Publications by authors named "Jean-Robert Labrosse"

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Discovery of (2S)-8-[(3R)-3-methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: a novel potent and selective inhibitor of Vps34 for the treatment of solid tumors.
Benoit Pasquier, Youssef El-Ahmad, Bruno Filoche-Rommé, Christine Dureuil, Florence Fassy, Jean-Robert Labrosse

J Med Chem· January 2015

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Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{[(4-cyanophenyl)(4h-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: synthesis, SAR, crystal structure, and in vitro and in vivo activities.
Paul M Wood, L W Lawrence Woo, Jean-Robert Labrosse, Mark P Thomas, Mary F Mahon

ChemMedChem· September 2010

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Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity.
Paul M Wood, L W Lawrence Woo, Jean-Robert Labrosse, Melanie N Trusselle, Sergio Abbate

J Med Chem· July 2008

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