Publications by authors named "Jay Patrick"

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Impact of patisiran on polyneuropathy of hereditary transthyretin amyloidosis in patients with a V122I or T60A variant: a phase IV multicenter study.
Yessar Hussain, Saurabh Malhotra, Brett W Sperry, Francy Shu, Karthikeyan Ananthasubramaniam, Patrick Y Jay

Ann Med· December 2025

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Effects of vutrisiran on cardiac structure and function in patients with transthyretin amyloidosis with cardiomyopathy: secondary outcomes of the HELIOS-B trial.
Karola S Jering, Marianna Fontana, Olivier Lairez, Simone Longhi, Olga Azevedo, Patrick Y Jay

Nat Med· October 2025

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Benefits of Patisiran on Functional Capacity in ATTR Cardiac Amyloidosis: Post Hoc Analysis of APOLLO-B.
John L Berk, Olivier Lairez, Pedro Schwartzmann, Shaun Bender, Matthew T White, Patrick Y Jay

JACC Adv· August 2025

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Effects of Vutrisiran on Cardiac Function and Outcomes in Patients With Transthyretin Amyloidosis With Cardiomyopathy.
Karola S Jering, Marianna Fontana, Hicham Skali, Bernard E Bulwer, Narayana Prasad, Patrick Y Jay

J Am Coll Cardiol· August 2025

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Impact of Vutrisiran on Cardiac Biomarkers in Patients With Transthyretin Amyloidosis With Cardiomyopathy From HELIOS-B.
Mathew S Maurer, John L Berk, Thibaud Damy, Farooq H Sheikh, José González-Costello, Patrick Y Jay

J Am Coll Cardiol· August 2025

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Five-Year Results With Patisiran for Hereditary Transthyretin Amyloidosis With Polyneuropathy: A Randomized Clinical Trial With Open-Label Extension.
David Adams, Jonas Wixner, Michael Polydefkis, John L Berk, Isabel M Conceição, Patrick Y Jay

JAMA Neurol· March 2025

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Patisiran Treatment in the Brazilian Subpopulation of the Phase 3 APOLLO-B Study in Transthyretin Amyloidosis with Cardiomyopathy: Post Hoc Analysis.
Claudio Tinoco Mesquita, Pedro Schwartzmann, Edileide Barros Correia, Marcus V Simões, Andreia Biolo, Patrick Y Jay

Arq Bras Cardiol· March 2025

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Outpatient Worsening Heart Failure in Patients With Transthyretin Amyloidosis With Cardiomyopathy in the HELIOS-B Trial.
Marianna Fontana, Mathew S Maurer, Julian D Gillmore, Shaun Bender, Emre Aldinc, Patrick Y Jay

J Am Coll Cardiol· February 2025

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Worsening of Heart Failure in Outpatients With Transthyretin Amyloidosis and Cardiomyopathy in the APOLLO-B Trial.
Marianna Fontana, Mathew S Maurer, Julian D Gillmore, Shaun Bender, Patrick Y Jay

J Am Coll Cardiol· February 2025

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Molecular Pathways and Animal Models of Atrial Septal Defect.
Rachel A Magnan, Lillian Kang, Karl R Degenhardt, Robert H Anderson, Patrick Y Jay

Adv Exp Med Biol· June 2024

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Heterogeneous cardiac sympathetic innervation gradients promote arrhythmogenesis in murine dilated cardiomyopathy.
Al-Hassan J Dajani, Michael B Liu, Michael A Olaopa, Lucian Cao, Carla Valenzuela-Ripoll, Patrick Y Jay

JCI Insight· November 2023

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Pharmacokinetics and Pharmacodynamics of Patisiran in Patients with hATTR Amyloidosis and with Polyneuropathy After Liver Transplantation.
Prajakta Badri, Bahru Habtemariam, Megan Melch, Valerie A Clausen, Seth Arum, Patrick Y Jay

Clin Pharmacokinet· October 2023

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Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis.
Mathew S Maurer, Parag Kale, Marianna Fontana, John L Berk, Martha Grogan, Patrick Y Jay

N Engl J Med· October 2023

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Repurposing Normal Chromosomal Microarray Data to Harbor Genetic Insights into Congenital Heart Disease.
Nephi A Walton, Hoang H Nguyen, Sara S Procknow, Darren Johnson, Alexander Anzelmi, Patrick Y Jay

Biology (Basel)· September 2023

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Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profiling.
Sachin Sharma, Russell Littman, John D Tompkins, Douglas Arneson, Jaime Contreras, Patrick Y Jay

Elife· May 2023

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Tiered Sympathetic Control of Cardiac Function Revealed by Viral Tracing and Single Cell Transcriptome Profiling.
Sachin Sharma, Russell Littman, John Tompkins, Douglas Arneson, Jaime Contreras, Patrick Y Jay

bioRxiv· January 2023

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Congenital Aneurysm of the Muscular Interventricular Septum Associated With Bifascicular Block.
Hoang H Nguyen, Patrick Y Jay

Cureus· October 2022

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Patisiran treatment in patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy after liver transplantation.
Hartmut H Schmidt, Jonas Wixner, Violaine Planté-Bordeneuve, Francisco Muñoz-Beamud, Laura Lladó, Patrick Y Jay

Am J Transplant· June 2022

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The Genetic Architecture of a Congenital Heart Defect Is Related to Its Fitness Cost.
Ehiole Akhirome, Suk D Regmi, Rachel A Magnan, Nelson Ugwu, Yidan Qin, Patrick Y Jay

Genes (Basel)· August 2021

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Dichotomous roles of in the establishment of atrioventricular conduction pathways in the human heart.
Hoang H Nguyen, Dorothy K Grange, Mark C Johnson, George F Van Hare, Patrick Y Jay

HeartRhythm Case Rep· February 2019

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Molecules and microbes and cells, Oh My! What mothers give to us besides genes.
Patrick Y Jay, Michiko Watanabe

Birth Defects Res· December 2018

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Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia.
Monique R Heitmeier, Maria A Payne, Carla Weinheimer, Attila Kovacs, Richard C Hresko, Patrick Y Jay

Sci Rep· April 2018

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Myocardial Induction of Type 3 Deiodinase in Dilated Cardiomyopathy.
Ari J Wassner, Rebecca H Jugo, David M Dorfman, Robert F Padera, Michelle A Maynard, Patrick Y Jay

Thyroid· May 2017

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The Complex Genetic Basis of Congenital Heart Defects.
Ehiole Akhirome, Nephi A Walton, Julie M Nogee, Patrick Y Jay

Circ J· April 2017

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Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart.
Adam A Panzer, Suk D Regmi, DePorres Cormier, Megan T Danzo, Iuan-Bor D Chen, Patrick Y Jay

Sci Rep· April 2017

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