Publications by authors named "Jay Fine"

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EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumors.
Oksana A Sergeeva, Guixian Jin, Mohosin Sarkar, Jennifer Zeiger, Sonali Dhindwal, Jay S Fine

Proc Natl Acad Sci U S A· November 2025

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Programmed Cell Death-1 (PD-1) anchoring to the GPI-linked co-receptor CD48 reveals a novel mechanism to modulate PD-1-dependent inhibition of human T cells.
Della White, Alexandra Cote-Martin, Marina Bleck, Nicole Garaffa, Abdulsalam Shaaban, Jay S Fine

Mol Immunol· April 2023

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IL-36 receptor agonist and antagonist imbalance drives neutrophilic inflammation in COPD.
Jonathan R Baker, Peter S Fenwick, Carolin K Koss, Harriet B Owles, Sarah L Elkin, Jay Fine

JCI Insight· August 2022

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Corrigendum to "Bleomycin induced lung fibrosis increases work of breathing in the mouse" [Pulm. Pharmacol.Therapeut. 25 (2012) 281-285].
Jonathan E Phillips, Ruoqi Peng, Lisa Burns, Paul Harris, Rosario Garrido, Jay S Fine

Pulm Pharmacol Ther· June 2022

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The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease.
Joerg Ermann, Mederbek Matmusaev, Emma K Haley, Clemens Braun, Felix Jost, Jay S Fine

Am J Physiol Gastrointest Liver Physiol· November 2021

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Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.
Garrett J Patrick, Haiyun Liu, Martin P Alphonse, Dustin A Dikeman, Christine Youn, Jay S Fine

J Clin Invest· March 2021

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BTK inhibition modulates multiple immune cell populations involved in the pathogenesis of immune mediated nephritis.
Samantha A Chalmers, Sayra J Garcia, Deborah Webb, Leal Herlitz, Jay Fine

Clin Immunol· February 2021

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IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice.
Carolin K Koss, Christian T Wohnhaas, Jonathan R Baker, Cornelia Tilp, Michèl Przibilla, Jay Fine

Commun Biol· February 2021

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Phoenix from the flames: Rediscovering the role of the CD40-CD40L pathway in systemic lupus erythematosus and lupus nephritis.
Meera Ramanujam, Jürgen Steffgen, Sudha Visvanathan, Chandra Mohan, Jay S Fine

Autoimmun Rev· November 2020

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Dysregulation of club cell biology in idiopathic pulmonary fibrosis.
Wu-Lin Zuo, Mahboubeh R Rostami, Michelle LeBlanc, Robert J Kaner, Sarah L O'Beirne, Jay S Fine

PLoS One· October 2020

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Cell-specific expression of lung disease risk-related genes in the human small airway epithelium.
Wu-Lin Zuo, Mahboubeh R Rostami, Shushila A Shenoy, Michelle G LeBlanc, Jacqueline Salit, Jay S Fine

Respir Res· July 2020

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Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.
Jerome C Martin, Christie Chang, Gilles Boschetti, Ryan Ungaro, Mamta Giri, Jay S Fine

Cell· September 2019

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Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity.
Guoqing Wang, Howard H Lou, Jacqueline Salit, Philip L Leopold, Sharon Driscoll, Jay S Fine

Respir Res· August 2019

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Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab.
Sudha Visvanathan, Patrick Baum, Richard Vinisko, Ramona Schmid, Mary Flack, Jay S Fine

J Allergy Clin Immunol· June 2019

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Effects of BI 655064, an antagonistic anti-CD40 antibody, on clinical and biomarker variables in patients with active rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase IIa study.
Sudha Visvanathan, Stefan Daniluk, Rafał Ptaszyński, Ulf Müller-Ladner, Meera Ramanujam, Jay S Fine

Ann Rheum Dis· June 2019

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Ambient Pollution-related Reprogramming of the Human Small Airway Epithelial Transcriptome.
Sarah L O'Beirne, Sushila A Shenoy, Jacqueline Salit, Yael Strulovici-Barel, Robert J Kaner, Jay S Fine

Am J Respir Crit Care Med· December 2018

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BTK inhibition ameliorates kidney disease in spontaneous lupus nephritis.
Samantha A Chalmers, Elizabeth Glynn, Sayra J Garcia, Mark Panzenbeck, Josephine Pelletier, Jay S Fine

Clin Immunol· December 2018

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Selective IL-23 Inhibition by Risankizumab Modulates the Molecular Profile in the Colon and Ileum of Patients With Active Crohn's Disease: Results From a Randomised Phase II Biopsy Sub-study.
Sudha Visvanathan, Patrick Baum, Azucena Salas, Richard Vinisko, Ramona Schmid, Jay S Fine

J Crohns Colitis· November 2018

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Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus.
Samantha A Chalmers, Jing Wen, Jessica Doerner, Ariel Stock, Carla M Cuda, Jay S Fine

Arthritis Res Ther· January 2018

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Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies.
Rajkumar Ganesan, Ernest L Raymond, Detlev Mennerich, Joseph R Woska, Gary Caviness, Jay S Fine

MAbs· October 2017

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Persistence of circulating endothelial microparticles in COPD despite smoking cessation.
Yael Strulovici-Barel, Michelle R Staudt, Anja Krause, Cynthia Gordon, Ann E Tilley, Jay S Fine

Thorax· December 2016

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Therapeutic Blockade of Immune Complex-Mediated Glomerulonephritis by Highly Selective Inhibition of Bruton's Tyrosine Kinase.
Samantha A Chalmers, Jessica Doerner, Todd Bosanac, Sara Khalil, Dustin Smith, Jay S Fine

Sci Rep· May 2016

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Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.
Guoqing Wang, Rui Wang, Yael Strulovici-Barel, Jacqueline Salit, Michelle R Staudt, Jay S Fine

PLoS One· January 2016

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Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants.
Linda M Hartkamp, Jay S Fine, Inge E van Es, Man Wai Tang, Michael Smith

Ann Rheum Dis· August 2015

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Intraflagellar transport gene expression associated with short cilia in smoking and COPD.
Justina Hessel, Jonna Heldrich, Jennifer Fuller, Michelle R Staudt, Sharon Radisch, Jay Fine

PLoS One· December 2014

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