Publications by authors named "Javier Florido"

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Melatonin Overcomes Cancer Multidrug Resistance by Downregulating ABCB1 Expression and Modulating Mitochondrial Function.
Alba López-Rodríguez, Laura Martinez-Ruiz, Raquel Morales-Gallel, Javier Florido, Fabiola Bermejo-Casares

J Pineal Res· November 2025

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E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development.
Michela Di Michele, Aurore Attina, Pierre-François Roux, Imène Tabet, Sophie Laguesse, Javier Florido

Nat Commun· January 2025

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Mucosa-like differentiation of head and neck cancer cells is inducible and drives the epigenetic loss of cell malignancy.
Felix Oppel, Sarah Gendreizig, Laura Martinez-Ruiz, Javier Florido, Alba López-Rodríguez

Cell Death Dis· October 2024

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Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress.
Laura Martinez-Ruiz, Javier Florido, César Rodriguez-Santana, Alba López-Rodríguez, Ana Guerra-Librero

Biomed Pharmacother· November 2023

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Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin.
Laura Martinez-Ruiz, Alba López-Rodríguez, Javier Florido, Cesar Rodríguez-Santana, José M Rodríguez Ferrer

Biomed Pharmacother· November 2023

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The Relationship between Clock Genes, Sirtuin 1, and Mitochondrial Activity in Head and Neck Squamous Cell Cancer: Effects of Melatonin Treatment.
César Rodríguez-Santana, Alba López-Rodríguez, Laura Martinez-Ruiz, Javier Florido, Olga Cela

Int J Mol Sci· October 2023

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Primary head and neck cancer cell cultures are susceptible to proliferation of Epstein-Barr virus infected lymphocytes.
Senyao Shao, Lars Uwe Scholtz, Sarah Gendreizig, Laura Martínez-Ruiz, Javier Florido

BMC Cancer· January 2023

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Role of Melatonin in Cancer: Effect on Clock Genes.
César Rodríguez-Santana, Javier Florido, Laura Martínez-Ruiz, Alba López-Rodríguez, Darío Acuña-Castroviejo

Int J Mol Sci· January 2023

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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport.
Javier Florido, Laura Martinez-Ruiz, César Rodriguez-Santana, Alba López-Rodríguez, Agustín Hidalgo-Gutiérrez

J Pineal Res· October 2022

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Understanding the Mechanism of Action of Melatonin, Which Induces ROS Production in Cancer Cells.
Javier Florido, César Rodriguez-Santana, Laura Martinez-Ruiz, Alba López-Rodríguez, Darío Acuña-Castroviejo

Antioxidants (Basel)· August 2022

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Role of c-miR-21, c-miR-126, Redox Status, and Inflammatory Conditions as Potential Predictors of Vascular Damage in T2DM Patients.
Gabriela C López-Armas, Arailym Yessenbekova, Rocío E González-Castañeda, Kevin J Arellano-Arteaga, Ana Guerra-Librero, Javier Florido

Antioxidants (Basel)· August 2022

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Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function.
Ana Guerra-Librero, Beatriz I Fernandez-Gil, Javier Florido, Laura Martinez-Ruiz, César Rodríguez-Santana

Antioxidants (Basel)· April 2021

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Protective Effects of Melatonin on the Skin: Future Perspectives.
Iryna Rusanova, Laura Martínez-Ruiz, Javier Florido, César Rodríguez-Santana, Ana Guerra-Librero

Int J Mol Sci· October 2019

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Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy.
Beatriz I Fernandez-Gil, Ana Guerra-Librero, Ying-Qiang Shen, Javier Florido, Laura Martínez-Ruiz

Oxid Med Cell Longev· April 2019

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Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Ying-Qiang Shen, Ana Guerra-Librero, Beatriz I Fernandez-Gil, Javier Florido, Sergio García-López

J Pineal Res· April 2018

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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Nadia Cobo-Vuilleumier, Petra I Lorenzo, Noelia García Rodríguez, Irene de Gracia Herrera Gómez, Esther Fuente-Martin, Javier P Florido

Nat Commun· April 2018

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Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function.
Miguel Mendivil-Perez, Viviana Soto-Mercado, Ana Guerra-Librero, Beatriz I Fernandez-Gil, Javier Florido

J Pineal Res· September 2017

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Oral Mucositis: Melatonin Gel an Effective New Treatment.
Ahmed Esmat Abdel Moneim, Ana Guerra-Librero, Javier Florido, Ying-Qiang Shen, Beatriz Fernández-Gil

Int J Mol Sci· May 2017

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Melatonin protects rats from radiotherapy-induced small intestine toxicity.
Beatriz Fernández-Gil, Ahmed E Abdel Moneim, Francisco Ortiz, Ying-Qiang Shen, Viviana Soto-Mercado, Javier Florido

PLoS One· April 2017

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267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation.
Joaquín Dopazo, Alicia Amadoz, Marta Bleda, Luz Garcia-Alonso, Alejandro Alemán, Javier P Florido

Mol Biol Evol· May 2016

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ngsCAT: a tool to assess the efficiency of targeted enrichment sequencing.
Francisco J López-Domingo, Javier P Florido, Antonio Rueda, Joaquín Dopazo, Javier Santoyo-Lopez

Bioinformatics· June 2014

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Optimizing multiple sequence alignments using a genetic algorithm based on three objectives: structural information, non-gaps percentage and totally conserved columns.
Francisco M Ortuño, Olga Valenzuela, Fernando Rojas, Hector Pomares, Javier P Florido

Bioinformatics· September 2013

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Predicting the accuracy of multiple sequence alignment algorithms by using computational intelligent techniques.
Francisco M Ortuño, Olga Valenzuela, Hector Pomares, Fernando Rojas, Javier P Florido

Nucleic Acids Res· January 2013

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