Publications by authors named "Jean H Overmeyer"

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The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma.
Zehui Li, Nneka E Mbah, Jean H Overmeyer, Jeffrey G Sarver, Sage George

BMC Cancer· January 2019

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Receptor-Mediated Attachment and Uptake of Hyaluronan Conjugates by Breast Cancer Cells.
Kush N Shah, Andrew J Ditto, Douglas C Crowder, Jean H Overmeyer, Hossein Tavana

Mol Pharm· November 2017

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Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.
Nneka E Mbah, Jean H Overmeyer, William A Maltese

Cell Biol Toxicol· June 2017

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Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer indolyl-pyridinyl-propenones: Effects on potency and mode of activity.
Christopher J Trabbic, Sage M George, Evan M Alexander, Shengnan Du, Jennifer M Offenbacher, Jean H Overmeyer

Eur J Med Chem· October 2016

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Synthesis and biological evaluation of indolyl-pyridinyl-propenones having either methuosis or microtubule disruption activity.
Christopher J Trabbic, Jean H Overmeyer, Evan M Alexander, Emily J Crissman, Heather M Kvale

J Med Chem· March 2015

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Non-apoptotic cell death associated with perturbations of macropinocytosis.
William A Maltese, Jean H Overmeyer

Front Physiol· March 2015

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Methuosis: nonapoptotic cell death associated with vacuolization of macropinosome and endosome compartments.
William A Maltese, Jean H Overmeyer

Am J Pathol· June 2014

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Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones.
Christopher J Trabbic, Heather M Dietsch, Evan M Alexander, Peter I Nagy, Michael W Robinson, Jean H Overmeyer

ACS Med Chem Lett· January 2014

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Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death.
Michael W Robinson, Jean H Overmeyer, Ashley M Young, Paul W Erhardt, William A Maltese

J Med Chem· March 2012

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A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells.
Jean H Overmeyer, Ashley M Young, Haymanti Bhanot, William A Maltese

Mol Cancer· June 2011

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Death pathways triggered by activated Ras in cancer cells.
Jean H Overmeyer, William A Maltese

Front Biosci (Landmark Ed)· January 2011

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Induction of nonapoptotic cell death by activated Ras requires inverse regulation of Rac1 and Arf6.
Haymanti Bhanot, Ashley M Young, Jean H Overmeyer, William A Maltese

Mol Cancer Res· October 2010

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Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis.
Jean H Overmeyer, Aparna Kaul, Erin E Johnson, William A Maltese

Mol Cancer Res· June 2008

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Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways.
Aparna Kaul, Jean H Overmeyer, William A Maltese

Cell Signal· May 2007

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Tyrosine phosphorylation of Rab proteins.
Jean H Overmeyer, William A Maltese

Methods Enzymol· April 2006

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Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes.
Erin E Johnson, Jean H Overmeyer, William T Gunning, William A Maltese

J Cell Sci· April 2006

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Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking.
Xuehuo Zeng, Jean H Overmeyer, William A Maltese

J Cell Sci· January 2006

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Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells.
Jane Ding, Gwendolyn Soule, Jean H Overmeyer, William A Maltese

Biochem Biophys Res Commun· December 2003

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