Publications by authors named "Jayakumar Sundarraj"

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Molecular Targets of Oxidative Stress: Focus on Nuclear Factor Erythroid 2-Related Factor 2 Function in Leukemia and Other Cancers.
Syed K Hasan, Sundarraj Jayakumar, Eliezer Espina Barroso, Anup Jha, Gianfranco Catalano

Cells· May 2025

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Clobetasol propionate, a Nrf-2 inhibitor, sensitizes human lung cancer cells to radiation-induced killing via mitochondrial ROS-dependent ferroptosis.
Archita Rai, Raghavendra S Patwardhan, Sundarraj Jayakumar, Pradnya Pachpatil, Dhruv Das

Acta Pharmacol Sin· July 2024

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Author Correction: PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity.
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg N Brooke

Nat Commun· June 2024

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PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity.
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg N Brooke

Nat Commun· January 2024

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H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function.
Debosree Pal, Manthan Patel, Fanny Boulet, Jayakumar Sundarraj, Olivia A Grant

Nat Struct Mol Biol· July 2023

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Pharmacological characterization of a structurally new class of antibacterial compound, triphenyl-phosphonium conjugated diarylheptanoid: Antibacterial activity and molecular mechanism.
Shweta Kumari, Sundarraj Jayakumar, Subhash C Bihani, Neena Shetake, Raji Naidu

J Biosci· October 2021

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H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci.
Jayakumar Sundarraj, Gillian C A Taylor, Alex von Kriegsheim, Madapura M Pradeepa

Wellcome Open Res· September 2021

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Chemical and biological basis for development of novel radioprotective drugs for cancer therapy.
Rahul Checker, Raghavendra S Patwardhan, Sundarraj Jayakumar, Dharmendra Kumar Maurya, Mayuri Bandekar

Free Radic Res· May 2021

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Oxidative stress associated metabolic adaptations regulate radioresistance in human lung cancer cells.
Babita Singh, Raghavendra S Patwardhan, Sundarraj Jayakumar, Deepak Sharma, Santosh K Sandur

J Photochem Photobiol B· December 2020

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Antibacterial activity of new structural class of semisynthetic molecule, triphenyl-phosphonium conjugated diarylheptanoid.
Shweta Kumari, Sundarraj Jayakumar, Gagan D Gupta, Subhash C Bihani, Deepak Sharma

Free Radic Biol Med· November 2019

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Mitochondrial targeted curcumin exhibits anticancer effects through disruption of mitochondrial redox and modulation of TrxR2 activity.
Sundarraj Jayakumar, Raghavendra S Patwardhan, Debojyoti Pal, Babita Singh, Deepak Sharma

Free Radic Biol Med· December 2017

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Dimethoxycurcumin, a metabolically stable analogue of curcumin enhances the radiosensitivity of cancer cells: Possible involvement of ROS and thioredoxin reductase.
Sundarraj Jayakumar, R S Patwardhan, Debojyoti Pal, Deepak Sharma, Santosh K Sandur

Biochem Biophys Res Commun· September 2016

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Cellular and molecular effects of beta radiation from I-131 on human tumor cells: a comparison with gamma radiation.
Chandan Kumar, Sundarraj Jayakumar, Badri N Pandey, Grace Samuel, Meera Venkatesh

Curr Radiopharm· October 2015

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Nrf2 facilitates repair of radiation induced DNA damage through homologous recombination repair pathway in a ROS independent manner in cancer cells.
Sundarraj Jayakumar, Debojyoti Pal, Santosh K Sandur

Mutat Res· September 2015

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Differential response of DU145 and PC3 prostate cancer cells to ionizing radiation: role of reactive oxygen species, GSH and Nrf2 in radiosensitivity.
Sundarraj Jayakumar, Amit Kunwar, Santosh K Sandur, Badri N Pandey, Ramesh C Chaubey

Biochim Biophys Acta· January 2014

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The potential value of the neutral comet assay and the expression of genes associated with DNA damage in assessing the radiosensitivity of tumor cells.
Sundarraj Jayakumar, Hari N Bhilwade, Badri N Pandey, Santosh K Sandur, Ramesh C Chaubey

Mutat Res· October 2012

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