Publications by authors named "Javad Nazarian"

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First-in-human sonodynamic therapy with ALA for pediatric diffuse intrinsic pontine glioma: a phase 1/2 study using low-intensity focused ultrasound : Technical communication.
Hasan R Syed, Lindsay Kilburn, Adriana Fonseca, Javad Nazarian, Chima Oluigbo, John S Myseros, Roger J Packer, Robert F Keating

J Neurooncol· April 2023

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A microfluidic platform for the co-culturing of microtissues with continuously recirculating suspension cells.
Christian Lohasz, Tamara Häfeli, Dzhansu Hasanova, Lisa Hölting, Michal Rudnik, Javad Nazarian

Microsyst Nanoeng· October 2025

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Decoding the cancer cell proteome: A delicate equilibrium with the genome and epigenome.
Ryan J Duchatel, Javad Nazarian

Neuro Oncol· September 2025

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Dual treatment with Val-083 and AZD1775 shows potent anti-tumor activity in diffuse midline glioma models.
Bavani Subramaniam, Debasish Roy, Ayda Woldegerima, Wai Chin Chong, Justyna M Przystal, Javad Nazarian

NPJ Precis Oncol· July 2025

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Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high grade glioma models.
Jessica B Foster, Peter J Madsen, Kyra Harvey, Crystal Griffin, Allison Stern, Javad Nazarian

Neuro Oncol· May 2025

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Correction: Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, Sebastian M Waszak, Stefan R Sweha, Javad Nazarian

Cancer Discov· March 2025

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The T cell receptor landscape of childhood brain tumors.
Itay Raphael, Zujian Xiong, Chaim T Sneiderman, Rebecca A Raphael, Moshe Mash, Javad Nazarian

Sci Transl Med· March 2025

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Single-molecule systems for the detection and monitoring of plasma-circulating nucleosomes and oncoproteins in diffuse midline glioma.
Nir Erez, Noa Furth, Vadim Fedyuk, Jack Wadden, Rayan Aittaleb, Javad Nazarian

Cell Rep Med· January 2025

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The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models.
Daniel de la Nava, Iker Ausejo-Mauleon, Virginia Laspidea, Marisol Gonzalez-Huarriz, Andrea Lacalle, Javad Nazarian

Neuro Oncol· August 2024

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The role of focused ultrasound for pediatric brain tumors: current insights and future implications on treatment strategies.
Kelsi M Chesney, Gregory F Keating, Nirali Patel, Lindsay Kilburn, Adriana Fonseca, Javad Nazarian

Childs Nerv Syst· August 2024

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Transcriptomic Meta-analysis Identifies Long Non-Coding RNAs Mediating Zika's Oncolytic Impact in Glioblastoma Multiforme.
Youssef A Kousa, Shriya Singh, Allison Horvath, Federica Tomasso, Javad Nazarian

bioRxiv· August 2024

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Tumor volume features predict survival outcomes for patients diagnosed with diffuse intrinsic pontine glioma.
D'Andre Spencer, Erin R Bonner, Carlos Tor-Díez, Xinyang Liu, Kristen Bougher, Javad Nazarian

Neurooncol Adv· August 2024

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A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered.
Evangeline R Jackson, Mika L Persson, Cameron J Fish, Izac J Findlay, Sabine Mueller, Javad Nazarian

Neuro Oncol· May 2024

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H3K27M mutant glioma: Disease definition and biological underpinnings.
Amanda M Saratsis, Truman Knowles, Antonela Petrovic, Javad Nazarian

Neuro Oncol· May 2024

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Rational combination platform trial design for children and young adults with diffuse midline glioma: A report from PNOC.
Sabine Mueller, Cassie Kline, Andrea Franson, Jasper van der Lugt, Michael Prados, Javad Nazarian

Neuro Oncol· May 2024

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Zebrafish-A Suitable Model for Rapid Translation of Effective Therapies for Pediatric Cancers.
Debasish Roy, Bavani Subramaniam, Wai Chin Chong, Miriam Bornhorst, Roger J Packer, Javad Nazarian

Cancers (Basel)· March 2024

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H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells.
Katarzyna B Leszczynska, Amanda Freitas-Huhtamäki, Chinchu Jayaprakash, Monika Dzwigonska, Francisca N L Vitorino, Javad Nazarian

Cell Rep· February 2024

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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
Ryan J Duchatel, Evangeline R Jackson, Sarah G Parackal, Dylan Kiltschewskij, Izac J Findlay, Javad Nazarian

J Clin Invest· February 2024

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A road map for the treatment of pediatric diffuse midline glioma.
Carl Koschmann, Wajd N Al-Holou, Marta M Alonso, Jamie Anastas, Pratiti Bandopadhayay, Javad Nazarian

Cancer Cell· January 2024

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An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
Stephanie M Casillo, Taylor A Gatesman, Akanksha Chilukuri, Srinidhi Varadharajan, Brenden J Johnson, Javad Nazarian

Cell Rep· January 2024

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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.
Iker Ausejo-Mauleon, Sara Labiano, Daniel de la Nava, Virginia Laspidea, Marta Zalacain, Javad Nazarian

Cancer Cell· November 2023

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Single-molecule systems for detection and monitoring of plasma circulating nucleosomes and oncoproteins in Diffuse Midline Glioma.
Nir Erez, Noa Furth, Vadim Fedyuk, Jack Wadden, Rayan Aittaleb, Javad Nazarian

bioRxiv· November 2023

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Bridging the age gap: a review of molecularly informed treatments for glioma in adolescents and young adults.
Annette Weiser, Astrid Sanchez Bergman, Charbel Machaalani, Julie Bennett, Patrick Roth, Javad Nazarian

Front Oncol· September 2023

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Pan-cancer atlas of somatic core and linker histone mutations.
Erin R Bonner, Adam Dawood, Heather Gordish-Dressman, Augustine Eze, Surajit Bhattacharya, Javad Nazarian

NPJ Genom Med· August 2023

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OpenPBTA: The Open Pediatric Brain Tumor Atlas.
Joshua A Shapiro, Krutika S Gaonkar, Stephanie J Spielman, Candace L Savonen, Chante J Bethell, Javad Nazarian

Cell Genom· July 2023

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