Publications by authors named "Jay Rappaport"

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Persistent Activation of Monocytes/Macrophages and Cell Senescence in SIV-Infected Macaques on ART.
Yilin Chen, Xiaofeng Ding, Sonalika Ray, Siva Thirugnanam, Robert Blair, Jay Rappaport

bioRxiv· November 2025

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Plasma circulating extracellular vesicles reveal dysregulation of synaptic signaling in SHIV-infected rhesus macaque.
Partha K Chandra, Manesh Kumar Panner Selvam, Tasniya N Zulfiquar, Ibolya Rutkai-Green, Suresh C Sikka, Jay Rappaport

Cell Commun Signal· October 2025

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Upregulation of inflammatory genes and pathways links obesity to severe COVID-19.
Joshua Currey, Calder Ellsworth, Mst Shamima Khatun, Chenxiao Wang, Zheng Chen, Jay Rappaport

Biochim Biophys Acta Mol Basis Dis· October 2024

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HIV Protein Nef Induces Cardiomyopathy Through Induction of Bcl2 and p21.
Olena Kondrachuk, Pierce Ciccone, Nicole Ford, Kim Hong, Yuka Kimura, Jay Rappaport

Int J Mol Sci· October 2024

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Non-human primate model of long-COVID identifies immune associates of hyperglycemia.
Clovis S Palmer, Chrysostomos Perdios, Mohamed Abdel-Mohsen, Joseph Mudd, Prasun K Datta, Jay Rappaport

Nat Commun· August 2024

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The Association between IL-1β and IL-18 Levels, Gut Barrier Disruption, and Monocyte Activation during Chronic Simian Immunodeficiency Virus Infection and Long-Term Suppressive Antiretroviral Therapy.
Siva Thirugnanam, Chenxiao Wang, Chen Zheng, Brooke F Grasperge, Prasun K Datta, Jay Rappaport

Int J Mol Sci· August 2024

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The Impact of SIV-Induced Immunodeficiency on SARS-CoV-2 Disease, Viral Dynamics, and Antiviral Immune Response in a Nonhuman Primate Model of Coinfection.
Alexandra Melton, Lori A Rowe, Toni Penney, Clara Krzykwa, Kelly Goff, Jay Rappaport

Viruses· July 2024

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High IL-1β and IL-18 Levels Associate with Gut Barrier Disruption and Monocyte Activation During Chronic SIV Infection with Long-Term Suppressive Antiretroviral Therapy.
Siva Thirugnanam, Chenxiao Wang, Chen Zheng, Brooke F Grasperge, Prasun K Datta, Jay Rappaport

bioRxiv· June 2024

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COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes.
Chenxiao Wang, Mst Shamima Khatun, Zhe Zhang, Michaela J Allen, Zheng Chen, Jay Rappaport

Commun Biol· December 2023

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SARS-CoV-2 RNA persists in the central nervous system of non-human primates despite clinical recovery.
Hailong Li, Kristen A McLaurin, Charles F Mactutus, Jay Rappaport, Prasun K Datta

Mol Biomed· November 2023

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The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection.
Alexandra Melton, Lori A Rowe, Toni Penney, Clara Krzykwa, Kelly Goff, Jay Rappaport

bioRxiv· November 2023

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Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161CD8 T Cells in SIV-Infected Rhesus Macaques.
Siva Thirugnanam, Edith M Walker, Faith Schiro, Pyone P Aye, Jay Rappaport

Viruses· September 2023

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SARS-CoV-2 RNA Persists in the Central Nervous System of Non-Human Primates Despite Clinical Recovery.
Hailong Li, Kristen A McLaurin, Charles F Mactutus, Jay Rappaport, Prasun K Datta

bioRxiv· August 2023

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SARS-CoV-2 infection dysregulates NAD metabolism.
Amin Izadpanah, Joseph C Mudd, Joe G N Garcia, Sudesh Srivastav, Mohamed Abdel-Mohsen, Jay Rappaport

Front Immunol· July 2023

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SuPAR mediates viral response proteinuria by rapidly changing podocyte function.
Changli Wei, Prasun K Datta, Florian Siegerist, Jing Li, Sudhini Yashwanth, Jay Rappaport

Nat Commun· July 2023

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The Role of Gut Dysbiosis in the Loss of Intestinal Immune Cell Functions and Viral Pathogenesis.
Farzaneh Fakharian, Siva Thirugnanam, David A Welsh, Woong-Ki Kim, Jay Rappaport

Microorganisms· July 2023

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Mid-titer human convalescent plasma administration results in suboptimal prophylaxis against SARS-CoV-2 infection in rhesus macaques.
Brandon J Beddingfield, Nicholas J Maness, Skye Spencer, Jay Rappaport, Pyone Pyone Aye

Front Immunol· February 2023

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Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.
Prabhu S Arunachalam, Yupeng Feng, Usama Ashraf, Mengyun Hu, Alexandra C Walls, Jay Rappaport

Sci Transl Med· August 2022

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eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis.
Alexander N Garcia, Nancy G Casanova, Carrie L Kempf, Tadeo Bermudez, Daniel G Valera, Jay Rappaport

Am J Respir Cell Mol Biol· May 2022

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C57BL/6J Mice Are Not Suitable for Modeling Severe SARS-CoV-2 Beta and Gamma Variant Infection.
Joshua M Currey, Felix Rabito, Nicholas J Maness, Robert V Blair, Jay Rappaport

Viruses· May 2022

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Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates.
Ibolya Rutkai, Meredith G Mayer, Linh M Hellmers, Bo Ning, Zhen Huang, Jay Rappaport

Nat Commun· April 2022

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Epitranscriptomics of SARS-CoV-2 Infection.
Amin Izadpanah, Jay Rappaport, Prasun K Datta

Front Cell Dev Biol· April 2022

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Engineering monoclonal antibodies for COVID-19 prophylaxis.
Amin Izadpanah, Jay Rappaport

Med· March 2022

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Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates.
Stéphane Pillet, Prabhu S Arunachalam, Guadalupe Andreani, Nadia Golden, Jane Fontenot, Jay Rappaport

Cell Mol Immunol· February 2022

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Activation of Immune System May Cause Pathophysiological Changes in the Myocardium of SARS-CoV-2 Infected Monkey Model.
Maryam Yahya Rabbani, Jay Rappaport, Manish Kumar Gupta

Cells· February 2022

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