Publications by authors named "Jean D Boyer"

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Siglecs in immunotherapy: current clinical landscape and prospects.
Abhinav Purohit, Ishaan Joshi, Pratik S Bhojnagarwala, Jean D Boyer, J Joseph Kim

Trends Pharmacol Sci· December 2025

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Intramuscular DNA vaccine provides protection in non-human primate and mouse models of SARS-CoV-2.
Subeena Sood, Ebony N Gary, Majed Matar, Jessica Kim, Casey E Hojecki, Jean D Boyer

Front Immunol· June 2025

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Strong immunogenicity & protection in mice with PlaCCine: A COVID-19 DNA vaccine formulated with a functional polymer.
Subeena Sood, Majed M Matar, Jessica Kim, Meredyth Kinsella, Kempaiah Rayavara, Jean D Boyer

Vaccine· February 2024

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DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Elizabeth M Parzych, Jianqiu Du, Ali R Ali, Katherine Schultheis, Drew Frase, Jean D Boyer

Nat Commun· October 2022

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SARS-CoV-2 DNA Vaccine INO-4800 Induces Durable Immune Responses Capable of Being Boosted in a Phase 1 Open-Label Trial.
Kimberly A Kraynyak, Elliott Blackwood, Joseph Agnes, Pablo Tebas, Mary Giffear, Jean D Boyer

J Infect Dis· June 2022

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INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants.
Viviane M Andrade, Aaron Christensen-Quick, Joseph Agnes, Jared Tur, Charles Reed, Jean D Boyer

NPJ Vaccines· October 2021

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Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors.
Robert H Vonderheide, Kimberly A Kraynyak, Anthony F Shields, Autumn J McRee, Jennifer M Johnson, Jean D Boyer

J Immunother Cancer· July 2021

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Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.
Pablo Tebas, ShuPing Yang, Jean D Boyer, Emma L Reuschel, Ami Patel

EClinicalMedicine· January 2021

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Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults.
Srilatha Edupuganti, Stephen C De Rosa, Marnie Elizaga, Yiwen Lu, Xue Han, Jean D Boyer

Vaccines (Basel)· December 2020

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Robust antibody and cellular responses induced by DNA-only vaccination for HIV.
Stephen C De Rosa, Srilatha Edupuganti, Yunda Huang, Xue Han, Marnie Elizaga, Jean D Boyer

JCI Insight· July 2020

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CD8 T Cells Impact Rising PSA in Biochemically Relapsed Cancer Patients Using Immunotherapy Targeting Tumor-Associated Antigens.
Neal D Shore, Matthew P Morrow, Trevor McMullan, Kimberly A Kraynyak, Albert Sylvester, Jean D Boyer

Mol Ther· May 2020

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Clinical and Immunologic Biomarkers for Histologic Regression of High-Grade Cervical Dysplasia and Clearance of HPV16 and HPV18 after Immunotherapy.
Matthew P Morrow, Kimberly A Kraynyak, Albert J Sylvester, Michael Dallas, Dawson Knoblock, Jean D Boyer

Clin Cancer Res· January 2018

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Soluble Factors Secreted by Endothelial Cells Allow for Productive and Latent HIV-1 Infection in Resting CD4 T Cells.
John Henry Morris, Tran Nguyen, Abuoma Nwadike, Mackenzie L Geels, Derrick L Kamp, Jean D Boyer

AIDS Res Hum Retroviruses· February 2017

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Seroprotection of HIV-infected subjects after influenza A(H1N1) vaccination is directly associated with baseline frequency of naive T cells.
Lorenzo A Ramirez, Alexander Daniel, Ian Frank, Pablo Tebas, Jean D Boyer

J Infect Dis· August 2014

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Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions.
Leonel Maldonado, Jessica E Teague, Matthew P Morrow, Iveta Jotova, T C Wu, Jean D Boyer

Sci Transl Med· January 2014

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Immunologic consequences of chemotherapy for ovarian cancer: impaired responses to the influenza vaccine.
Christina S Chu, Jean D Boyer, Abbas Jawad, Kenyetta McDonald, Wade T Rogers

Vaccine· November 2013

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Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice.
Devon J Shedlock, Kendra T Talbott, Stephan J Wu, Christine M Wilson, Karuppiah Muthumani, Jean D Boyer

Hum Vaccin Immunother· November 2012

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IL-4 and IFN-γ induced by human immunodeficiency virus vaccine in a schistosome infection model.
Jiangmei Yin, Anlan Dai, Tatiana Arango, Ravi S Kasinathan, Robert M Greenberg, Jean D Boyer

Hum Vaccin Immunother· November 2012

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Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses.
Mark L Bagarazzi, Jian Yan, Matthew P Morrow, Xuefei Shen, R Lamar Parker, Jean D Boyer

Sci Transl Med· October 2012

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Plasmodium inui infection reduces the efficacy of a simian immunodeficiency virus DNA vaccine in a rhesus macaque model through alteration of the vaccine-induced immune response.
Jiangmei Yin, Maryanne T Vahey, Anlan Dai, Mark G Lewis, Tatiana Arango, Jean D Boyer

J Infect Dis· August 2012

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Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.
Josephine H Cox, Maria G Ferrari, Patricia Earl, James R Lane, Linda L Jagodzinski, Jean D Boyer

Vaccine· February 2012

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High antibody and cellular responses induced to HIV-1 clade C envelope following DNA vaccines delivered by electroporation.
Jiangmei Yin, Anlan Dai, Jonathan Lecureux, Tatiana Arango, Michele A Kutzler, Jean D Boyer

Vaccine· September 2011

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Viral reservoir is suppressed but not eliminated by CD8 vaccine specific lymphocytes.
Jiangmei Yin, Anlan Dai, Anding Shen, Jonathan Lecureux, Mark G Lewis, Jean D Boyer

Vaccine· February 2010

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High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model.
Jiangmei Yin, Anlan Dai, Dominick J Laddy, Jian Yan, Tatiana Arango, Jean D Boyer

Virology· October 2009

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CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads.
Yvonne M Mueller, Duc H Do, Jean D Boyer, Muhamuda Kader, Joseph J Mattapallil

J Immunol· October 2009

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