Publications by authors named "Jayakumar Nair"

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A Phase II Pilot Study of Anti-PD-L1, Durvalumab, and a PARP Inhibitor, Olaparib in Patients With Metastatic Triple-Negative Breast Cancer With or Without Germline BRCA Mutation.
Takeo Fujii, Ashley Cimino-Mathews, Stanley Lipkowitz, Min-Jung Lee, Jayakumar Nair

Cancer Med· December 2025

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The KIF18A Inhibitor ATX020 Induces Mitotic Arrest and DNA Damage in Chromosomally Instable High-Grade Serous Ovarian Cancer Cells.
Jayakumar Nair, Tzu-Ting Huang, Maureen Lynes, Sanjoy Khan, Serena Silver

Cells· November 2025

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Editorial: Community series in the immunosuppressive tumor microenvironment and strategies to revert its immune regulatory milieu for cancer immunotherapy, volume II.
Mazdak Ganjalikhani Hakemi, Nair Jayakumar

Front Immunol· October 2025

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Phase II proof-of-concept study of durvalumab and cediranib with and without olaparib in recurrent ovarian cancer.
Jung-Min Lee, Junya Tabata, Tzu-Ting Huang, Elena Giudice, Kristen Ibanez, Jayakumar Nair

Res Sq· October 2025

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Comparison of conventional and modified carbo-dissection techniques for LIMA harvesting in CABG.
Jayakumar Thanathu Krishnan Nair, Dinesh Kumar Sathanantham, Joseph Kathayanat Thomas

Indian J Thorac Cardiovasc Surg· February 2025

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Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer.
Jayakumar R Nair, Tzu-Ting Huang, Anu Sunkara, Margaret R Pruitt, Kristen R Ibanez

iScience· December 2024

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Echocardiography-Guided Successful Off-Pump Submitral Aneurysm Repair With Coronary Artery Bypass.
Jayakumar Thanathu Krishnan Nair, Manjusha N Pillai, Dinesh Kumar Sathanantham, Noufal Thekkara Basheer

Ann Thorac Surg Short Rep· December 2024

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Poly (ADP-Ribose) Polymerase Inhibitor Olaparib-Resistant -Mutant Ovarian Cancer Cells Demonstrate Differential Sensitivity to PARP Inhibitor Rechallenge.
Chi-Ting Shih, Tzu-Ting Huang, Jayakumar R Nair, Kristen R Ibanez, Jung-Min Lee

Cells· November 2024

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Unusual Canal Morphology in Mandibular Premolars With Two Distal and One Mesial Canal: A Case Series.
Jinesh A, Sanjana Jayakumar Nair, Saurabh Gupta, Harsh Chansoria, Gaurav Rawat

Cureus· November 2024

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Mechanical Injury of Thoracic Aorta by Elephant Trunk Graft Limb following Frozen Elephant Trunk Procedure.
Jayakumar Thanathu Krishnan Nair, Dinesh Kumar Sathanantham, Nidheesh Chooraiyil, Vinitha V Nair, Jeevan J Jose

Aorta (Stamford)· August 2024

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AKT1 interacts with DHX9 to Mitigate R Loop-Induced Replication Stress in Ovarian Cancer.
Tzu-Ting Huang, Chih-Yuan Chiang, Jayakumar R Nair, Kelli M Wilson, Ken Cheng

Cancer Res· March 2024

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The CHK1 inhibitor prexasertib in BRCA wild-type platinum-resistant recurrent high-grade serous ovarian carcinoma: a phase 2 trial.
Elena Giudice, Tzu-Ting Huang, Jayakumar R Nair, Grant Zurcher, Ann McCoy

Nat Commun· March 2024

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Editorial: The immunosuppressive tumor microenvironment and strategies to revert its immune regulatory milieu for cancer immunotherapy.
Mazdak Ganjalikhani Hakemi, Gülderen Yanikkaya Demirel, Yangqiu Li, Nair Jayakumar

Front Immunol· July 2023

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overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor-resistant -mutant ovarian cancer.
Nitasha Gupta, Tzu-Ting Huang, Jayakumar R Nair, Daniel An, Grant Zurcher

Sci Transl Med· June 2023

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Distinct roles of treatment schemes and BRCA2 on the restoration of homologous recombination DNA repair and PARP inhibitor resistance in ovarian cancer.
Tzu-Ting Huang, Sandra Sczerba Burkett, Mayank Tandon, Tomomi M Yamamoto, Nitasha Gupta, Jayakumar R Nair

Oncogene· November 2022

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A Phase II Single Arm Pilot Study of the CHK1 Inhibitor Prexasertib (LY2606368) in BRCA Wild-Type, Advanced Triple-Negative Breast Cancer.
Margaret E Gatti-Mays, Fatima H Karzai, Sanaz N Soltani, Alexandra Zimmer, Jeffrey E Green, Jayakumar Nair

Oncologist· December 2020

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Targeting the PI3K/mTOR Pathway Augments CHK1 Inhibitor-Induced Replication Stress and Antitumor Activity in High-Grade Serous Ovarian Cancer.
Tzu-Ting Huang, Ethan Brill, Jayakumar R Nair, Xiaohu Zhang, Kelli M Wilson

Cancer Res· December 2020

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Combination of PARP Inhibitor Olaparib, and PD-L1 Inhibitor Durvalumab, in Recurrent Ovarian Cancer: a Proof-of-Concept Phase II Study.
Erika J Lampert, Alexandra Zimmer, Michelle Padget, Ashley Cimino-Mathews, Jayakumar R Nair

Clin Cancer Res· August 2020

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Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer.
Jayakumar Nair, Tzu-Ting Huang, Junko Murai, Brittany Haynes, Patricia S Steeg

Oncogene· August 2020

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Clinical outcomes of prexasertib monotherapy in recurrent wild-type high-grade serous ovarian cancer involve innate and adaptive immune responses.
Erika J Lampert, Ashley Cimino-Mathews, Joo Sang Lee, Jayakumar Nair, Min-Jung Lee

J Immunother Cancer· July 2020

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Chest wall reconstruction: success of a team approach-a 12-year experience from a tertiary care institution.
Lekshmi Malathi, Sankar Das, Jayakumar Thanathu Krishnan Nair, Aniraj Rajappan

Indian J Thorac Cardiovasc Surg· January 2020

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Patients with BRCA mutated ovarian cancer may have fewer circulating MDSC and more peripheral CD8 T cells compared with women with BRCA wild-type disease during the early disease course.
Jung-Min Lee, Dana-Adriana Botesteanu, Yusuke Tomita, Akira Yuno, Min-Jung Lee, Jayakumar R Nair

Oncol Lett· October 2019

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Should all tubercular cavities be left alone? Lessons from a heart transplant.
Vinitha Viswambharan Nair, Kiran Vishnu Narayan, Shobha Kurian Pulikottil, Joseph Thomas Kathayanat, Nidheesh Chooriyil, Jayakumar Thanathu Krishnan Nair

Indian J Thorac Cardiovasc Surg· January 2019

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"Not all bullae are synonymous with COPD"-a rare congenital anomaly described.
Vinitha Viswambharan Nair, Kiran Vishnu Narayan, Jayakumar Thanathu Krishnan Nair

Indian J Thorac Cardiovasc Surg· January 2019

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Lifestyle practices, health problems, and quality of life after coronary artery bypass grafting.
Vinitha Viswambharan Nair, Jayakumar Thanathu Krishnan Nair, Shyam Das, Kunal Krishna Singh, Joseph Thomas Kathayanat

Indian J Thorac Cardiovasc Surg· October 2018

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