Publications by authors named "Jayakumar Surendradoss"

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Effects of Atrasentan on Kidney Gene Transcription, Mesangial Cell Proliferation, and Proteinuria in Immunoglobulin A Nephropathy.
Jay J Kuo, Joyce Wu, Marvin G Gunawan, Mark T McConnell, Jeff Lester, Jayakumar Surendradoss

Kidney360· December 2025

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Characterization of CHK-336, A First-in-Class, Liver-Targeted, Small-Molecule Lactate Dehydrogenase Inhibitor for Hyperoxaluria Treatment.
Jennifer H Cox, Marc-Olivier Boily, Alexandre Caron, Tao Sheng, Joyce Wu, Jayakumar Surendradoss

J Am Soc Nephrol· April 2025

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Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria.
Jinyue Ding, Rajesh Gumpena, Marc-Olivier Boily, Alexandre Caron, Oliver Chong, Jayakumar Surendradoss

ACS Med Chem Lett· July 2021

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Development of Novel Monoamine Oxidase-B (MAO-B) Inhibitors with Reduced Blood-Brain Barrier Permeability for the Potential Management of Noncentral Nervous System (CNS) Diseases.
Ronan Gealageas, Alice Devineau, Pauline P L So, Catrina M J Kim, Jayakumar Surendradoss

J Med Chem· August 2018

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Evaluation of in situ generated valproyl 1-O-β-acyl glucuronide in valproic acid toxicity in sandwich-cultured rat hepatocytes.
Jayakumar Surendradoss, Thomas K H Chang, Frank S Abbott

Drug Metab Dispos· November 2014

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A rapid and sensitive assay to quantify valproyl 1-O-acyl glucuronide in supernatants of sandwich-cultured rat hepatocytes using ultra-high performance liquid chromatography-tandem mass spectrometry.
Jayakumar Surendradoss, András Szeitz, Xiao Wei Teng, Thomas K H Chang, Frank S Abbott

J Chromatogr B Analyt Technol Biomed Life Sci· August 2013

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Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes.
Jayakumar Surendradoss, Thomas K H Chang, Frank S Abbott

Toxicol Appl Pharmacol· November 2012

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Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity.
Tony K L Kiang, Xiao Wei Teng, Jayakumar Surendradoss, Stoyan Karagiozov, Frank S Abbott

Toxicol Appl Pharmacol· May 2011

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Role of oxidative metabolism in the effect of valproic acid on markers of cell viability, necrosis, and oxidative stress in sandwich-cultured rat hepatocytes.
Tony K L Kiang, Xiao Wei Teng, Stoyan Karagiozov, Jayakumar Surendradoss, Thomas K H Chang

Toxicol Sci· December 2010

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