Publications by authors named "Jean C Alvarez"

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Understanding cannabis use and car crashes: Insights from a randomized trial using a driving simulator on THC blood levels and subjective measures of sleepiness and performance.
Bibiana Cardozo, Sarah Hartley, Nicolas Simon, Jean Claude Alvarez

J Safety Res· December 2025

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Severe loperamide misuse in a patient with anxiety - a complication of p-glycoprotein interaction with paroxetine.
Katharina von Fabeck, Jean Claude Alvarez, Emuri Abe, Nicolas Simon

Eur J Clin Pharmacol· December 2025

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A Glimpse Into the Biological Life of Pablo Picasso: Toxicological Study of an Artist's Thumbnail.
Philippe Charlier, Diana Widmaier-Ruiz-Picasso, Jean Claude Alvarez

Drug Test Anal· August 2025

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Can inhaled cannabis users accurately evaluate impaired driving ability? A randomized controlled trial.
Sarah Hartley, Nicolas Simon, Bibiana Cardozo, Islam Amine Larabi, Jean Claude Alvarez

Front Public Health· December 2023

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Characterization of extensive 2-fluorodeschloroketamine metabolism in pooled human liver microsomes, urine and hair from an addicted patient using high-resolution accurate mass spectrometry.
Delphine Joseph, Camille Lesueur, Fanny Zerizer, Alexia Fenot, Jean Claude Alvarez

J Anal Toxicol· July 2023

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The association between TMAO, CMPF, and clinical outcomes in advanced chronic kidney disease: results from the European QUALity (EQUAL) Study.
Lu Dai, Ziad A Massy, Peter Stenvinkel, Nicholas C Chesnaye, Islam Amine Larabi, Jean Claude Alvarez

Am J Clin Nutr· December 2022

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The relationship between uremic toxins and symptoms in older men and women with advanced chronic kidney disease.
Ziad A Massy, Nicholas C Chesnaye, Islam Amine Larabi, Friedo W Dekker, Marie Evans, Jean Claude Alvarez

Clin Kidney J· April 2022

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A 4-days-on and 3-days-off maintenance treatment strategy for adults with HIV-1 (ANRS 170 QUATUOR): a randomised, open-label, multicentre, parallel, non-inferiority trial.
Roland Landman, Pierre de Truchis, Lambert Assoumou, Sidonie Lambert, Jonathan Bellet, Jean C Alvarez, Jean-Claude Alvarez

Lancet HIV· February 2022

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Population Pharmacokinetics of Hydroxychloroquine and 3 Metabolites in COVID-19 Patients and Pharmacokinetic/Pharmacodynamic Application.
Jean Claude Alvarez, Benjamin Davido, Pierre Moine, Isabelle Etting, Djillali Annane

Pharmaceuticals (Basel)· February 2022

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Population pharmacokinetic model of blood THC and its metabolites in chronic and occasional cannabis users and relationship with on-site oral fluid testing.
Jean Claude Alvarez, Sarah Hartley, Isabelle Etting, Mégane Ribot, Nawal Derridj-Ait-Younes

Br J Clin Pharmacol· August 2021

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Metabolic profiling of deschloro-N-ethyl-ketamine and identification of new target metabolites in urine and hair using human liver microsomes and high-resolution accurate mass spectrometry.
Islam Amine Larabi, Fanny Zerizer, Alice Ameline, Isabelle Etting, Delphine Joseph, Jean Claude Alvarez

Drug Test Anal· June 2021

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Reply to the letter to the Editor "Prediction of lopinavir/ritonavir effectiveness in COVID-19 patients: a recall of basic pharmacology concepts".
Nicolas Simon, Jean Claude Alvarez

Eur J Clin Pharmacol· May 2021

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Population pharmacokinetics of lopinavir/ritonavir in Covid-19 patients.
Jean Claude Alvarez, Pierre Moine, Benjamin Davido, Isabelle Etting, Djillali Annane

Eur J Clin Pharmacol· March 2021

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Development and validation of liquid chromatography-tandem mass spectrometry targeted screening of 16 fentanyl analogs and U-47700 in hair: Application to 137 authentic samples.
Islam Amine Larabi, Marie Martin, Isabelle Etting, Gregory Pfau, Yves Edel, Jean Claude Alvarez

Drug Test Anal· September 2020

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Does the Administration of Sevelamer or Nicotinamide Modify Uremic Toxins or Endotoxemia in Chronic Hemodialysis Patients?
Aurelie Lenglet, Nicolas Fabresse, Méline Taupin, Cathy Gomila, Sophie Liabeuf, Jean Claude Alvarez

Drugs· June 2019

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Effect of Smoked Cannabis on Vigilance and Accident Risk Using Simulated Driving in Occasional and Chronic Users and the Pharmacokinetic-Pharmacodynamic Relationship.
Sarah Hartley, Nicolas Simon, Amine Larabi, Isabelle Vaugier, Frédéric Barbot, Jean Claude Alvarez

Clin Chem· May 2019

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Drug-facilitated sexual assault (DFSA) involving 4-methylethcathinone (4-MEC), 3,4-Methylenedioxypyrovalerone (MDPV), and doxylamine highlighted by hair analysis.
Islam Amine Larabi, Marie Martin, Isabelle Etting, Pauline Penot, Nicolas Fabresse, Jean Claude Alvarez

Drug Test Anal· March 2018

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Hair analysis does not allow to discriminate between acute and chronic administrations of a drug in young children.
Jean Claude Alvarez, Laetitia Lasne, Isabelle Etting, Gérard Chéron, Véronique Abadie

Int J Legal Med· January 2018

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Preoperative Evaluation of the Renal Function before the Treatment of Abdominal Aortic Aneurysms.
Raphael Coscas, Sandra Wagner, Eve Vilaine, Albane Sartorius, Isabelle Javerliat, Jean Claude Alvarez

Ann Vasc Surg· April 2017

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Identification and quantification of 4-methylethcathinone (4-MEC) and 3,4-methylenedioxypyrovalerone (MDPV) in hair by LC-MS/MS after chronic administration.
Jean Claude Alvarez, Isabelle Etting, Emuri Abe, Antoine Villa, Nicolas Fabresse

Forensic Sci Int· January 2017

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Quantification of remifentanil and propofol in human plasma: a LC-MS/MS assay validated according to the EMA guideline.
Jean Claude Alvarez, Emuri Abe, Isabelle Etting, Morgan Le Guen, Philippe Devillier

Bioanalysis· April 2016

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A practical tranexamic acid dosing scheme based on population pharmacokinetics in children undergoing cardiac surgery.
Stanislas Grassin-Delyle, Roland Couturier, Emuri Abe, Jean Claude Alvarez, Philippe Devillier

Anesthesiology· April 2013

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An automated method for measurement of methoxetamine in human plasma by use of turbulent flow on-line extraction coupled with liquid chromatography and mass spectrometric detection.
Emuri Abe, Florian Ricard, François Darrouzain, Jean Claude Alvarez

Anal Bioanal Chem· January 2013

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Measurement of atropine and scopolamine in hair by LC-MS/MS after Datura stramonium chronic exposure.
Florian Ricard, Emuri Abe, Charlotte Duverneuil-Mayer, Philippe Charlier, Geoffroy de la Grandmaison, Jean Claude Alvarez

Forensic Sci Int· November 2012

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A validated assay for the quantitative analysis of tranexamic acid in human serum by liquid chromatography coupled with electrospray ionization mass spectrometry.
Stanislas Grassin Delyle, Emuri Abe, Anne Batisse, Benjamin Tremey, Marc Fischler, Jean Claude Alvarez

Clin Chim Acta· March 2010

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