Publications by authors named "Jedd D Wolchok"

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Thrombospondin-1-CD47 signaling contributes to the development of T cell exhaustion in cancer.
Chien-Huan Weng, Anais Assouvie, Lauren Dong, Jean-Christophe Beltra, Sadna Budhu, Jedd D Wolchok

Nat Immunol· December 2025

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Antimicrobial Exposure and Immune-Related Cutaneous Adverse Events During Immune Checkpoint Blockade Therapy.
Lukas Kraehenbuehl, Stephanie Gu, Jessica A Lavery, Sara Chekalil, Kwami F Ketosugbo, Jedd D Wolchok

JAMA Dermatol· December 2025

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Changing Role of Adjuvant Therapy in Stage III Melanoma.
Paul B Chapman, Jedd D Wolchok

N Engl J Med· October 2025

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Dual Immune Check Point Blockade in -Unmethylated Newly Diagnosed Glioblastoma: NRG Oncology BN007, a Randomized Phase II/III Clinical Trial.
Andrew B Lassman, Mei-Yin C Polley, Fabio M Iwamoto, Andrew E Sloan, Tony J C Wang, Jedd D Wolchok

J Clin Oncol· September 2025

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Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling.
Alexandre Pellan Cheng, Adam J Widman, Anushri Arora, Itai Rusinek, Aaron Sossin, Jedd D Wolchok

Nat Methods· May 2025

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Host Tissue Factors Predict Immune Surveillance and Therapeutic Outcomes in Gastric Cancer.
Miseker Abate, Emily E Stroobant, Teng Fei, Ya-Hui Lin, Shoji Shimada, Jedd D Wolchok

Cancer Immunol Res· April 2025

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RNA neoantigen vaccines prime long-lived CD8 T cells in pancreatic cancer.
Zachary Sethna, Pablo Guasp, Charlotte Reiche, Martina Milighetti, Nicholas Ceglia, Jedd D Wolchok

Nature· March 2025

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Nivolumab plus Ipilimumab in Advanced Melanoma. Reply.
Jedd D Wolchok, F Stephen Hodi, James Larkin

N Engl J Med· March 2025

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Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma.
Jedd D Wolchok, Vanna Chiarion-Sileni, Piotr Rutkowski, C Lance Cowey, Dirk Schadendorf

N Engl J Med· January 2025

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Durable complete response in a patient with leptomeningeal melanoma after treatment with dabrafenib, trametinib, and nivolumab.
Sarah E Lochrin, Darren J Buonocore, Robert J Young, Thomas J Kaley, Michael A Postow, Jedd D Wolchok

Pigment Cell Melanoma Res· November 2024

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Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma.
Michelangelo Marasco, Dinesh Kumar, Tessa Seale, Santiago Garcia Borrego, Esther Kaplun, Jedd D Wolchok

Cell Rep Med· November 2024

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Clinical benefit with tebentafusp in a patient with GNAQ mutant metastatic blue nevus-associated melanoma.
Matthew R Kudelka, Allison L Richards, Philip Friedlander, Jedd D Wolchok, Andrea P Moy

J Immunother Cancer· November 2024

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Intermittent MEK Inhibition with GITR Costimulation Rescues T-cell Function for Increased Efficacy with CTLA-4 Blockade in Solid Tumor Models.
Lauren Dong, Hyejin Choi, Sadna Budhu, Isabell Schulze, Svena Verma, Jedd D Wolchok

Cancer Immunol Res· October 2024

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Pharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor models.
Svena Verma, Sadna Budhu, Inna Serganova, Lauren Dong, Levi M Mangarin, Jedd D Wolchok

J Clin Invest· September 2024

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TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models.
Christopher S Hackett, Daniel Hirschhorn, Meixian S Tang, Terence J Purdon, Yacine Marouf, Jedd D Wolchok

Mol Ther Oncol· September 2024

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Early On-Treatment Assessment of T Cells, Cytokines, and Tumor DNA with Adaptively Dosed Nivolumab + Ipilimumab: Final Results from the Phase 2 ADAPT-IT Study.
James W Smithy, Hannah L Kalvin, Fiona D Ehrich, Ronak Shah, Matthew Adamow, Jedd D Wolchok

Clin Cancer Res· August 2024

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Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment.
Adam J Widman, Minita Shah, Amanda Frydendahl, Daniel Halmos, Cole C Khamnei, Jedd D Wolchok

Nat Med· June 2024

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Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model.
Sadna Budhu, Kwanghee Kim, Wesley Yip, Stephen La Rosa, Sylvia Jebiwott, Jedd D Wolchok

Front Oncol· June 2024

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Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies.
Anton Dobrin, Pieter L Lindenbergh, Yuzhe Shi, Karlo Perica, Hongyao Xie, Jedd D Wolchok

Nat Cancer· May 2024

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Having the cake and eating it? Clofazimine boosts immunotherapy while limiting side effects.
Lukas Kraehenbuehl, Jedd D Wolchok, Taha Merghoub, Daniel Hirschhorn

Cancer Cell· May 2024

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The side effect registry immuno-oncology (SERIO) - A tool for systematic analysis of immunotherapy-induced side effects.
Carolin Ertl, Theresa Ruf, Dirk Mentzer, Mingzi Kong, Rafaela Kramer, Jedd D Wolchok

Eur J Cancer· March 2024

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APR-246 increases tumor antigenicity independent of p53.
Judith Michels, Divya Venkatesh, Cailian Liu, Sadna Budhu, Hong Zhong, Jedd D Wolchok

Life Sci Alliance· January 2024

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Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib.
Paul B Chapman, Mark Klang, Michael A Postow, Alexander Noor Shoushtari, Ryan J Sullivan, Jedd D Wolchok

Cancer Res Commun· December 2023

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Tumor dynamics in patients with solid tumors treated with pembrolizumab beyond disease progression.
Brian G Topp, Madhav Channavazzala, Kapil Mayawala, Dinesh P De Alwis, Eric Rubin, Jedd D Wolchok

Cancer Cell· September 2023

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MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
Yu Qian, Ana Galan-Cobo, Irene Guijarro, Minghao Dang, David Molkentine, Jedd D Wolchok

Cancer Cell· July 2023

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