Publications by authors named "Javier Inserte"

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Correction: IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): a small animal acute myocardial infarction randomized-controlled multicenter study on the effect of ischemic preconditioning.
Sauri Hernandez-Resendiz, Reinis Vilskersts, David Aluja, Ioanna Andreadou, Péter Bencsik, Javier Inserte

Basic Res Cardiol· December 2025

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Insights into the causal role of diesel exhaust particles in ventricular arrhythmogenesis: protective effects of antioxidant cerium oxide nanoparticles.
Freddy G Ganse, Lena M Ernst, Cristina Rodríguez, Marisol Ruiz-Meana, Javier Inserte

Part Fibre Toxicol· December 2025

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Extracellular RNA drives TNF-α/TNF-receptor-1 mediated cardiac ischemia/reperfusion injury: Mechanistic insights and therapeutic potential of RNase1.
Hector A Cabrera-Fuentes, Marisol Ruiz-Meana, Guillermo Barreto, Victor L Serebruany, Jose T Sánchez-Vega, Javier Inserte

Pharmacol Res· November 2025

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Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis-responsive gene with roles in ventricular structure and neuromuscular function.
Gisel Barés, Aida Beà, Anna Sancho-Balsells, Juan G Valero, David Aluja, Javier Inserte

FEBS J· October 2025

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Cardiac intermediary metabolism in heart failure: substrate use, signalling roles and therapeutic targets.
Mathias Mericskay, Coert J Zuurbier, Lisa C Heather, Anja Karlstaedt, Javier Inserte

Nat Rev Cardiol· October 2025

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Involvement of connexin 43 in myocardial ischemia-reperfusion injury.
Marisol Ruiz-Meana, Javier Inserte, Marta Consegal, Antonio Rodríguez-Sinovas

Cell Tissue Res· September 2025

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Iron Deficiency Is Associated With Impaired Myocardial Reperfusion in ST-Segment-Elevation Myocardial Infarction: Influence of the Definition Used.
José A Barrabés, Javier Inserte, Laura Castellote, Irene Buera, Laia Milà

J Am Heart Assoc· June 2025

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IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): a small animal acute myocardial infarction randomized-controlled multicenter study on the effect of ischemic preconditioning.
Sauri Hernandez-Resendiz, Reinis Vilskersts, David Aluja, Ioanna Andreadou, Péter Bencsik, Javier Inserte

Basic Res Cardiol· April 2025

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Efficacy of a cysteine protease inhibitor compared with enalapril in murine heart failure models.
David Aluja, Sara Delgado-Tomás, Jose A Barrabés, Elisabet Miró-Casas, Marisol Ruiz-Meana, Javier Inserte

iScience· October 2024

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Connexin 43 modulates reverse electron transfer in cardiac mitochondria from inducible knock-out Cx43 mice by altering the coenzyme Q pool.
Marta Consegal, Elisabet Miró-Casas, Ignasi Barba, Marisol Ruiz-Meana, Javier Inserte

Basic Res Cardiol· August 2024

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Long-Term Protective Effects of Succinate Dehydrogenase Inhibition during Reperfusion with Malonate on Post-Infarction Left Ventricular Scar and Remodeling in Mice.
Laura Valls-Lacalle, Marta Consegal, Freddy G Ganse, Laia Yáñez-Bisbe, Javier Pastor, Javier Inserte

Int J Mol Sci· April 2024

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TRPV4 Channels Promote Pathological, but Not Physiological, Cardiac Remodeling through the Activation of Calcineurin/NFAT and TRPC6.
Laia Yáñez-Bisbe, Mar Moya, Antonio Rodríguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte

Int J Mol Sci· January 2024

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Spontaneous reperfusion enhances succinate concentration in peripheral blood from stemi patients but its levels does not correlate with myocardial infarct size or area at risk.
Marta Consegal, Ignasi Barba, Bruno García Del Blanco, Imanol Otaegui, José F Rodríguez-Palomares, Javier Inserte

Sci Rep· April 2023

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Cardiac fibroblasts display endurance to ischemia, high ROS control and elevated respiration regulated by the JAK2/STAT pathway.
Aida Beà, Juan García Valero, Andrea Irazoki, Carlos Lana, Guillermo López-Lluch, Javier Inserte

FEBS J· May 2022

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Calpains as Potential Therapeutic Targets for Myocardial Hypertrophy.
David Aluja, Sara Delgado-Tomás, Marisol Ruiz-Meana, José A Barrabés, Javier Inserte

Int J Mol Sci· April 2022

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Defective dimerization of FoF1-ATP synthase secondary to glycation favors mitochondrial energy deficiency in cardiomyocytes during aging.
Diana Bou-Teen, Celia Fernandez-Sanz, Elisabet Miro-Casas, Zuzana Nichtova, Elena Bonzon-Kulichenko, Javier Inserte

Aging Cell· March 2022

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Aging Impairs Reverse Remodeling and Recovery of Ventricular Function after Isoproterenol-Induced Cardiomyopathy.
Laia Yáñez-Bisbe, Anna Garcia-Elias, Marta Tajes, Isaac Almendros, Antonio Rodríguez-Sinovas, Javier Inserte

Int J Mol Sci· December 2021

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Implications of Iron Deficiency in STEMI Patients and in a Murine Model of Myocardial Infarction.
Javier Inserte, José A Barrabés, David Aluja, Imanol Otaegui, Jordi Bañeras

JACC Basic Transl Sci· July 2021

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Citric Acid Cycle Metabolites Predict Infarct Size in Submitted to Transient Coronary Artery Occlusion and Treated with Succinate Dehydrogenase Inhibitors or Remote Ischemic Perconditioning.
Marta Consegal, Norberto Núñez, Ignasi Barba, Begoña Benito, Marisol Ruiz-Meana, Javier Inserte

Int J Mol Sci· April 2021

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Effect of COMBinAtion therapy with remote ischemic conditioning and exenatide on the Myocardial Infarct size: a two-by-two factorial randomized trial (COMBAT-MI).
Bruno García Del Blanco, Imanol Otaegui, José F Rodríguez-Palomares, Antoni Bayés-Genis, Eduard Fernández-Nofrerías, Javier Inserte

Basic Res Cardiol· January 2021

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Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction.
Laura Alonso-Herranz, Álvaro Sahún-Español, Ana Paredes, Pilar Gonzalo, Polyxeni Gkontra, Javier Inserte

Elife· October 2020

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Connexin 43 Deficiency Is Associated with Reduced Myocardial Scar Size and Attenuated TGFβ1 Signaling after Transient Coronary Occlusion in Conditional Knock-Out Mice.
Laura Valls-Lacalle, Marta Consegal, Marisol Ruiz-Meana, Begoña Benito, Javier Inserte

Biomolecules· April 2020

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Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion.
Petronila Penela, Javier Inserte, Paula Ramos, Antonio Rodriguez-Sinovas, David Garcia-Dorado

EBioMedicine· October 2019

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High-fat diet improves tolerance to myocardial ischemia by delaying normalization of intracellular PH at reperfusion.
Javier Inserte, David Aluja, Ignasi Barba, Marisol Ruiz-Meana, Elisabet Miró

J Mol Cell Cardiol· August 2019

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Calpains mediate isoproterenol-induced hypertrophy through modulation of GRK2.
David Aluja, Javier Inserte, Petronila Penela, Paula Ramos, Catalina Ribas

Basic Res Cardiol· March 2019

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