful biomarker in diagnosis of invasive pulmonary infection caused by Hormographiella aspergillata?
Haiyan Ye, Jinhui He, Jing Huang, Patrick Chu, Junru Liu, Jasper Fuk-Woo Chan

Diagn Pathol· December 2024

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Human respiratory organoids sustained reproducible propagation of human rhinovirus C and elucidation of virus-host interaction.
Cun Li, Yifei Yu, Zhixin Wan, Man Chun Chiu, Jingjing Huang, Jasper Fuk-Woo Chan

Nat Commun· December 2024

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An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.
Hin Chu, Huiping Shuai, Jingxin Qiao, Chaemin Yoon, Guo Zhang, Jasper Chan

Res Sq· November 2024

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Chronic lung inflammation and CK14+ basal cell proliferation induce persistent alveolar-bronchiolization in SARS-CoV-2-infected hamsters.
Can Li, Na Xiao, Wenchen Song, Alvin Hiu-Chung Lam, Feifei Liu, Jasper Fuk-Woo Chan

EBioMedicine· October 2024

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Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3.
Yuanchen Liu, Xiaoyu Zhao, Jialu Shi, Yajie Wang, Huan Liu, Wan-Mui Chan, Jasper Fuk-Woo Chan

Nat Commun· October 2024

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Epidemiology of Human Parainfluenza Virus Infections among Pediatric Patients in Hainan Island, China, 2021-2023.
Meifang Xiao, Afreen Banu, Xiangyue Zeng, Shengjie Shi, Ruoyan Peng, Jasper Fuk-Woo Chan, Meng Chang

Pathogens· August 2024

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