Publications by authors named "Jean Bennett"

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Recovery of cone-mediated vision in Lebercilin associated retinal ciliopathy after gene therapy: One-year results of a phase I/II trial.
Tomas S Aleman, Katherine E Uyhazi, Alejandro J Roman, Mariejel L Weber, Erin C O'Neil, Jean Bennett

Mol Ther· October 2025

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Retinal Disorders.
José-Alain Sahel, Eyal Banin, Jean Bennett, Jacque L Duncan, Botond Roska

Cold Spring Harb Perspect Med· December 2024

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Retinal Degeneration Associated With Biallelic RDH12 Variants: Longitudinal Evaluation of Retinal Structure and Visual Function in Pediatric Patients.
Tomas S Aleman, Alejandro J Roman, Katherine E Uyhazi, Yu You Jiang, Emma C Bedoukian, Jean Bennett

Invest Ophthalmol Vis Sci· December 2024

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Central visual pathways affected by degenerative retinal disease before and after gene therapy.
Manzar Ashtari, Jean Bennett, David A Leopold

Brain· September 2024

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Report From the Second Global Scientific Conference on Clinical Trial Design and Outcome Measures for RDH12-Associated Inherited Retinal Degeneration.
Silvia Cerolini, Jean Bennett, Bart P Leroy, Todd Durham, Courtney Coates

Transl Vis Sci Technol· August 2024

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AAV2 vector optimization for retinal ganglion cell-targeted delivery of therapeutic genes.
Brahim Chaqour, Thu T Duong, Jipeng Yue, Tehui Liu, David Camacho, Jean Bennett

Gene Ther· March 2024

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Overview of Retinal Gene Therapy: Current Status and Future Challenges.
Jean Bennett

Cold Spring Harb Perspect Med· July 2023

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Motion-selective areas V5/MT and MST appear resistant to deterioration in choroideremia.
Edward H Silson, Chris I Baker, Tomas S Aleman, Albert M Maguire, Jean Bennett

Neuroimage Clin· June 2023

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CRISPR-Cas9 correction of a nonsense mutation in rescues lebercilin expression and localization in human retinal organoids.
Tess A V Afanasyeva, Dimitra Athanasiou, Pedro R L Perdigao, Kae R Whiting, Lonneke Duijkers, Jean Bennett

Mol Ther Methods Clin Dev· June 2023

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Dynamic structural remodeling of the human visual system prompted by bilateral retinal gene therapy.
Manzar Ashtari, Philip Cook, Mikhail Lipin, Yinxi Yu, Gui-Shuang Ying, Jean Bennett

Curr Res Neurobiol· June 2023

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Lessons Learned from the Development of the First FDA-Approved Gene Therapy Drug, Voretigene Neparvovec-rzyl.
Jean Bennett, Albert M Maguire

Cold Spring Harb Perspect Med· May 2023

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Optimization and Validation of a Virtual Reality Orientation and Mobility Test for Inherited Retinal Degenerations.
Jean Bennett, Elena M Aleman, Katherine H Maguire, Jennifer Nadelmann, Mariejel L Weber

Transl Vis Sci Technol· January 2023

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Neuroplasticity of the Lateral Geniculate Nucleus in Response to Retinal Gene Therapy in a Group of Patients with Mutations.
Manzar Ashtari, Mikhail Lipin, Michelle Duong, Gui-Shuang Ying, Yinxi Yu, Jean Bennett

Eye Brain· December 2022

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Adeno-Associated Virus Serotype 2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two-Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial.
Tomas S Aleman, Rachel M Huckfeldt, Leona W Serrano, Denise J Pearson, Grace K Vergilio, Jean Bennett

Ophthalmology· October 2022

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AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency.
Kevin Isgrig, Yasuko Ishibashi, Hyun Jae Lee, Jianliang Zhu, Mhamed Grati, Jean Bennett

Mol Ther Methods Clin Dev· September 2022

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Restoration of Vision and Retinal Responses After Adeno-Associated Virus-Mediated Optogenetic Therapy in Blind Dogs.
Sergei Nikonov, Puya Aravand, Arkady Lyubarsky, Roman Nikonov, Angela J Luo, Jean Bennett

Transl Vis Sci Technol· May 2022

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Short-term Assessment of Subfoveal Injection of Adeno-Associated Virus-Mediated hCHM Gene Augmentation in Choroideremia Using Adaptive Optics Ophthalmoscopy.
Jessica I W Morgan, Yu You Jiang, Grace K Vergilio, Leona W Serrano, Denise J Pearson, Jean Bennett

JAMA Ophthalmol· April 2022

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AAV-mediated gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder.
Catherine Argyriou, Anna Polosa, Ji Yun Song, Samy Omri, Bradford Steele, Jean Bennett

Mol Ther Methods Clin Dev· December 2021

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Improving the Quantification of the Lateral Geniculate Nucleus in Magnetic Resonance Imaging Using a Novel 3D-Edge Enhancement Technique.
Mikhail Lipin, Jean Bennett, Gui-Shuang Ying, Yinxi Yu, Manzar Ashtari

Front Comput Neurosci· December 2021

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Durability of Voretigene Neparvovec for Biallelic RPE65-Mediated Inherited Retinal Disease: Phase 3 Results at 3 and 4 Years.
Albert M Maguire, Stephen Russell, Daniel C Chung, Zi-Fan Yu, Amy Tillman, Jean Bennett

Ophthalmology· October 2021

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Refining surgical techniques for efficient posterior semicircular canal gene delivery in the adult mammalian inner ear with minimal hearing loss.
Jianliang Zhu, Jin Woong Choi, Yasuko Ishibashi, Kevin Isgrig, Mhamed Grati, Jean Bennett

Sci Rep· September 2021

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Bardet-Biedl syndrome-7 () shows treatment potential and a cone-rod dystrophy phenotype that recapitulates the non-human primate model.
Tomas S Aleman, Erin C O'Neil, Keli O'Connor, Yu You Jiang, Isabella A Aleman, Jean Bennett

Ophthalmic Genet· June 2021

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Rescue of retinal ganglion cells in optic nerve injury using cell-selective AAV mediated delivery of SIRT1.
Ahmara G Ross, Devin S McDougald, Reas S Khan, Thu T Duong, Kimberly E Dine, Jean Bennett

Gene Ther· May 2021

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A Virtual Reality Orientation and Mobility Test for Inherited Retinal Degenerations: Testing a Proof-of-Concept After Gene Therapy.
Tomas S Aleman, Alexander J Miller, Katherine H Maguire, Elena M Aleman, Leona W Serrano, Jean Bennett

Clin Ophthalmol· March 2021

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Clinical Perspective: Treating RPE65-Associated Retinal Dystrophy.
Albert M Maguire, Jean Bennett, Elena M Aleman, Bart P Leroy, Tomas S Aleman

Mol Ther· February 2021

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