Publications by authors named "Michael Polydefkis"

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Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis.
Simina Ticau, Gautham V Sridharan, Shira Tsour, William L Cantley, Amy Chan, Jason A Gilbert, David Erbe, Emre Aldinc, Mary M Reilly, David Adams

Neurology· January 2021

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A comparison of single versus combination mechanism treatment for transthyretin amyloid cardiomyopathy.
Vrinda Gupta, Lisa R Yanek, Bairavi Shankar, Artrish Jefferson, Daniel Tsottles, Michael Polydefkis

Amyloid· October 2025

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Neuropathy impairment and nutritional status with eplontersen in patients with hereditary transthyretin-mediated amyloidosis.
Jonas Wixner, Isabel Conceição, John L Berk, David Adams, Michael J Polydefkis

Amyloid· October 2025

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High rate of false negative Tc-pyrophosphate scintigraphy scans in patients with Leu58His transthyretin amyloid cardiomyopathy.
Muhammed A Rahim, Vivek Jani, Vrinda Gupta, Serena Zampino, Daniel Tsottles, Michael Polydefkis

Amyloid· September 2025

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Effects of eplontersen on symptoms of autonomic neuropathy in hereditary transthyretin-mediated amyloidosis: secondary analysis from the NEURO-TTRansform trial.
Jonas Wixner, John L Berk, David Adams, Michael Polydefkis, Isabel Conceição

Amyloid· March 2025

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Five-Year Results With Patisiran for Hereditary Transthyretin Amyloidosis With Polyneuropathy: A Randomized Clinical Trial With Open-Label Extension.
David Adams, Jonas Wixner, Michael Polydefkis, John L Berk, Isabel M Conceição

JAMA Neurol· March 2025

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Symptoms of Hereditary Transthyretin Amyloidosis: The Patient and Physician Perspective.
Michael Lane, Michael Polydefkis

Neurol Ther· December 2024

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Vitamin D levels do not correlate with severity of idiopathic peripheral neuropathy.
Alexander H Morrison, Maya Hoke, Simone Thomas, Vinay Chaudhry, Michael Polydefkis

J Peripher Nerv Syst· December 2024

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Joint Hypermobility, Autonomic Dysfunction, Gastrointestinal Dysfunction, and Autoimmune Markers: Clinical Associations and Response to Intravenous Immunoglobulin Therapy.
Pankaj J Pasricha, Megan McKnight, Luisa Villatoro, Guillermo Barahona, Jeffrey Brinker, Michael Polydefkis

Am J Gastroenterol· November 2024

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A phase 2a study investigating the effects of ritlecitinib on brainstem auditory evoked potentials and intraepidermal nerve fiber histology in adults with alopecia areata.
Samira Anderson, Guido Cavaletti, Linda J Hood, Michael Polydefkis, David N Herrmann

Pharmacol Res Perspect· August 2024

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Pain Hypersensitivity in SLURP1 and SLURP2 Knock-out Mouse Models of Hereditary Palmoplantar Keratoderma.
Rachel L Weinberg, Suyeon Kim, Zixuan Pang, Sandy Awad, Tyger Hanback, Michael J Polydefkis

J Neurosci· July 2024

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Race and Socioeconomic Status Impact Diagnosis and Clinical Outcomes in Transthyretin Cardiac Amyloidosis.
Bairavi Shankar, Lisa Yanek, Artrish Jefferson, Vivek Jani, Emily Brown, Michael Polydefkis

JACC CardioOncol· June 2024

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Coexistence of Light Chain and Transthyretin Cardiac Amyloidosis.
Abhishek Gami, John Woller, Paul Scheel, Syed Abbas Ali, Carol Ann Huff, Michael Polydefkis

JACC Case Rep· April 2024

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Treatment response and neurofilament light chain levels with long-term patisiran in hereditary transthyretin-mediated amyloidosis with polyneuropathy: 24-month results of an open-label extension study.
Simina Ticau, Emre Aldinc, Michael Polydefkis, David Adams, Teresa Coelho

Amyloid· March 2024

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Diagnosis and treatment of hereditary transthyretin amyloidosis with polyneuropathy in the United States: Recommendations from a panel of experts.
Chafic Karam, Michelle L Mauermann, Alejandra Gonzalez-Duarte, Michelle C Kaku, Senda Ajroud-Driss, Michael Polydefkis

Muscle Nerve· March 2024

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Neurofilament Light Chains in Systemic Amyloidosis: A Systematic Review.
Milou Berends, Hans L A Nienhuis, David Adams, Chafic Karam, Marco Luigetti, Michael Polydefkis

Int J Mol Sci· March 2024

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Hereditary transthyretin amyloid neuropathies: advances in pathophysiology, biomarkers, and treatment.
David Adams, Yoshiki Sekijima, Isabel Conceição, Marcia Waddington-Cruz, Michael Polydefkis

Lancet Neurol· November 2023

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Phenotypes Associated With the Val122Ile, Leu58His, and Late-Onset Val30Met Variants in Patients With Hereditary Transthyretin Amyloidosis.
Serena Zampino, Farooq H Sheikh, Joban Vaishnav, Daniel Judge, Baohan Pan, Michael Polydefkis

Neurology· May 2023

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Efficacy and safety of vutrisiran for patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy: a randomized clinical trial.
David Adams, Ivailo L Tournev, Mark S Taylor, Teresa Coelho, Violaine Planté-Bordeneuve, Michael Polydefkis

Amyloid· March 2023

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Long-term efficacy and safety of inotersen for hereditary transthyretin amyloidosis: NEURO-TTR open-label extension 3-year update.
Thomas H Brannagan, Teresa Coelho, Annabel K Wang, Michael J Polydefkis, Peter J Dyck

J Neurol· December 2022

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Large Pleural Effusion: A Pitfall in the Quantitation of 99m Tc-PYP Imaging for ATTR Cardiac Amyloidosis.
Wajahat Khatri, Michael Polydefkis, Joban Vaishnav, Elie Saad, Lilja B Solnes

Clin Nucl Med· September 2022

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Mycobacterium leprae induces Schwann cell proliferation and migration in a denervated milieu following intracutaneous excision axotomy in nine-banded armadillos.
Gigi J Ebenezer, Maria T Pena, Amrita S Daniel, Richard W Truman, Linda Adams, Michael Polydefkis

Exp Neurol· June 2022

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Neuropathic symptoms with SARS-CoV-2 vaccination.
Farinaz Safavi, Lindsey Gustafson, Brian Walitt, Tanya Lehky, Sara Dehbashi, Michael Polydefkis

medRxiv· May 2022

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Correction to: Peripheral Neuropathy: No Longer the Land of Therapeutic Nihilism.
Michael Polydefkis, Charlotte J Sumner

Neurotherapeutics· March 2022

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Expert opinion on monitoring symptomatic hereditary transthyretin-mediated amyloidosis and assessment of disease progression.
David Adams, Vincent Algalarrondo, Michael Polydefkis, Nitasha Sarswat, Michel S Slama

Orphanet J Rare Dis· October 2021

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Peripheral Neuropathy: No Longer the Land of Therapeutic Nihilism.
Michael Polydefkis, Charlotte J Sumner

Neurotherapeutics· October 2021

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