Publications by authors named "Jay Hinton"

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Transcriptomic analysis of serotype 1 reveals serotype-specific gene regulation.
Pisut Pongchaikul, Karsten Hokamp, Morten Kjos, Chrispin Chaguza, Teerawit Audshasai, Jay C D Hinton

Microb Genom· December 2025

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Molecular basis of the biogenesis of a protein organelle for ethanolamine utilization.
Mengru Yang, Oluwatobi Adegbite, Ping Chang, Jin Cheng, Yue Wang, Jay C D Hinton

Sci Adv· October 2025

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Global diversity and evolution of Salmonella enterica serovar Panama: a genomic epidemiology study.
Caisey V Pulford, Blanca M Perez-Sepulveda, Danielle J Ingle, Rebecca J Bengtsson, Rebecca J Bennett, Jay C D Hinton

Lancet Microbe· September 2025

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Diversity of Salmonella enterica isolates from urban river and sewage water in Blantyre, Malawi.
Jonathan Rigby, Catherine N Wilson, Allan Zuza, Yohane Diness, Charity Mkwanda, Jay C D Hinton

PLoS Negl Trop Dis· September 2025

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African serovar Typhimurium ST313 isolates prevent reactive oxygen species production by human neutrophils via elevated PgtE expression.
Annica R Stull-Lane, Lizbeth Camacho, Amber E R Van Hecke, Blanca Perez-Sepulveda, Eli J Bejarano, Jay C D Hinton

mBio· August 2025

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Corrigendum to "Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection" [Mucosal. Immun. 17 (2024) 1242-1255].
Amanpreet Singh Chawla, Maud Vandereyken, Maykel Arias, Llipsy Santiago, Dina Dikovskaya, Jay C D Hinton

Mucosal Immunol· August 2025

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Enhancing infectious intestinal disease diagnosis through metagenomic and metatranscriptomic sequencing of 1000 human diarrhoeal samples.
Edward Cunningham-Oakes, Blanca M Perez-Sepulveda, Yan Li, Jay C D Hinton, Charlotte A Nelson

Genome Med· May 2025

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Profiling Salmonella transcriptional dynamics during macrophage infection using a comprehensive reporter library.
Taylor H Nguyen, Benjamin X Wang, Oscar R Diaz, Manohary Rajendram, Joy A McKenna, Jay C D Hinton

Nat Microbiol· April 2025

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Microbe Profile: Typhimurium: the master of the art of adaptation.
Blanca M Perez-Sepulveda, Jay C D Hinton

Microbiology (Reading)· January 2025

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Potential links between human bloodstream infection by Salmonella enterica serovar Typhimurium and international transmission to Colombia.
Yan Li, Caisey V Pulford, Paula Díaz, Blanca M Perez-Sepulveda, Carolina Duarte, Jay C D Hinton

PLoS Negl Trop Dis· January 2025

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Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence.
Sam C Went, David M Picton, Richard D Morgan, Andrew Nelson, Aisling Brady, Jay C D Hinton

Nat Commun· August 2024

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Modulation of virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex.
Xiu-Jun Yu, Haixia Xie, Yan Li, Mei Liu, Ruhong Hou, Jay C D Hinton

mBio· July 2024

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High-throughput fitness experiments reveal specific vulnerabilities of human-adapted Salmonella during stress and infection.
Benjamin X Wang, Dmitry Leshchiner, Lijuan Luo, Miles Tuncel, Karsten Hokamp, Jay C D Hinton

Nat Genet· June 2024

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Succinate utilisation by Salmonella is inhibited by multiple regulatory systems.
Nicolas Wenner, Xiaojun Zhu, Will P M Rowe, Kristian Händler, Jay C D Hinton

PLoS Genet· March 2024

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serovar Typhimurium ST313 sublineage 2.2 has emerged in Malawi with a characteristic gene expression signature and a fitness advantage.
Benjamin Kumwenda, Rocío Canals, Alexander V Predeus, Xiaojun Zhu, Carsten Kröger, Jay C D Hinton

Microlife· March 2024

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Protocol for the challenge non-typhoidal (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK.
Christopher Smith, Emma Smith, Anna Rydlova, Robert Varro, Jay C D Hinton

BMJ Open· January 2024

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Diverse Durham collection phages demonstrate complex BREX defense responses.
Abigail Kelly, Sam C Went, Giuseppina Mariano, Liam P Shaw, David M Picton, Jay C D Hinton

Appl Environ Microbiol· September 2023

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The Challenge Non-Typhoidal (CHANTS) Consortium: Development of a non-typhoidal controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK.
Christopher Smith, Emma Smith, Christopher Chiu, Jay Hinton, Blanca Perez Sepulveda

Wellcome Open Res· September 2023

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Class 1 integrons in clinical and swine industry isolates of Typhimurium from Colombia, dating 1997 to 2017.
Nancy Yaneth Flórez-Delgado, Elizabeth Noelia Ubillus, Blanca Perez-Sepulveda, Eyda Lizeth Ospina-Ríos, Ana Karina Carrascal-Camacho, Jay C D Hinton

J Med Microbiol· June 2023

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Genome-wide fitness analysis identifies genes required for growth and macrophage infection by African and global epidemic pathovariants of Enteritidis.
Wai Yee Fong, Rocío Canals, Alexander V Predeus, Blanca Perez-Sepulveda, Nicolas Wenner, Jay C D Hinton

Microb Genom· May 2023

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Multiplex PCR Assay for Clade Typing of Salmonella enterica Serovar Enteritidis.
Sarah Gallichan, Blanca M Perez-Sepulveda, Nicholas A Feasey, Jay C D Hinton, Juno Thomas

Microbiol Spectr· December 2022

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Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission.
Leonard Koolman, Reenesh Prakash, Yohane Diness, Chisomo Msefula, Tonney S Nyirenda, Jay C D Hinton

PLoS Negl Trop Dis· December 2022

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A widespread family of WYL-domain transcriptional regulators co-localizes with diverse phage defence systems and islands.
David M Picton, Joshua D Harling-Lee, Samuel J Duffner, Sam C Went, Richard D Morgan, Jay C D Hinton

Nucleic Acids Res· May 2022

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Biogenesis of a bacterial metabolosome for propanediol utilization.
Mengru Yang, Nicolas Wenner, Gregory F Dykes, Yan Li, Xiaojun Zhu, Jay C D Hinton

Nat Commun· May 2022

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Greater Breast Support Alters Trunk and Knee Joint Biomechanics Commonly Associated With Anterior Cruciate Ligament Injury.
Hailey B Fong, Alexis K Nelson, Julie E Storey, Jay Hinton, Melissa Puppa

Front Sports Act Living· May 2022

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