Publications by authors named "Jay Chung"

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Adipose microsomal triglyceride transfer protein deficiency protects against hepatic steatosis by upregulating PPARα activity.
Sujith Rajan, Michael Verano, Thomas Palaia, Chandana Prakashmurthy, Jay Chung

JHEP Rep· December 2025

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Selective inhibition of long isoforms of phosphodiesterase 4D mitigates liver fibrosis in mouse models.
Jeonghan Kim, Heeeun Yoon, Seoung Chan Joe, Antoine Smith, Jinsung Park, Jay H Chung

J Clin Invest· November 2025

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How do we utilize information technology to reduce telephone calls in the clinical laboratory?
Samuel I McCash, Deborah Korenstein, Nina Raoof, Rachel Davis Dunn, Jonathan Gurman, Jay You Chung

Am J Clin Pathol· October 2025

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Endonuclease G promotes hepatic mitochondrial respiration by selectively increasing mitochondrial tRNA production.
Xihui Xu, Rozhin Penjweini, Lóránt Székvölgyi, Zsolt Karányi, Anne-Marie Heckel, Jay H Chung

Proc Natl Acad Sci U S A· January 2025

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The role of the mitochondrial protein VDAC1 in inflammatory bowel disease: a potential therapeutic target.
Ankit Verma, Srinivas Pittala, Belal Alhozeel, Anna Shteinfer-Kuzmine, Ehud Ohana, Jay H Chung

Mol Ther· April 2024

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Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes.
Christine Deisl, Jay H Chung, Donald W Hilgemann

J Gen Physiol· October 2023

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Correction: Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes.
Christine Deisl, Jay H Chung, Donald W Hilgemann

J Gen Physiol· October 2023

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Molecular mechanisms of mitochondrial DNA release and activation of the cGAS-STING pathway.
Jeonghan Kim, Ho-Shik Kim, Jay H Chung

Exp Mol Med· March 2023

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Pore-like diffusion barriers in murine cardiac myocytes.
Christine Deisl, Jay A Chung, Donald W Hilgemann

bioRxiv· January 2023

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Computational Modeling and Imaging of the Intracellular Oxygen Gradient.
Andrew J H Sedlack, Rozhin Penjweini, Katie A Link, Alexandra Brown, Jeonghan Kim, Jay H Chung

Int J Mol Sci· October 2022

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The role of the mitochondrial protein VDAC1 in inflammatory bowel disease: a potential therapeutic target.
Ankit Verma, Srinivas Pittala, Belal Alhozeel, Anna Shteinfer-Kuzmine, Ehud Ohana, Jay H Chung

Mol Ther· February 2022

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Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis.
Sung-Jun Park, Faiyaz Ahmad, Robert J Bahde, Andrew Philp, Jeonghan Kim, Jay H Chung

PLoS One· November 2021

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Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease.
Laxminath Tumburu, Shohini Ghosh-Choudhary, Fayaz T Seifuddin, Emilia A Barbu, Simon Yang, Jay H Chung

Blood· June 2021

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Electrospun Microfibers Modulate Intracellular Amino Acids in Liver Cells via Integrin β1.
Tianjiao Huang, John A Terrell, Jay H Chung, Chengpeng Chen

Bioengineering (Basel)· June 2021

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3D-Printed, Modular, and Parallelized Microfluidic System with Customizable Scaffold Integration to Investigate the Roles of Basement Membrane Topography on Endothelial Cells.
Curtis G Jones, Tianjiao Huang, Jay H Chung, Chengpeng Chen

ACS Biomater Sci Eng· April 2021

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Inhibition of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) stimulates osteoblastogenesis by potentiating bone morphogenetic protein 2 (BMP2) responses.
Theresa Farhat, Amel Dudakovic, Jay H Chung, Andre J van Wijnen, René St-Arnaud

J Cell Physiol· February 2021

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Microfibrous Extracellular Matrix Changes the Liver Hepatocyte Energy Metabolism via Integrins.
Tianjiao Huang, Curtis G Jones, Jay H Chung, Chengpeng Chen

ACS Biomater Sci Eng· October 2020

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VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.
Jeonghan Kim, Rajeev Gupta, Luz P Blanco, Shutong Yang, Anna Shteinfer-Kuzmine, Jay H Chung

Science· December 2019

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Early effects of roflumilast on insulin sensitivity in adults with prediabetes and overweight/obesity involve age-associated fat mass loss - results of an exploratory study.
Ijeoma M Muo, Sandra D MacDonald, Ritu Madan, Sung-Jun Park, Ahmed M Gharib, Jay H Chung

Diabetes Metab Syndr Obes· May 2019

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Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function.
Ijeoma M Muo, Sung-Jun Park, Antoine Smith, Danielle A Springer, Michele D Allen, Jay H Chung

Biochem Biophys Res Commun· December 2018

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Intracellular oxygen mapping using a myoglobin-mCherry probe with fluorescence lifetime imaging.
Rozhin Penjweini, Alessio Andreoni, Tilman Rosales, Jeonghan Kim, Michael D Brenner, Jay H Chung

J Biomed Opt· October 2018

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The role of DNA-PK in aging and energy metabolism.
Jay H Chung

FEBS J· June 2018

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DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging.
Sung-Jun Park, Oksana Gavrilova, Alexandra L Brown, Jamie E Soto, Shannon Bremner, Jay H Chung

Cell Metab· August 2017

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DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging.
Sung-Jun Park, Oksana Gavrilova, Alexandra L Brown, Jamie E Soto, Shannon Bremner, Jay H Chung

Cell Metab· May 2017

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Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins.
Hyeog Kang, Shinichi Oka, Duck-Yeon Lee, Junhong Park, Angel M Aponte, Jay H Chung

Nat Commun· May 2017

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