Publications by authors named "Javier Dotor"

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Clinical development complexity of TGF-β inhibition: From fibrosis to cancer immunotherapy.
Gabriel Gallo-Oller, María Isabel Guillén-Antonini, Javier Dotor

Int Rev Cell Mol Biol· July 2025

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P144 a Transforming Growth Factor Beta Inhibitor Peptide, Generates Antifibrogenic Effects in a Radiotherapy Induced Fibrosis Model.
Sebastián Cruz-Morande, Javier Dotor, Mikel San-Julian

Curr Oncol· April 2022

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Transforming growth factor beta (TGF-β) activity in immuno-oncology studies.
Gabriel Gallo-Oller, Marianna Di Scala, Fernando Aranda, Javier Dotor

Methods Enzymol· June 2021

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A new background subtraction method for Western blot densitometry band quantification through image analysis software.
Gabriel Gallo-Oller, Raquel Ordoñez, Javier Dotor

J Immunol Methods· June 2018

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In vitro cell response on CP-Ti surfaces functionalized with TGF-β1 inhibitory peptides.
Pablo Sevilla, Andrea Cirera, Javier Dotor, Francisco Javier Gil, Pablo Galindo-Moreno

J Mater Sci Mater Med· May 2018

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P144, a Transforming Growth Factor beta inhibitor peptide, generates antitumoral effects and modifies SMAD7 and SKI levels in human glioblastoma cell lines.
Gabriel Gallo-Oller, Arabel Vollmann-Zwerenz, Bárbara Meléndez, Juan A Rey, Peter Hau, Javier Dotor

Cancer Lett· October 2016

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Effect of P144® (Anti-TGF-β) in an "In Vivo" Human Hypertrophic Scar Model in Nude Mice.
Shan Shan Qiu, Javier Dotor, Bernardo Hontanilla

PLoS One· June 2016

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Mesothelial-to-mesenchymal transition in the pathogenesis of post-surgical peritoneal adhesions.
Pilar Sandoval, José A Jiménez-Heffernan, Gonzalo Guerra-Azcona, María L Pérez-Lozano, Ángela Rynne-Vidal, Javier Dotor

J Pathol· May 2016

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Surface immobilization and bioactivity of TGF-β1 inhibitor peptides for bone implant applications.
Pablo Sevilla, Kyle V Vining, Javier Dotor, Daniel Rodriguez, F Javier Gil

J Biomed Mater Res B Appl Biomater· February 2016

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Co-migration of colon cancer cells and CAFs induced by TGFβ₁ enhances liver metastasis.
Idoia Gonzalez-Zubeldia, Javier Dotor, Miriam Redrado, Anne-Marie Bleau, Irene Manrique

Cell Tissue Res· March 2015

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Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases.
José Medina-Echeverz, Jessica Fioravanti, Nancy Díaz-Valdés, Kathrin Frank, Fernando Aranda, Javier Dotor

PLoS One· January 2015

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A pathogenetic role for endothelin-1 in peritoneal dialysis-associated fibrosis.
Oscar Busnadiego, Jesús Loureiro-Álvarez, Pilar Sandoval, David Lagares, Javier Dotor

J Am Soc Nephrol· January 2015

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The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes.
Patricia Sanz-Ramos, Javier Dotor, Iñigo Izal-Azcárate

Cell Mol Biol Lett· December 2014

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Quantitative method for in vitro matrigel invasiveness measurement through image analysis software.
Gabriel Gallo-Oller, Juan A Rey, Javier Dotor, Javier S Castresana

Mol Biol Rep· October 2014

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Improved Chondrogenic Capacity of Collagen Hydrogel-Expanded Chondrocytes: In Vitro and in Vivo Analyses.
Patricia Sanz-Ramos, Julio Duart, María Victoria Rodríguez-Goñi, Mikel Vicente-Pascual, Javier Dotor

J Bone Joint Surg Am· July 2014

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Density and duration of pneumococcal carriage is maintained by transforming growth factor β1 and T regulatory cells.
Daniel R Neill, William R Coward, Jenna F Gritzfeld, Luke Richards, Francesc J Garcia-Garcia, Javier Dotor

Am J Respir Crit Care Med· May 2014

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Combined targeting of TGF-β1 and integrin β3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer.
Elizabeth Salvo, Saray Garasa, Javier Dotor, Xabier Morales, Rafael Peláez

Mol Cancer· May 2014

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Transforming growth factor-beta inhibition reduces progression of early choroidal neovascularization lesions in rats: P17 and P144 peptides.
Javier Zarranz-Ventura, Patricia Fernández-Robredo, Sergio Recalde, Angel Salinas-Alamán, Francisco Borrás-Cuesta, Javier Dotor

PLoS One· January 2014

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Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis.
Pilar Sandoval, Jose Antonio Jiménez-Heffernan, Ángela Rynne-Vidal, María Luisa Pérez-Lozano, Álvaro Gilsanz, Javier Dotor

J Pathol· December 2013

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A synthetic peptide from transforming growth factor-β₁ type III receptor inhibits NADPH oxidase and prevents oxidative stress in the kidney of spontaneously hypertensive rats.
Ana Baltanás, José Luis Miguel-Carrasco, Gorka San José, Carolina Cebrián, María U Moreno, Javier Dotor

Antioxid Redox Signal· November 2013

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GDF5 regulates TGFß-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFß peptides.
Francesca Margheri, Nicola Schiavone, Laura Papucci, Lucia Magnelli, Simona Serratì, Javier Dotor

PLoS One· May 2013

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Systemic sclerosis endothelial cells recruit and activate dermal fibroblasts by induction of a connective tissue growth factor (CCN2)/transforming growth factor β-dependent mesenchymal-to-mesenchymal transition.
Simona Serratì, Anastasia Chillà, Anna Laurenzana, Francesca Margheri, Elisa Giannoni, Javier Dotor

Arthritis Rheum· January 2013

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Blockade of TGF-β 1 signalling inhibits cardiac NADPH oxidase overactivity in hypertensive rats.
José Luis Miguel-Carrasco, Ana Baltanás, Carolina Cebrián, María U Moreno, Begoña López, Javier Dotor

Oxid Med Cell Longev· October 2012

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Modulation of regulatory T-cell activity in combination with interleukin-12 increases hepatic tolerogenicity in woodchucks with chronic hepatitis B.
Itziar Otano, Lester Suarez, Javier Dotor, Manuela Gonzalez-Aparicio, Julien Crettaz

Hepatology· August 2012

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Transforming growth factor-β inhibition decreases diode laser-induced choroidal neovascularization development in rats: P17 and P144 peptides.
Sergio Recalde, Javier Zarranz-Ventura, Patricia Fernández-Robredo, Pío J García-Gómez, Angel Salinas-Alamán, Javier Dotor

Invest Ophthalmol Vis Sci· September 2011

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