Publications by authors named "Jean-Louis Merlin"

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Sensitive cell-free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study.
Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Jean-Louis Merlin

Oncol Lett· January 2026

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Radiotherapy in the management of PDAC, from past to present.
Julie Dardare, Nicolas Martz, Andréa Witz, Margaux Betz, Cassandra Michel, Jean-Louis Merlin

Transl Oncol· January 2026

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A Novel Droplet Digital PCR Assay for BRCA1 and RAD51C Methylation: Advancing Homologous Recombination Deficiency Detection in Ovarian Cancer.
Cassandra Michel, Alizée Simon, Andréa Witz, Idrissia Hanriot, Julie Dardare, Jean Louis Merlin

J Mol Diagn· October 2025

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Improving Radiation Therapy in Pancreatic Cancer Through Radiosensitization Strategies.
Julie Dardare, Nicolas Martz, Andréa Witz, Margaux Betz, Cassandra Michel, Jean-Louis Merlin

Int J Radiat Oncol Biol Phys· September 2025

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Study of the survival of patients with head and neck cancer in relation to Circulating Tumor Cells (CTCs).
Romina Mastronicola, Elise Kayser, Pauline Le Roux, Agathe Barrat, Alexandre Aubertin, Jean-Louis Merlin

PLoS One· May 2025

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Decoding mutational signatures in breast cancer: Insights from a multi-cohort study.
Margaux Betz, Andréa Witz, Julie Dardare, Cassandra Michel, Vincent Massard, Jean-Louis Merlin

Transl Oncol· March 2025

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Homologous recombination deficiency (HRD) testing landscape: clinical applications and technical validation for routine diagnostics.
Andréa Witz, Julie Dardare, Margaux Betz, Cassandra Michel, Marie Husson, Jean-Louis Merlin

Biomark Res· February 2025

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DDB2 expression lights the way for precision radiotherapy response in PDAC cells, with or without olaparib.
Julie Dardare, Andréa Witz, Margaux Betz, Aurélie François, Laureline Lamy, Jean-Louis Merlin

Cell Death Discov· September 2024

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[Development of an artificial intelligence system to improve cancer clinical trial eligibility screening].
Maud Gédor, Emmanuel Desandes, Mélanie Chesnel, Jean-Louis Merlin, Frédéric Marchal

Bull Cancer· May 2024

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Tumor-derived cell-free DNA and circulating tumor cells: partners or rivals in metastasis formation?
Andréa Witz, Julie Dardare, Margaux Betz, Pauline Gilson, Jean-Louis Merlin

Clin Exp Med· January 2024

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Integrated Molecular Characterization of HER2-Low Breast Cancer Using Next Generation Sequencing (NGS).
Jean-Louis Merlin, Marie Husson, Nassim Sahki, Pauline Gilson, Vincent Massard

Biomedicines· November 2023

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CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines.
Andréa Witz, Julie Dardare, Aurélie Francois, Marie Husson, Marie Rouyer, Jean-Louis Merlin

Sci Rep· October 2023

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Gene Mutations and Liquid Biopsy in ER-Positive Breast Cancers: A Small Step Forward, a Giant Leap for Personalization of Endocrine Therapy?
Margaux Betz, Vincent Massard, Pauline Gilson, Andréa Witz, Julie Dardare, Jean-Louis Merlin

Cancers (Basel)· October 2023

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Validation of the Idylla GeneFusion assay to detect fusions and MET exon-skipping in non-small cell lung cancers.
Pauline Gilson, Celso Pouget, Richard Belmonte, Smahane Fadil, Jessica Demange, Jean-Louis Merlin

Sci Rep· August 2023

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Personalized follow-up of circulating DNA in resected stage III/IV melanoma: PERCIMEL multicentric prospective study protocol.
Lionnel Geoffrois, Alexandre Harlé, Nassim Sahki, Aleksandra Sikanja, Florence Granel-Brocard, Jean-Louis Merlin

BMC Cancer· June 2023

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[Clinical epidemiology and biostatistic innovations 2023 - Welcome In Nancy].
Francis Guillemin, Jean-Louis Merlin

Rev Epidemiol Sante Publique· May 2023

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DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy.
Julie Dardare, Andréa Witz, Margaux Betz, Aurélie Francois, Morgane Meras, Jean-Louis Merlin

Front Oncol· December 2022

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Conversational hypnosis versus standard of care to reduce anxiety in patients undergoing marker placement under radiographic control prior to breast cancer surgery: A randomized, multicenter trial.
Lydie Lemoine, Virginie Adam, Xavier Galus, Pascale Siles, Agnès Coulon, Jean-Louis Merlin

Front Psychol· November 2022

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Intraoperative prediction of non-sentinel lymph node metastases in breast cancer using cytokeratin 19 mRNA copy number: A retrospective analysis.
Heloïse Pina, Julia Salleron, Pauline Gilson, Marie Husson, Marie Rouyer, Jean-Louis Merlin

Mol Clin Oncol· March 2022

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Deciphering Tumour Heterogeneity: From Tissue to Liquid Biopsy.
Pauline Gilson, Jean-Louis Merlin, Alexandre Harlé

Cancers (Basel)· March 2022

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A phase II randomised study of preoperative trastuzumab alone or combined with everolimus in patients with early HER2-positive breast cancer and predictive biomarkers (RADHER trial).
Mario Campone, Thomas Bachelot, Isabelle Treilleux, Barbara Pistilli, Julia Salleron, Jean-Louis Merlin

Eur J Cancer· November 2021

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A NGS-based Blood Test For the Diagnosis of Invasive HPV-associated Carcinomas with Extensive Viral Genomic Characterization.
Xavier Sastre-Garau, Mamadou Diop, Fernando Martin, Gilles Dolivet, Frédéric Marchal, Jean-Louis Merlin

Clin Cancer Res· October 2021

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Epithelial to Mesenchymal Transition in Patients with Pancreatic Ductal Adenocarcinoma: State-of-the-Art and Therapeutic Opportunities.
Julie Dardare, Andréa Witz, Jean-Louis Merlin, Agathe Bochnakian, Paul Toussaint

Pharmaceuticals (Basel)· July 2021

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Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers.
Pauline Gilson, Chloé Saurel, Julia Salleron, Marie Husson, Jessica Demange, Jean-Louis Merlin

Sci Rep· May 2021

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Detection of Microsatellite Instability: State of the Art and Future Applications in Circulating Tumour DNA (ctDNA).
Pauline Gilson, Jean-Louis Merlin, Alexandre Harlé

Cancers (Basel)· March 2021

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